Alnylam Pharma share price logo

Alnylam Pharma

NASDAQ: ALNY

Large Cap

$230.14

+5.54

(+2.47%)

Live

as on

Alnylam Pharma Stock Performance

as on August 19, 2026 at 3:30 am IST

  • Day's Low

    Day's High

    $222.01
    $230.22
    downward going graph

    3.53%

    Downside

    0.03%

    Upside

    downward going graph
  • 52 Week's Low

    52 Week's High

    $197.81
    $495.55
    downward going graph

    14.05%

    Downside

    115.33%

    Upside

    downward going graph

Alnylam Pharma share price movements today

Previous Close
$224.60
Open
$225.85
Volume
467.2K
Market Cap
$30.6B
Day's Low - High
$222.01 - $230.22
52 Week Low - High
$197.81 - $495.55

Alnylam Pharma Historical Returns

1 Month Return
-14.51 %
3 Month Return
-20.33 %
1 Year Return
-49.07 %
3 Year Return
+ 24.34 %
5 Year Return
+ 14.18 %

Alnylam Pharma Stock Fundamentals & Key Indicators

Check Alnylam Pharma market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$30.6B

EPS (TTM)

8.9154

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.00%

PE Ratio (TTM)

39.83

Industry PE ratio

10.197

PEG Ratio

0.4344

EBITDA

1.1B

Revenue (TTM)

4.8B

Profit Margin

16.13%

Return On Equity TTM

96.56%

Alnylam Pharma Stock Valuation

Track how Alnylam Pharma P/E has moved over time to understand its valuation trends.

Alnylam Pharma in the last 5 years

  • Overview

  • Trends

Lowest (-99.61x)

December 31, 2023

Industry (10.20x)

August 17, 2026

Today (39.83x)

August 17, 2026

Highest (124.53x)

September 30, 2025

LowHigh

Today’s Price to Earnings Ratio: 39.83x

Alnylam Pharma vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Alnylam Pharma with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %Dividend Yield %
BUY$30.6B14.18%39.8316.13%NA
BUY$43.7B669.3%NA0.00%NA
BUY$128.2B154.86%29.8286.04%NA
BUY$82.7B24.1%19.2484.86%0.44999999999999996%

Stock Returns calculator for Alnylam Pharma Stock including INR - Dollar returns

The Alnylam Pharma stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.

Investment Value

₹1,00,000

  • 1Y

  • 3Y

  • 5Y

  • 7Y

  • 10Y

Alnylam Pharma investment value today

Current value as on today

₹56,175

Returns

-₹43,825

(-43.83%)

Returns from Alnylam Pharma Stock

-₹48,734 (-48.73%)

Dollar Impact

₹4,908 (+4.91%)

Analyst Recommendation on Alnylam Pharma Stock

Based on 19 analysts

BUY

84.21%

Buy

15.79%

Hold

0.00%

Sell

Based on 19 analysts, 84.21052631578947% of analysts recommend a 'BUY' rating for Alnylam Pharma. Average target price of $372.29

Alnylam Pharma Share Price Target

Get share price movements and forecasts by analysts on Alnylam Pharma.

What analysts predicted

38.18%UPSIDE

Target Price

$372.29

Current Price

$230.14

Analyzed by

19 Analysts

Target

$372.29

Alnylam Pharma target price $372.29, a slight upside of 38.18% compared to current price of $230.14. According to 19 analysts rating.

Indian Investors' Interest in Alnylam Pharma Stock

Investment in Alnylam Pharma Shares on INDmoney has grown by 150.98% in the last 30 days, indicating increased investment activity.

Time period: to

Change:150.98% versus previous 30 day period

Search interest for Alnylam Pharma Stock has increased by 171% in the last 30 days, reflecting an upward trend in search activity.

Time period: to

Change:171% versus previous 30 day period

Alnylam Pharma Quarterly Profit & Loss

All numbers in Millions USD

Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Mar 2026
Jun 2026
Total Revenue
494
659
500
593
594
773
1,249
1,097
1,167
1,290
Gross Profit
428
591
415
490
523
630
1,051
829
956
992
Operating Income
-43
48
-76
-105
18
-16
367
131
268
231
EBITDA
-14
37
-60
-140
11
18
297
303
304
244
Interest Expense
35
33
34
38
38
40
44
129
69
82
Depreciation
25
24
27
-20
14
13
13
13
13
13
Income Before Tax
-63
-11
-108
-193
-41
-35
238
161
221
177
Income Tax Expense
2
5
2
-110
15
30
-12
-25
-15
13
Net Income
-65
-16
-111
-83
-57
-66
251
186
205
164
Net Profit Margin
-13.34%
-2.56%
-22.27%
-14.12%
-9.67%
-8.57%
20.10%
16.99%
17.65%
12.74%

Alnylam Pharma Annual Profit & Loss

All numbers in Millions USD

Dec 2016
Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Total Revenue
47
89
74
219
492
844
1,037
1,828
2,248
3,713
Gross Profit
47
89
73
194
414
704
868
1,517
1,924
3,036
Operating Income
-424
-500
-814
-939
-828
-708
-785
-282
-176
501
EBITDA
-409
-486
-754
-885
-736
-661
-926
-258
-178
631
Interest Expense
8
12
29
108
84
143
155
121
141
252
Depreciation
-
13
6
54
74
89
85
97
56
55
Income Before Tax
-410
-490
-760
-885
-855
-852
-1,126
-433
-377
323
Income Tax Expense
-23
-25
0
0
2
0
4
6
-99
9
Net Income
-410
-490
-761
-886
-858
-852
-1,131
-440
-278
313
Net Profit Margin
-869.63%
-545.95%
-1016.58%
-403.24%
-174.15%
-101.01%
-109.04%
-24.08%
-12.37%
8.45%

Alnylam Pharma Quarterly Cash Flow

All numbers in Millions USD

Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Mar 2026
Jun 2026
Net Income
-16
-111
-83
-57
-66
251
186
205
164
Operating Cash Flow
124
43
-94
-118
153
325
163
70
75
Investing Cash Flow
33
-30
-52
113
-141
501
-37
-25
-363
Financing Cash Flow
131
102
30
44
53
-448
45
15
23
Change in Cash
286
131
-133
53
93
376
166
53
-267

Alnylam Pharma Annual Cash Flow

All numbers in Millions USD

Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Net Income
-490
-761
-886
-858
-852
-1,131
-440
-278
313
Operating Cash Flow
-382
-562
-278
-614
-641
-541
104
-8
524
Investing Cash Flow
-290
272
-417
-435
-273
169
-336
-116
436
Financing Cash Flow
1,124
65
823
994
1,247
425
172
294
-305
Change in Cash
451
-224
126
-50
323
46
-53
153
690

Mutual Funds that own Alnylam Pharma Stock

Check out the Mutual Funds with significant holdings in Alnylam Pharma.

Funds
Holdings
Shares Held
VANGUARD INDEX FUNDS
8.437275%
11289843
Growth Fund of America
5.99699%
8024520
AMCAP Fund
2.798508%
3744659
JPMorgan Trust II
2.045879%
2737573
Fidelity Securities Fund
1.893072%
2533104

Global Institutional Holdings in Alnylam Pharma

Funds
Holdings
Vanguard
9.34%
iShares
4.82%
Invesco
3.44%
John A. Gunn
1.46%
Capital Group
0.61%

Alnylam Pharma News & Key Events

  • img

    Today's Timeline - 30 July

    Fri, 05:52 AM

    -

    Alnylam's Q2 2026 earnings call highlights record AMVUTTRA sales exceeding $1 billion, but lowers TTR revenue guidance.

Insights on Alnylam Pharma

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Revenue Rich

    img

    Revenue is up for the last 3 quarters, 1.09B → 1.29B (in $), with an average increase of 7.8% per quarter

  • imgNO EFFECT

    Against Peers

    img

    In the last 3 years, Revolution Medicines, Inc. Common Stock has given 615.7% return, outperforming this stock by 595.0%

  • imgNO EFFECT

    Against Peers

    img

    In the last 1 year, Revolution Medicines, Inc. Common Stock has given 481.6% return, outperforming this stock by 532.4%

  • imgNEGATIVE IMPACT

    Profit Down

    img

    Netprofit is down for the last 2 quarters, 205.99M → 164.49M (in $), with an average decrease of 20.2% per quarter

  • imgNEGATIVE IMPACT

    Price Dip

    img

    In the last 1 month, ALNY stock has moved down by -16.0%

About Alnylam Pharma

Alnylam Pharmaceuticals, Inc. discovers, develops, manufactures, and commercializes therapeutics based on ribonucleic acid interference in the United States, Europe, and internationally. The company offers ONPATTRO for hereditary transthyretin-mediated (hATTR) amyloidosis; AMVUTTRA for ATTR and hATTR amyloidosis; Leqvio for hypercholesterolemia; Qfitlia for hemophilia A or B; GIVLAARI for acute hepatic porphyria; and OXLUMO for primary hyperoxaluria type 1. It also develops a range of products in Phase 3 trial, such as Nucresiran for ATTR amyloidosis; Zilebesiran for hypertension; Cemdisiran for myasthenia gravis, paroxysmal nocturnal hemoglobinuria, and geographic atrophy; and Elebsiran for hepatitis D virus infections. In addition, the company is developing various products in Phase 2 trial, including Rapirosiran for metabolic dysfunction-associated steatohepatitis; ALN-ANG3 for diabetic kidney disease; ALN-4324 for type 2 diabetes mellitus; Mivelsiran for cerebral amyloid angiopathy, as well as in Phase 1 trial for Alzheimer's disease; and ALN-6400 for bleeding disorders. Further, it develops a range of products in Phase 1 trial, such as ALN-2232 for obesity and weight management; ALN-PNP for non-alcoholic fatty liver disease; ALN-APOC3 for dyslipidemia; ALN-CIDEB for metabolic dysfunction-associated steatohepatitis; ALN-HTT02 for Huntington's disease; ALN-5288 for Alzheimer's disease; ALN-SOD for SOD1 amyotrophic lateral sclerosis; ALN-SNCA for Parkinson's disease; AG-236 for polycythemia vera; ALN-CFB for paroxysmal nocturnal hemoglobinuria; ALN-BCAT for hepatocellular carcinoma; and ALN-4285, ALN-4915, and ALN-F1202 for healthy volunteers. The company has collaborations with Regeneron Pharmaceuticals, Inc.; Roche Holding AG; Sanofi S.A.; Novartis AG; PeptiDream, Inc; Dicerna Pharmaceuticals, Inc.; and Ionis Pharmaceuticals, Inc. Alnylam Pharmaceuticals, Inc. was founded in 2002 and is headquartered in Cambridge, Massachusetts.
OrganisationAlnylam Pharma
Headquarters675 West Kendall Street, Cambridge, MA, United States, 02142
IndustryBiotechnology
CEODr. Yvonne L. Greenstreet M.B.A., M.D.
E-voting on sharesClick here to vote

Key Management of Alnylam Pharma

Name

Title

Mr. Jeffrey V. Poulton M.B.A.

CFO & Executive VP

Dr. Pushkal P. Garg M.D.

Executive VP & Chief Research & Development Officer

Ms. Melissa McLaughlin M.B.A.

Chief Human Resources Officer

Dr. Yvonne L. Greenstreet M.B.A., M.D.

CEO & Director

Dr. Phillip A. Sharp Ph.D.

Co-Founder, Member of the Scientific Advisory Board

Dr. Kevin Joseph Fitzgerald Ph.D.

Executive VP, Chief Scientific Officer and Head of Early Research & Early Development

Mr. Joshua Brodsky

Vice President of Investor Relations

Mr. Piyush Sharma J.D.

Chief Ethics & Compliance Officer

Mr. Bryan Andrew Supran J.D.

Chief Legal Officer

Mr. Timothy J. Maines

Chief Technical Operations & Quality Officer

FAQs

What is Alnylam Pharma share price today?

Alnylam Pharma share price today is $230.14 as on . Alnylam Pharma share today touched a day high of $230.22 and a low of $222.01.

What is the 52 week high and 52 week low for Alnylam Pharma share?

Alnylam Pharma share touched a 52 week high of $495.55 on and a 52 week low of $197.81 on . Alnylam Pharma stock price today i.e. is trending at $230.14,which is 53.56% down from its 52 week high and 16.34% up from its 52 week low.

What is Alnylam Pharma's market capitalisation today?

Alnylam Pharma market capitalisation is $0.03T as on .

How to invest in Alnylam Pharma Stock (ALNY) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Alnylam Pharma on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Alnylam Pharma Shares that will get you 0.0065 shares as per Alnylam Pharma share price of $230.14 per share as on August 18, 2026 at 10:00 pm IST.

What is the minimum amount required to buy Alnylam Pharma Stock (ALNY) from India?

Indian investors can start investing in Alnylam Pharma (ALNY) shares with as little as ₹95.67 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹956.70 in Alnylam Pharma stock (as per the Rupee-Dollar exchange rate as on ). Based on Alnylam Pharma share’s latest price of $230.14 as on August 18, 2026 at 10:00 pm IST, you will get 0.0435 shares of Alnylam Pharma. Learn more about fractional shares .

What are the returns that Alnylam Pharma has given to Indian investors in the last 5 years?

Alnylam Pharma stock has given 14.18% share price returns and 28.34% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?