Spyre Therapeutics Inc. Stock Performance
as on April 15, 2026 at 6:59 am IST
Day's Low
Day's High
$60.75$67.68
4.94%
Downside
5.90%
Upside

52 Week's Low
52 Week's High
$12.04$75.00
81.16%
Downside
17.35%
Upside

Spyre Therapeutics Inc. share price movements today
- Previous Close
- $63.27
- Open
- $66.16
- Volume
- 1.7M
- Day's Low - High
- $60.75 - $67.68
- 52 Week Low - High
- $12.04 - $75.00
Spyre Therapeutics Inc. Historical Returns
- 1 Month Return
- + 58.61 %
- 3 Month Return
- + 90.8 %
- 1 Year Return
- + 385.94 %
- 3 Year Return
- 0 %
- 5 Year Return
- 0 %
Spyre Therapeutics Inc. Stock Fundamentals & Key Indicators
Check Spyre Therapeutics Inc. market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.
Market Cap
$4.0B
EPS (TTM)
-2.8386
Dividend Yield
0.00%
Quarterly Earnings Growth YOY
-1.00%
PE Ratio (TTM)
0PEG Ratio
0EBITDA
-207.8M
Revenue (TTM)
-
Profit Margin
0.00%
Return On Equity TTM
-25.17%
Spyre Therapeutics Inc. vs Peer Comparison
Compare market cap, revenue, PE, and other key metrics of Spyre Therapeutics Inc. with its industry peers.
Company | Analyst View | Market Cap | 5 Years Return % | PE Ratio | Profit Margin % |
|---|---|---|---|---|---|
| BUY | $4.0B | NA | NA | 0.00% | |
| BUY | $42.7B | 140.76% | 138.84 | 8.45% | |
| BUY | $111.0B | 102.67% | 28.5 | 32.94% | |
| NA | $35.6B | NA | 124.86 | 5.37% | |
| BUY | $79.2B | 55.14% | 18.05 | 31.41% |
Stock Returns calculator for Spyre Therapeutics Inc. Stock including INR - Dollar returns
The Spyre Therapeutics Inc. stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.
*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.
Investment Value
₹1,00,000
Spyre Therapeutics Inc. investment value today
Current value as on today
₹5,30,983
Returns
₹4,30,983
(+430.98%)
Returns from Spyre Therapeutics Inc. Stock
₹3,90,860 (+390.86%)
Dollar Impact
₹40,122 (+40.12%)
Analyst Recommendation on Spyre Therapeutics Inc. Stock
Based on 13 analysts
92.31%
Buy
7.69%
Hold
0.00%
Sell
Based on 13 analysts, 92.31% of analysts recommend a 'BUY' rating for Spyre Therapeutics Inc.. Average target price of $64.36
Spyre Therapeutics Inc. Share Price Target
Get share price movements and forecasts by analysts on Spyre Therapeutics Inc..
What analysts predicted
0.7%UPSIDE
Target Price
$64.36
Current Price
$63.91
Analyzed by
13 Analysts
Target
$64.36
Spyre Therapeutics Inc. target price $64.36, a slight upside of 0.7% compared to current price of $63.91. According to 13 analysts rating.
Spyre Therapeutics Inc. Stock’s Investor Sentiment and Interest
Search interest for Spyre Therapeutics Inc. Stock has decreased by -27% in the last 30 days, reflecting a downward trend in search activity.
Time period: to
Spyre Therapeutics Inc. Quarterly Profit & Loss
All numbers in Millions USD
Spyre Therapeutics Inc. Annual Profit & Loss
All numbers in Millions USD
Spyre Therapeutics Inc. Quarterly Cash Flow
All numbers in Millions USD
Spyre Therapeutics Inc. Annual Cash Flow
All numbers in Millions USD
Spyre Therapeutics Inc. News & Key Events

Today's Timeline - 13 October
Tue, 01:31 AM
-Spyre Therapeutics announces proposed public offering of common stock and pre-funded warrants.
Tue, 06:38 AM
-Spyre Therapeutics prices public offering at $18.50 per share, aiming to raise $275 million.
Insights on Spyre Therapeutics Inc.
Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.
POSITIVE IMPACTRevenue Rich

Revenue is up for the last 5 quarters, 168.0K → 90.49M (in $), with an average increase of 54.8% per quarter
POSITIVE IMPACTPrice Rise

In the last 3 years, SYRE stock has moved up by 1587.2%
POSITIVE IMPACTBest in 1 Year

In the last 1 year, SYRE has outperformed top 5 stocks with highest market-cap in its industry
POSITIVE IMPACTBest in 3 Years

In the last 3 years, SYRE has outperformed top 5 stocks with highest market-cap in its industry
NEGATIVE IMPACTProfit Down

Netprofit is down for the last 2 quarters, -11.18M → -62.53M (in $), with an average decrease of 459.2% per quarter
About Spyre Therapeutics Inc.
| Organisation | Spyre Therapeutics Inc. |
| Headquarters | Building 23, Waltham, MA, United States, 02453 |
| Industry | Biotechnology |
| CEO | Dr. Cameron Turtle DPHIL, Ph.D. |
| E-voting on shares | Click here to vote |
Key Management of Spyre Therapeutics Inc.
Name | Title |
|---|---|
Ms. Melissa Cooper | Senior Vice President of People |
Dr. Cameron Turtle DPHIL, Ph.D. | CEO & Director |
Mr. Scott L. Burrows | Chief Financial Officer |
Dr. Sheldon Sloan M.B.E., M.D. | Chief Medical Officer |
Dr. Justin LaFountaine Ph.D. | Senior Vice President of Corporate Development |
Mr. James Myers | Vice President of Quality & Compliance |
Dr. Janet Gunzner-Toste M.B.A., Ph.D. | Senior Vice President of Operations |
Mr. Brian Connolly | Chief Technical Officer |
Mr. Eric McIntyre | Vice President of Finance & Investor Relations |
Ms. Heidy Abreu King-Jones J.D., L.L.M. | Chief Legal Officer & Corporate Secretary |
FAQs
What is Spyre Therapeutics Inc. share price today?
Spyre Therapeutics Inc. share price today is $63.91 as on at the close of the market. Spyre Therapeutics Inc. share today touched a day high of $67.68 and a low of $60.75.
What is the 52 week high and 52 week low for Spyre Therapeutics Inc. share?
Spyre Therapeutics Inc. share touched a 52 week high of $75 on and a 52 week low of $12.04 on . Spyre Therapeutics Inc. stock price today i.e. is closed at $63.91,which is 14.79% down from its 52 week high and 430.81% up from its 52 week low.
What is Spyre Therapeutics Inc.'s market capitalisation today?
Spyre Therapeutics Inc. market capitalisation is $0.00T as on .
How to invest in Spyre Therapeutics Inc. Stock (SYRE) from India?
- Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
- Step 2: Search for Spyre Therapeutics Inc. on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Spyre Therapeutics Inc. Shares that will get you 0.0235 shares as per Spyre Therapeutics Inc. share price of $63.91 per share as on April 15, 2026 at 1:29 am IST.
What is the minimum amount required to buy Spyre Therapeutics Inc. Stock (SYRE) from India?
Indian investors can start investing in Spyre Therapeutics Inc. (SYRE) shares with as little as ₹93.082 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹930.82 in Spyre Therapeutics Inc. stock (as per the Rupee-Dollar exchange rate as on ).
Based on Spyre Therapeutics Inc. share’s latest price of $63.91 as on April 15, 2026 at 1:29 am IST, you will get 0.1565 shares of Spyre Therapeutics Inc.. Learn more about
fractional shares .