Vertex Pharmaceuticals Incorporated share price logo

Vertex Pharmaceuticals Incorporated Share Price

NASDAQ: VRTX

Large Cap

$409.40

-6.85

(-1.65%)

as on

Vertex Pharmaceuticals Incorporated Stock Performance

as on November 8, 2025 at 2:29 am IST

  • Day's Low

    Day's High

    $406.67
    $416.27
    downward going graph

    0.67%

    Downside

    1.68%

    Upside

    downward going graph
  • 52 Week's Low

    52 Week's High

    $362.5
    $519.88
    downward going graph

    11.46%

    Downside

    26.99%

    Upside

    downward going graph

Vertex Pharmaceuticals Incorporated share price movements today

Previous Close
$416.25
Open
$415.61
Volume
826.7K
Day's Low - High
$406.67 - $416.27
52 Week Low - High
$362.5 - $519.88

Vertex Pharmaceuticals Incorporated Historical Returns

1 Month Return
-2.77 %
3 Month Return
+ 11.71 %
1 Year Return
-20.76 %
3 Year Return
+ 33.6 %
5 Year Return
+ 85.89 %

Vertex Pharmaceuticals Incorporated Stock Fundamentals & Key Indicators

Check Vertex Pharmaceuticals Incorporated market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$105.6B

EPS (TTM)

18.3616

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.05%

PE Ratio (TTM)

29.33

Industry PE ratio

19.200384615384614

PEG Ratio

0.5801

EBITDA

4.7B

Revenue (TTM)

11.7B

Profit Margin

31.35%

Return On Equity TTM

22.31%

Vertex Pharmaceuticals Incorporated Stock Valuation

Track how Vertex Pharmaceuticals Incorporated P/E has moved over time to understand its valuation trends.

Vertex Pharmaceuticals Incorporated in the last 5 years

  • Overview

  • Trends

Lowest (14.94x)

December 31, 2021

Industry (19.20x)

November 8, 2025

Today (29.33x)

November 8, 2025

Highest (34.74x)

September 30, 2025

LowHigh

Today’s Price to Earnings Ratio: 29.33x

Vertex Pharmaceuticals Incorporated vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Vertex Pharmaceuticals Incorporated with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %
BUY$105.6B85.89%29.3331.35%
BUY$40.5B482.44%-16.34-264.83%
BUY$58.2B238.64%1420.941.36%
BUY$68.0B13.75%15.5132.13%

Stock Returns calculator for Vertex Pharmaceuticals Incorporated Stock including INR - Dollar returns

The Vertex Pharmaceuticals Incorporated stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.

Investment Value

₹1,00,000

  • 1Y

  • 3Y

  • 5Y

  • 7Y

  • 10Y

Vertex Pharmaceuticals Incorporated investment value today

Current value as on today

₹84,375

Returns

₹15,625

(-15.63%)

Returns from Vertex Pharmaceuticals Incorporated Stock

₹20,773 (-20.77%)

Dollar Returns*

₹5,147 (+5.15%)

Analyst Recommendation on Vertex Pharmaceuticals Incorporated Stock

Based on 38 analysts

BUY

68.42%

Buy

26.32%

Hold

5.26%

Sell

Based on 38 analysts, 68.42% of analysts recommend a 'BUY' rating for Vertex Pharmaceuticals Incorporated. Average target price of $480.2

Vertex Pharmaceuticals Incorporated Share Price Target

Get share price movements and forecasts by analysts on Vertex Pharmaceuticals Incorporated.

What analysts predicted

14.74%UPSIDE

Target Price

$480.2

Current Price

$409.4

Analyzed by

38 Analysts

Target

$480.20

Vertex Pharmaceuticals Incorporated target price $480.2, a slight upside of 14.74% compared to current price of $409.4. According to 38 analysts rating.

Vertex Pharmaceuticals Incorporated Stock’s Investor Sentiment and Interest

Investment in Vertex Pharmaceuticals Incorporated Shares on INDmoney has dropped by -25.00% over the past 30 days, indicating reduced transactional activity.

Time period: to

Change:-25.00% versus previous 30 day period

Search interest for Vertex Pharmaceuticals Incorporated Stock has decreased by -8% in the last 30 days, reflecting a downward trend in search activity.

Time period: to

Change:-8% versus previous 30 day period

Vertex Pharmaceuticals Incorporated Quarterly Profit & Loss

All numbers in Millions USD

Jun 2023
Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Total Revenue
2,493
2,483
2,517
2,687
2,645
2,771
2,912
2,770
2,964
3,076
Gross Profit
2,184
2,164
2,149
2,344
2,273
2,379
2,488
2,407
2,557
2,661
Operating Income
1,026
1,038
988
1,139
-3,514
1,116
1,026
630
1,151
1,186
EBITDA
1,214
1,232
1,217
1,343
-3,327
1,284
1,184
781
1,338
1,302
Interest Expense
11
10
10
10
9
7
2
3
3
3
Depreciation
41
42
59
53
54
53
46
48
51
-
Income Before Tax
1,161
1,179
1,147
1,279
-3,391
1,224
1,136
730
1,283
1,298
Income Tax Expense
245
143
178
179
202
178
223
84
250
215
Net Income
915
1,035
968
1,099
-3,593
1,045
913
646
1,032
1,082
Net Profit Margin
36.73%
41.69%
38.48%
40.92%
-135.83%
37.71%
31.35%
23.33%
34.84%
35.20%

Vertex Pharmaceuticals Incorporated Annual Profit & Loss

All numbers in Millions USD

Dec 2015
Dec 2016
Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Total Revenue
1,032
1,702
2,488
3,047
4,162
6,205
7,574
8,930
9,869
11,020
Gross Profit
906
1,491
2,213
2,638
3,615
5,469
6,670
7,850
8,607
9,489
Operating Income
-468
9
123
635
1,197
2,856
2,782
4,307
3,832
-232
EBITDA
-411
75
103
706
1,560
3,284
2,917
4,435
4,605
486
Interest Expense
84
81
69
34
58
58
61
54
44
30
Depreciation
-
-
61
72
106
109
125
148
181
207
Income Before Tax
-559
-67
-15
600
1,394
3,116
2,730
4,232
4,379
248
Income Tax Expense
30
16
-107
-1,486
218
405
388
910
760
784
Net Income
-558
-112
263
2,096
1,176
2,711
2,342
3,322
3,619
-535
Net Profit Margin
-54.06%
-6.58%
10.59%
68.80%
28.27%
43.70%
30.92%
37.20%
36.68%
-4.86%

Vertex Pharmaceuticals Incorporated Quarterly Cash Flow

All numbers in Millions USD

Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Net Income
1,035
968
1,099
-3,593
1,045
913
646
1,032
1,082
Operating Cash Flow
1,268
234
1,306
-3,753
1,369
584
818
1,073
1,241
Investing Cash Flow
-117
-886
-2,136
-463
-348
-821
-55
-484
-117
Financing Cash Flow
-165
-119
-357
-358
-387
-391
-680
-349
-1,154
Change in Cash
963
-744
-1,202
-4,578
657
-675
113
296
-34

Vertex Pharmaceuticals Incorporated Annual Cash Flow

All numbers in Millions USD

Dec 2016
Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Net Income
-84
91
2,087
1,176
2,711
2,342
3,322
3,619
-535
Operating Cash Flow
236
844
1,270
1,569
3,253
2,643
4,129
3,537
-492
Investing Cash Flow
104
-437
-202
-1,235
99
-340
-321
-3,141
-3,770
Financing Cash Flow
133
68
-71
126
-505
-1,478
-67
-562
-1,494
Change in Cash
469
481
990
462
2,868
811
3,711
-139
-5,800

Mutual Funds that own Vertex Pharmaceuticals Incorporated Stock

Check out the Mutual Funds with significant holdings in Vertex Pharmaceuticals Incorporated.

Global Institutional Holdings in Vertex Pharmaceuticals Incorporated

Funds
Holdings
Capital World Investors
11.21%
Vanguard Group Inc
9.35%
BlackRock Inc
8.53%
Capital Research Global Investors
6.28%
State Street Corp
4.59%

Vertex Pharmaceuticals Incorporated News & Key Events

  • img

    Today's Timeline - 29 October

    Wed, 06:45 PM

    -

    Vertex Pharmaceuticals expected to report Q3 earnings of $4.55 per share, with revenue forecasted at $3.04 billion.

    Wed, 08:57 PM

    -

    Vertex Pharmaceuticals has a Zacks Rank #3 and an Earnings ESP of +0.57%.

    Thu, 03:20 AM

    -

    Vertex Pharmaceuticals closed at $417.21, down 1.23%, with upcoming earnings announcement on November 3, 2025.

Insights on Vertex Pharmaceuticals Incorporated

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Profit Spike

    img

    Vertex Pharmaceuticals has shown positive profit trends over the last three quarters. The company's net profit has increased from $646.3 million to $1.08 billion, representing an average growth of 21.0% per quarter.

  • imgPOSITIVE IMPACT

    Revenue Rich

    img

    Vertex Pharmaceuticals Incorporated has shown consistent growth in its quarterly revenue over the last three quarters. Revenue increased from $2.77 billion to $3.07 billion, reflecting an average growth rate of 5.1% per quarter.

  • imgPOSITIVE IMPACT

    Price Rise

    img

    In the last 3 months, VRTX stock has moved up by 13.6%

  • imgNO EFFECT

    Against Peers

    img

    In the last 1 year, Insmed Incorporated has given 152.5% return, outperforming this stock by 171.9%

  • imgNO EFFECT

    Against Peers

    img

    In the last 3 years, Insmed Incorporated has given 897.2% return, outperforming this stock by 861.4%

About Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry.
OrganisationVertex Pharmaceuticals Incorporated
Headquarters50 Northern Avenue, Boston, MA, United States, 02210
IndustryHealth Technology
CEODr. Reshma Kewalramani FASN, M.D.
E-voting on sharesClick here to vote

Key Management of Vertex Pharmaceuticals Incorporated

Name

Title

Dr. Jeffrey Marc Leiden M.D., Ph.D.

Executive Chairman

Dr. Reshma Kewalramani FASN, M.D.

CEO, President & Director

Mr. Charles F. Wagner Jr.

Executive VP, COO & CFO

Dr. David M. Altshuler M.D., Ph.D.

Executive VP & Chief Scientific Officer

Ms. Kristen C. Ambrose CPA

Senior VP & Chief Accounting Officer

Ms. Stephanie Franklin

Senior VP & Chief Human Resources Officer

Dr. Ourania Tatsis Ph.D.

Executive VP and Chief Regulatory & Quality Officer

Ms. Susie Lisa C.F.A.

Senior Vice President of Investor Relations

Mr. Jonathan Biller J.D.

Executive VP & Chief Legal Officer

Ms. Nina Devlin

Senior VP & Chief Communications Officer

FAQs

What is Vertex Pharmaceuticals Incorporated share price today?

Vertex Pharmaceuticals Incorporated share price today is $409.4 as on at the close of the market. Vertex Pharmaceuticals Incorporated share today touched a day high of $416.27 and a low of $406.67.

What is the 52 week high and 52 week low for Vertex Pharmaceuticals Incorporated share?

Vertex Pharmaceuticals Incorporated share touched a 52 week high of $519.88 on and a 52 week low of $362.5 on . Vertex Pharmaceuticals Incorporated stock price today i.e. is closed at $409.4,which is 21.25% down from its 52 week high and 12.94% up from its 52 week low.

What is Vertex Pharmaceuticals Incorporated's market capitalisation today?

Vertex Pharmaceuticals Incorporated market capitalisation is $0.11T as on .

How to invest in Vertex Pharmaceuticals Incorporated Stock (VRTX) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Vertex Pharmaceuticals Incorporated on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Vertex Pharmaceuticals Incorporated Shares that will get you 0.0037 shares as per Vertex Pharmaceuticals Incorporated share price of $409.4 per share as on November 8, 2025 at 2:29 am IST.

What is the minimum amount required to buy Vertex Pharmaceuticals Incorporated Stock (VRTX) from India?

Indian investors can start investing in Vertex Pharmaceuticals Incorporated (VRTX) shares with as little as ₹88.66 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹886.60 in Vertex Pharmaceuticals Incorporated stock (as per the Rupee-Dollar exchange rate as on ). Based on Vertex Pharmaceuticals Incorporated share’s latest price of $409.4 as on November 8, 2025 at 2:29 am IST, you will get 0.0244 shares of Vertex Pharmaceuticals Incorporated. Learn more about fractional shares .

What are the returns that Vertex Pharmaceuticals Incorporated has given to Indian investors in the last 5 years?

Vertex Pharmaceuticals Incorporated stock has given 85.89% share price returns and 19.94% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?