Vertex Pharmaceuticals Incorporated share price logo

Vertex Pharmaceuticals Incorporated Share Price

NASDAQ: VRTX

Large Cap

$451.17

-2.83

(-0.62%)

as on

Vertex Pharmaceuticals Incorporated Stock Performance

as on March 24, 2026 at 6:59 am IST

  • Day's Low

    Day's High

    $451.26
    $463.78
    downward going graph

    -0.02%

    Downside

    2.79%

    Upside

    downward going graph

  • 52 Week's Low

    52 Week's High

    $362.50
    $513.98
    downward going graph

    19.65%

    Downside

    13.92%

    Upside

    downward going graph

Vertex Pharmaceuticals Incorporated share price movements today

Previous Close
$454.00
Open
$457.54
Volume
670.5K
Day's Low - High
$451.26 - $463.78
52 Week Low - High
$362.50 - $513.98

Vertex Pharmaceuticals Incorporated Historical Returns

1 Month Return
-5.62 %
3 Month Return
-1.13 %
1 Year Return
-9.78 %
3 Year Return
+ 48.97 %
5 Year Return
+ 112.56 %

Vertex Pharmaceuticals Incorporated Stock Fundamentals & Key Indicators

Check Vertex Pharmaceuticals Incorporated market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$115.3B

EPS (TTM)

19.1584

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.33%

PE Ratio (TTM)

29.67

Industry PE ratio

17.63179487179487

PEG Ratio

2.2178

EBITDA

4.9B

Revenue (TTM)

12.0B

Profit Margin

32.94%

Return On Equity TTM

22.54%

Vertex Pharmaceuticals Incorporated Stock Valuation

Track how Vertex Pharmaceuticals Incorporated P/E has moved over time to understand its valuation trends.

Vertex Pharmaceuticals Incorporated in the last 5 years

  • Overview

  • Trends

Lowest (14.94x)

December 31, 2021

Industry (17.63x)

March 23, 2026

Today (29.67x)

March 23, 2026

Highest (27.20x)

June 30, 2025

LowHigh

Today’s Price to Earnings Ratio: 29.67x

Vertex Pharmaceuticals Incorporated vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Vertex Pharmaceuticals Incorporated with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %
Vertex Pharmaceuticals Incorporated image
Vertex Pharmaceuticals Incorporated
BUY$115.3B112.56%29.6732.94%
Alnylam Pharmaceuticals, Inc. image
Alnylam Pharmaceuticals, Inc.
BUY$41.4B125.13%133.418.45%
Beone Medicines Ltd image
Beone Medicines Ltd
NA$31.6BNA1115.37%
Regeneron Pharmaceuticals, Inc. image
Regeneron Pharmaceuticals, Inc.
BUY$77.5B56.01%17.6731.41%

Stock Returns calculator for Vertex Pharmaceuticals Incorporated Stock including INR - Dollar returns

The Vertex Pharmaceuticals Incorporated stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.

Investment Value

₹1,00,000

  • 1Y

  • 3Y

  • 5Y

  • 7Y

  • 10Y

Vertex Pharmaceuticals Incorporated investment value today

Current value as on today

₹99,580

Returns

₹420

(-0.42%)

Returns from Vertex Pharmaceuticals Incorporated Stock

₹10,340 (-10.34%)

Dollar Returns*

₹9,919 (+9.92%)

Analyst Recommendation on Vertex Pharmaceuticals Incorporated Stock

Based on 38 analysts

BUY

68.42%

Buy

26.32%

Hold

5.26%

Sell

Based on 38 analysts, 68.42% of analysts recommend a 'BUY' rating for Vertex Pharmaceuticals Incorporated. Average target price of $546.52

Vertex Pharmaceuticals Incorporated Share Price Target

Get share price movements and forecasts by analysts on Vertex Pharmaceuticals Incorporated.

What analysts predicted

17.45%UPSIDE

Target Price

$546.52

Current Price

$451.17

Analyzed by

38 Analysts

Target

$546.52

Vertex Pharmaceuticals Incorporated target price $546.52, a slight upside of 17.45% compared to current price of $451.17. According to 38 analysts rating.

Vertex Pharmaceuticals Incorporated Stock’s Investor Sentiment and Interest

Investment in Vertex Pharmaceuticals Incorporated Shares on INDmoney has grown by 29.11% over the past 30 days, indicating increased transactional activity.

Time period: to

Change:29.11% versus previous 30 day period

Search interest for Vertex Pharmaceuticals Incorporated Stock has increased by 23% in the last 30 days, reflecting an upward trend in search activity.

Time period: to

Change:23% versus previous 30 day period

Vertex Pharmaceuticals Incorporated Quarterly Profit & Loss

All numbers in Millions USD

Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Total Revenue
2,483
2,517
2,687
2,645
2,771
2,912
2,770
2,964
3,076
3,227
Gross Profit
2,164
2,149
2,344
2,273
2,379
2,488
2,407
2,557
2,661
2,761
Operating Income
1,038
988
1,139
-3,514
1,116
1,026
630
1,151
1,186
1,300
EBITDA
1,232
1,217
1,343
-3,327
1,284
1,184
781
1,338
1,356
1,353
Interest Expense
10
10
10
9
7
2
3
3
3
3
Depreciation
42
59
53
54
53
46
48
51
54
55
Income Before Tax
1,179
1,147
1,279
-3,391
1,224
1,136
730
1,283
1,298
1,331
Income Tax Expense
143
178
179
202
178
223
84
250
215
139
Net Income
1,035
968
1,099
-3,593
1,045
913
646
1,032
1,082
1,191
Net Profit Margin
41.69%
38.48%
40.92%
-135.83%
37.71%
31.35%
23.33%
34.84%
35.20%
36.91%

Vertex Pharmaceuticals Incorporated Annual Profit & Loss

All numbers in Millions USD

Dec 2016
Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Total Revenue
1,702
2,488
3,047
4,162
6,205
7,574
8,930
9,869
11,020
12,074
Gross Profit
1,491
2,213
2,638
3,615
5,469
6,670
7,850
8,607
9,489
10,267
Operating Income
9
123
635
1,197
2,856
2,782
4,307
3,832
-232
4,760
EBITDA
75
103
706
1,560
3,284
2,917
4,435
4,605
486
4,967
Interest Expense
81
69
34
58
58
61
54
44
30
13
Depreciation
-
61
72
106
109
125
148
181
207
209
Income Before Tax
-67
-15
600
1,394
3,116
2,730
4,232
4,379
248
4,643
Income Tax Expense
16
-107
-1,486
218
405
388
910
760
784
690
Net Income
-112
263
2,096
1,176
2,711
2,342
3,322
3,619
-535
3,953
Net Profit Margin
-6.58%
10.59%
68.80%
28.27%
43.70%
30.92%
37.20%
36.68%
-4.86%
32.74%

Vertex Pharmaceuticals Incorporated Quarterly Cash Flow

All numbers in Millions USD

Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Net Income
968
1,099
-3,593
1,045
913
646
1,032
1,082
1,191
Operating Cash Flow
234
1,306
-3,753
1,369
584
818
1,073
1,241
498
Investing Cash Flow
-886
-2,136
-463
-348
-821
-55
-484
-117
-288
Financing Cash Flow
-119
-357
-358
-387
-391
-680
-349
-1,154
-77
Change in Cash
-744
-1,202
-4,578
657
-675
113
296
-34
140

Vertex Pharmaceuticals Incorporated Annual Cash Flow

All numbers in Millions USD

Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Net Income
91
2,087
1,176
2,711
2,342
3,322
3,619
-535
3,953
Operating Cash Flow
844
1,270
1,569
3,253
2,643
4,129
3,537
-492
3,631
Investing Cash Flow
-437
-202
-1,235
99
-340
-321
-3,141
-3,770
-945
Financing Cash Flow
68
-71
126
-505
-1,478
-67
-562
-1,494
-2,261
Change in Cash
481
990
462
2,868
811
3,711
-139
-5,800
515

Mutual Funds that own Vertex Pharmaceuticals Incorporated Stock

Check out the Mutual Funds with significant holdings in Vertex Pharmaceuticals Incorporated.

Global Institutional Holdings in Vertex Pharmaceuticals Incorporated

Funds
Holdings
NORGES BANK
1.25%
Morgan Stanley - Brokerage Accounts
1.22%
Capital Research Global Investors
6.52%
Capital World Investors
10.04%
ClearBridge Advisors, LLC
1.04%
See all

Vertex Pharmaceuticals Incorporated News & Key Events

  • img

    Today's Timeline - 10 March

    Tue, 10:06 PM

    -

    Vertex Pharmaceuticals shares rose 8% after positive late-stage trial results for IgA nephropathy drug povetacicept.

Insights on Vertex Pharmaceuticals Incorporated

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Revenue Rich

    img

    Vertex Pharmaceuticals Incorporated has shown consistent revenue growth over the last four quarters. The revenue increased from $2.77 billion to $3.22 billion, resulting in an average increase of 5.0% each quarter.

  • imgPOSITIVE IMPACT

    Profit Spike

    img

    Vertex Pharmaceuticals Incorporated has shown strong profit growth over the last four quarters. Their net profit increased from $646.3 million to $1.19 billion, with an average growth of 17.0% each quarter.

  • imgPOSITIVE IMPACT

    Best in 3 Years

    img

    In the last 3 years, VRTX has outperformed top 5 stocks with highest market-cap in its industry

  • imgPOSITIVE IMPACT

    Price Rise

    img

    In the last 6 months, VRTX stock has moved up by 19.8%

  • imgNO EFFECT

    Against Peers

    img

    In the last 1 year, Regeneron Pharmaceuticals, Inc. has given 11.4% return, outperforming this stock by 23.2%

About Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry.
OrganisationVertex Pharmaceuticals Incorporated
Headquarters50 Northern Avenue, Boston, MA, United States, 02210
IndustryHealth Technology
CEODr. Reshma Kewalramani FASN, M.D.
E-voting on sharesClick here to vote

Key Management of Vertex Pharmaceuticals Incorporated

Name

Title

Ms. Joy Liu J.D.

EVP, Chief Legal Officer & Corporate Secretary

Ms. Nina Devlin

Senior VP & Chief Communications Officer

Dr. Reshma Kewalramani FASN, M.D.

CEO, President & Director

Mr. Charles F. Wagner Jr.

Executive VP, COO & CFO

Dr. Ourania Tatsis Ph.D.

Executive VP and Chief Regulatory & Quality Officer

Dr. Mark Bunnage D.Phil

Executive VP & Chief Scientific Officer

Ms. Susie Lisa C.F.A.

Senior Vice President of Investor Relations

Dr. Jeffrey Marc Leiden M.D., Ph.D.

Executive Chairman

Dr. David M. Altshuler M.D., Ph.D.

Executive Officer

Ms. Kristen C. Ambrose CPA

Senior VP & Chief Accounting Officer

FAQs

What is Vertex Pharmaceuticals Incorporated share price today?

Vertex Pharmaceuticals Incorporated share price today is $451.17 as on at the close of the market. Vertex Pharmaceuticals Incorporated share today touched a day high of $463.78 and a low of $451.26.

What is the 52 week high and 52 week low for Vertex Pharmaceuticals Incorporated share?

Vertex Pharmaceuticals Incorporated share touched a 52 week high of $513.98 on and a 52 week low of $362.5 on . Vertex Pharmaceuticals Incorporated stock price today i.e. is closed at $451.17,which is 12.22% down from its 52 week high and 24.46% up from its 52 week low.

What is Vertex Pharmaceuticals Incorporated's market capitalisation today?

Vertex Pharmaceuticals Incorporated market capitalisation is $0.12T as on .

How to invest in Vertex Pharmaceuticals Incorporated Stock (VRTX) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Vertex Pharmaceuticals Incorporated on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Vertex Pharmaceuticals Incorporated Shares that will get you 0.0033 shares as per Vertex Pharmaceuticals Incorporated share price of $451.17 per share as on March 24, 2026 at 1:29 am IST.

What is the minimum amount required to buy Vertex Pharmaceuticals Incorporated Stock (VRTX) from India?

Indian investors can start investing in Vertex Pharmaceuticals Incorporated (VRTX) shares with as little as ₹94.058 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹940.58 in Vertex Pharmaceuticals Incorporated stock (as per the Rupee-Dollar exchange rate as on ). Based on Vertex Pharmaceuticals Incorporated share’s latest price of $451.17 as on March 24, 2026 at 1:29 am IST, you will get 0.0222 shares of Vertex Pharmaceuticals Incorporated. Learn more about fractional shares .

What are the returns that Vertex Pharmaceuticals Incorporated has given to Indian investors in the last 5 years?

Vertex Pharmaceuticals Incorporated stock has given 112.56% share price returns and 29.13% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?