Spyre Therapeutics Inc Share Price Today (NASDAQ: SYRE)

Name: Spyre Therapeutics Inc Share Price (NASDAQ: SYRE) - Stock Quote, Live Chart
Brand: INDmoney
Rating: 4.7 (371551 reviews)

Spyre Therapeutics Inc share price is 15.2 & ₹1,301.80 as on 17 May 2025, 2.30 'hrs' IST

$15.2

▲

0.66

(4.54%)

Market is closed - opens 7 PM, 19 May 2025

View live Spyre Therapeutics Inc share price in Dollar and Rupees. Guide to invest in Spyre Therapeutics Inc stock from India, including Indian investor sentiment. Get details on Indian mutual funds investing in Spyre Therapeutics Inc, along with analyst recommendations, forecasts, and comprehensive financials.

Spyre Therapeutics Inc share price movements

Today's Low: $14.97
Today's High: $15.31
$15.20
1.51%
Downside
Day's Volatility :2.19%
Upside
0.69%
52 Weeks Low: $10.91
52 Weeks High: $40.26
$15.20
28.22%
Downside
52 Weeks Volatility :72.9%
Upside
62.25%

Spyre Therapeutics Inc (SYRE) Returns

Period	Spyre Therapeutics Inc	Index (Russel 2000)
3 Months	-31.13%	0.0%
6 Months	-46.98%	0.0%
1 Year	-58.77%	0.0%
3 Years	-59.47%	-0.4%

Spyre Therapeutics Inc (SYRE) Key Statistics

in dollars & INR

Previous Close	$14.54
Open	$14.97
Today's High	$15.305
Today's Low	$14.97
Market Capitalization	$916.2M
Today's Volume	$340.7K
52 Week High	$40.26
52 Week Low	$10.91
Revenue TTM	$0.0
EBITDA	$-207.8M
Earnings Per Share (EPS)	$-3.06
Profit Margin	0.0%
Quarterly Earnings Growth YOY	-1.0%
Return On Equity TTM	-65.82%

How to invest in Spyre Therapeutics Inc Stock (SYRE) from India?

It is very easy for Indian residents to invest directly in Spyre Therapeutics Inc from India. Indian investors can open a free US stocks account on the INDmoney app. You can find live prices of the Spyre Therapeutics Inc stock in both Indian Rupees (INR) and US Dollars (USD). Search for Spyre Therapeutics Inc or SYRE on the INDmoney app and click on Buy or SIP. You can invest by choosing quantities of shares of Spyre Therapeutics Inc or rupee/ dollar value or set up a fixed SIP amount to be invested every month or week.

For example: You can easily buy Rs.100 worth of Spyre Therapeutics Inc shares which would translate to 0.056 fractional shares of Spyre Therapeutics Inc as of today. Learn more about fractional investing.

Indians can now also easily transfer and add money to their US stocks account via the INDmoney app. Invest in US Stocks from India , including recognised companies like Spyre Therapeutics Inc, in just a few clicks!

Returns in Spyre Therapeutics Inc (SYRE) for Indian investors in Rupees

The Spyre Therapeutics Inc stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

Investment Value

₹1,00,000

Spyre Therapeutics Inc investment value today

Current value as on today

₹43,957

Returns

₹56,043

(-56.04%)

Returns from Spyre Therapeutics Inc Stock

₹58,774 (-58.77%)

Dollar Returns

₹2,731 (+2.73%)

Indian investors sentiment towards Spyre Therapeutics Inc (SYRE)

-25%

Period: Apr 18, 2025 to May 18, 2025. Change in 30 Days versus previous period

Search interest for Spyre Therapeutics Inc Stock from India on INDmoney has decreased by -25% in the last 30 days, reflecting a downward trend in search activity.

Analyst Recommendation on Spyre Therapeutics Inc

Rating

Trend

Buy

92%Buy

7%Hold

0%Sell

Based on 13 Wall street analysts offering stock ratings for Spyre Therapeutics Inc(by analysts ranked 0 to 5 stars)

Insights on SYRE Stock (Ticker Symbol: SYRE)

Price Movement
In the last 3 months, SYRE stock has moved down by -32.1%
Increasing Revenue
Revenue is up for the last 4 quarters, 168.0K → 1.04M (in $), with an average increase of 40.1% per quarter
Increasing Net Profit
Netprofit is up for the last 3 quarters, -69.02M → -44.77M (in $), with an average increase of 24.2% per quarter
SYRE vs ALNY (1 yr)
In the last 1 year, Alnylam Pharmaceuticals, Inc. has given 90.9% return, outperforming this stock by 150.7%
SYRE vs ALNY (3 yr)
In the last 3 years, Alnylam Pharmaceuticals, Inc. has given 120.4% return, outperforming this stock by 180.1%

Spyre Therapeutics Inc (SYRE) Vs Peers

Returns

Ratio's

Overview

Company Name	1 Month	6 Month	1 Year	3 Years	5 Years
Spyre Therapeutics Inc	12.01%	-46.98%	-58.77%	-59.47%	-92.87%
Regeneron Pharmaceuticals, Inc.	5.81%	-22.03%	-39.82%	-10.14%	2.98%
Beone Medicines Ltd	-0.51%	21.5%	30.82%	66.06%	37.54%
Vertex Pharmaceuticals Incorporated	-8.14%	-6.07%	-1.62%	69.63%	54.11%
Alnylam Pharmaceuticals, Inc.	22.5%	22.76%	89.78%	115.57%	98.77%

Company Name	P/E Ratio	P/B Ratio	PEG Ratio	EPS	ROE	ROA	Div Yield	BVPS
Spyre Therapeutics Inc	1.72	NA	NA	-2.9	-0.66	-0.25	NA	5.42
Regeneron Pharmaceuticals, Inc.	15.11	15.11	1.28	35.5	0.16	0.07	0.01	277.5
Beone Medicines Ltd	NA	NA	NA	1.5	-0.11	-0.03	NA	32.42
Vertex Pharmaceuticals Incorporated	32.84	NA	2.61	18.0	-0.06	0.12	NA	64.2
Alnylam Pharmaceuticals, Inc.	NA	NA	-0.49	1.01	-15.01	-0.02	NA	0.89

Company Name	Analyst View	Market Cap	5 Years Return %	PE Ratio	Profit Margin
Spyre Therapeutics Inc	Buy	$916.2M	-92.87%	1.72	0.0%
Regeneron Pharmaceuticals, Inc.	Buy	$64.2B	2.98%	15.11	31.94%
Beone Medicines Ltd	NA	$26.3B	37.54%	NA	-9.4%
Vertex Pharmaceuticals Incorporated	Buy	$112.6B	54.11%	32.84	-8.91%
Alnylam Pharmaceuticals, Inc.	Buy	$37.2B	98.77%	NA	-11.49%

About Spyre Therapeutics Inc

Spyre Therapeutics, Inc., a clinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD). It develops SPY001, a human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4ß7 integrin being developed for the treatment of IBD (ulcerative colitis and Crohn's disease). The company is developing SPY002, a human monoclonal antibody (mAb)candidates designed to bind to tumor necrosis factor-like ligand 1A; and SPY120, a combination of SPY001 (anti-a4ß7) and SPY002 (anti-TL1A) antibodies, which are in preclinical studies. In addition, its other early-stage programs include SPY003, an anti-IL-23 mAb; SPY004; SPY130, a combination of anti-a4ß7 and anti-IL-23 mAbs; and SPY230, a combination of anti-TL1A and anti-IL-23 mAbs. The company was formerly known as Aeglea BioTherapeutics, Inc. and changed its name to Spyre Therapeutics, Inc. in November 2023. The company was incorporated in 2013 and is based in Waltham, Massachusetts.

Organization	Spyre Therapeutics Inc
Employees	73
CEO	Dr. Cameron Turtle DPHIL, Ph.D.
Industry	Miscellaneous

Management People of Spyre Therapeutics Inc

Name	Title
Dr. Cameron Turtle DPHIL, Ph.D.	CEO & Director
Mr. Scott L. Burrows	Chief Financial Officer
Dr. Sheldon Sloan M.B.E., M.D.	Chief Medical Officer
Dr. Janet Gunzner-Toste M.B.A., Ph.D.	Senior Vice President of Operations
Mr. Brian Connolly	Chief Technical Officer
Mr. Eric McIntyre	Vice President of Finance & Investor Relations
Ms. Heidy Abreu King-Jones J.D., L.L.M.	Chief Legal Officer & Corporate Secretary
Mr. James Myers	Vice President of Quality & Compliance
Dr. Justin LaFountaine Ph.D.	Senior Vice President of Corporate Development
Ms. Melissa Cooper	Senior Vice President of People

Important FAQs about investing in SYRE Stock from India :

Can Indians buy Spyre Therapeutics Inc shares?

Yes, Indians can invest in the Spyre Therapeutics Inc (SYRE) from India.

With INDmoney, you can buy Spyre Therapeutics Inc at 0 brokerage. The step-by-step process is as follows:

Open your zero cost US Stocks account and zero balance IND linked savings a/c (this can be done in less than 3 minutes)
Transfer funds to your US Stocks account using your IND linked savings a/c (It takes 24 hours excluding Saturday and Sunday). With INDmoney, you get the best INR USD exchange rates.
Once funds are transferred successfully, you can buy Spyre Therapeutics Inc at zero transaction cost.

How can I buy Spyre Therapeutics Inc shares from India?

It is very easy to buy Spyre Therapeutics Inc from India. With INDmoney, you can open a US stocks account in less than 3 minutes. Transfer funds in 24 hours and buy stocks very easily - that too at 0 brokerage. All this is done at 0 account opening & management fee, 0 brokerages, and at the same time you get the best rupee-US dollar exchange rate.

Can Fractional shares of Spyre Therapeutics Inc (SYRE) be purchased?

Yes, you can buy fractional shares of Spyre Therapeutics Inc with INDmoney app.

What are the documents required to start investing in Spyre Therapeutics Inc stocks?

To start investing in Spyre Therapeutics Inc, You will need the following documents:

Proof of Identification (PAN, Aadhaar etc)
Proof of address (Aadhaar, Voter ID etc)

These documents are required as per RBI's guidelines to create your IND linked savings a/c so that you can execute for global fund transfer. The entire process is paperless and can be completed seamlessly.

What is Spyre Therapeutics Inc share price today?

Spyre Therapeutics Inc share price today stands at $15.20, Open: $14.97 ; Previous Close: $14.54 ; High: $15.31 ; Low: $14.97 ; 52 Week High: $40.26 ; 52 Week Low: $10.91.

The stock opens at $14.97, after a previous close of $14.54. The stock reached a daily high of $15.31 and a low of $14.97, with a 52-week high of $40.26 and a 52-week low of $10.91.