Septerna, Inc. (SEPN) Live Share Price, Invest From India

Septerna, Inc. Stock Performance

as on October 17, 2026 at 2:16 pm IST

Day's Low
Day's High
$35.09
Day's Price Range
$37.47
$36.35
3.47%
Downside
3.08%
Upside
52 Week's Low
52 Week's High
$17.55
52-Week Price Range
$51.10
$36.35
51.72%
Downside
40.58%
Upside

Septerna, Inc. share price movements today

Previous Close: $37.45
Open: $37.47
Volume: 344.7K
Market Cap: $1.7B
Day's Low - High: $35.09 - $37.47
52 Week Low - High: $17.55 - $51.10

Septerna, Inc. Historical Returns

1 Month Return: -7.97 %
3 Month Return: + 8.83 %
1 Year Return: + 64.78 %
3 Year Return: 0 %
5 Year Return: 0 %

Septerna, Inc. Stock Fundamentals & Key Indicators

Check Septerna, Inc. market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$1.7B

EPS (TTM)

-0.54

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.00%

PE Ratio (TTM)

-69.35

Industry PE ratio

-6.86

PEG Ratio

-0.39

EBITDA

-39.3M

Revenue (TTM)

98.9M

Profit Margin

99.57%

Return On Equity TTM

-6.31%

Septerna, Inc. vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Septerna, Inc. with its industry peers.

Company	Analyst View	Market Cap	5 Years Return %	PE Ratio	Profit Margin %	Dividend Yield %
Septerna, Inc.	StrongBuy	$1.7B	NA	-69.35	99.57%	0.00%
Moderna	Neutral	$94.4B	-32.76%	-29.64	-12.57%	0.00%
Vertex Pharmaceuticals	StrongBuy	$128.9B	174.93%	29.37	86.04%	0.00%
Regeneron	Buy	$80.1B	42.93%	19.01	84.86%	0.46%

Stock Returns calculator for Septerna, Inc. Stock including INR - Dollar returns

The Septerna, Inc. stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.

Investment Value

₹1,00,000

Septerna, Inc. investment value today

Current value as on today

₹1,78,063

Returns

₹78,063

(+78.06%)

Returns from Septerna, Inc. Stock

₹64,778 (+64.78%)

Dollar Impact

₹13,285 (+13.29%)

Analyst Recommendation on Septerna, Inc. Stock

Based on 9 analysts

BUY

100.00%

Buy

0.00%

Hold

0.00%

Sell

Based on 9 analysts, 100% of analysts recommend a 'BUY' rating for Septerna, Inc.. Average target price of $52.875

Septerna, Inc. Share Price Target

Get share price movements and forecasts by analysts on Septerna, Inc..

Current Price

$36.35

Analyzed by

9 Analysts

High

$60

Low

$46

Septerna, Inc. target price $0, a slight upside of 0% compared to current price of $36.35. According to 9 analysts rating.

Indian Investors' Interest in Septerna, Inc. Stock

Search interest for Septerna, Inc. Stock has decreased by -55% in the last 30 days, reflecting a downward trend in search activity.

Time period: September 19, 2026 to October 19, 2026

Change:-55% versus previous 30 day period

Septerna, Inc. Quarterly Profit & Loss

All numbers in Millions USD

	Dec 2023	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025	Sep 2025	Dec 2025	Mar 2026	Jun 2026
Total Revenue	0	0	0	0	0	0	21	24	26	26
Gross Profit	0	0	0	0	0	0	21	24	26	26
Operating Income	34	-18	-22	-24	-25	-28	2	-16	-13	-16
EBITDA	-13	-16	-20	-20	-21	-24	-9	-10	-7	-11
Interest Expense	-	-	-	-	-	-	-	-	-	-
Depreciation	0	0	0	0	0	0	0	0	0	0
Income Before Tax	35	-16	-20	-20	-21	-24	8	-10	-8	-12
Income Tax Expense	0	0	0	0	-	-	-	0	0	0
Net Income	34	-16	-20	-20	-21	-24	8	-10	-8	-13
Net Profit Margin	100.00%	100.00%	100.00%	100.00%	100.00%	100.00%	100.00%	100.00%	98.41%	100.00%

Septerna, Inc. Annual Profit & Loss

All numbers in Millions USD

	Dec 2022	Dec 2023	Dec 2024	Dec 2025
Total Revenue	-	0	1	45
Gross Profit	-	0	1	45
Operating Income	-27	2	-80	-80
EBITDA	-27	-44	-70	-47
Interest Expense	-	-	-	-
Depreciation	0	0	1	1
Income Before Tax	-27	4	-72	-48
Income Tax Expense	-	0	0	0
Net Income	-27	4	-71	-48
Net Profit Margin	0.00%	100.00%	100.00%	100.00%

Septerna, Inc. Quarterly Cash Flow

All numbers in Millions USD

	Dec 2023	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025	Sep 2025	Dec 2025	Mar 2026	Jun 2026
Net Income	34	-16	-20	-20	-21	-24	8	-10	-8	-13
Operating Cash Flow	-8	-12	-16	-20	-23	-20	168	-14	-25	-22
Investing Cash Flow	-1	-12	-24	-133	-4	0	-38	-185	-23	18
Financing Cash Flow	-	74	-1	304	0	0	0	1	0	16
Change in Cash	-10	49	-42	149	-28	-20	130	-199	-49	13

Septerna, Inc. Annual Cash Flow

All numbers in Millions USD

	Dec 2022	Dec 2023	Dec 2024	Dec 2025
Net Income	-27	4	-71	-48
Operating Cash Flow	-23	-38	-67	110
Investing Cash Flow	-1	22	-160	-229
Financing Cash Flow	30	74	377	1
Change in Cash	5	57	149	-117

Global Institutional Holdings in Septerna, Inc.

Check out the Institutions with significant holdings in Septerna, Inc..

Funds	Holdings
Peter Kolchinsky	14.99%
Richard Driehaus	9.50%
Vanguard	3.11%
iShares	2.63%
Theofanis Kolokotrones	2.50%

See all

Insights on Septerna, Inc.

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

POSITIVE IMPACT
Price Rise
In the last 6 months, SEPN stock has moved up by 39.1%
NO EFFECT
Against Peers
In the last 1 year, Moderna, Inc. Common Stock has given 738.2% return, outperforming this stock by 673.4%

About Septerna, Inc.

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric modulator (NAM) for chronic spontaneous urticaria and other mast cell diseases; and TSHR Program, an oral small molecule TSHR NAM for graves’ disease and thyroid eye disease. In addition, it focuses on other therapeutic areas, including neurology, women’s health, cardiovascular disease, and respiratory disease. It has global collaboration and license agreement with Novo Nordisk to discover, develop and commercialize multiple potential oral small molecule therapies for metabolic-related diseases based on certain specified molecular targets. The company was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. Septerna, Inc. was incorporated in 2019 and is headquartered in South San Francisco, California.

Organisation	Septerna, Inc.
Headquarters	250 East Grand Avenue, South San Francisco, CA, 94080, US
Industry	Biotechnology
CEO	Jeffrey T. Finer

Key Management of Septerna, Inc.

Name	Title
Ms. Samira Shaikhly	Chief People Officer
Dr. Jeffrey T. Finer M.D., Ph.D.	Co-Founder, CEO & Director
Mr. Gilbert M. Labrucherie C.F.A., J.D.	Chief Financial Officer
Dr. Robert J. Lefkowitz M.D.	Co-Founder and Member of Cross-Functional Scientific & Drug Discovery Advisory Board
Dr. Arthur Christopoulos BPHARM, Ph.D.	Co-Founder and Member of Cross-Functional Scientific & Drug Discovery Advisory Board
Mr. Richard Hansen Ph.D.	Vice President of Technology
Ms. Elizabeth P. Bhatt M.B.A., M.S.	President & COO
Dr. Patrick Sexton Ph.D.	Co-Founder and Member of Cross-Functional Scientific & Drug Discovery Advisory Board
Mr. Mark A. Wilson J.D.	Chief Legal Officer
Mr. George Xu Ph.D.	Senior Director of Corporate Development & Portfolio Strategy

FAQs

What is Septerna, Inc. share price today?

Septerna, Inc. share price today is $36.35 as on October 17, 2026 at 8:46 am IST at the close of the market. Septerna, Inc. share today touched a day high of $37.47 and a low of $35.09.

What is the 52 week high and 52 week low for Septerna, Inc. share?

Septerna, Inc. share touched a 52 week high of $51.10 on August 12, 2026 and a 52 week low of $17.55 on November 7, 2025. Septerna, Inc. stock price today i.e. October 17, 2026 at 8:46 am IST is closed at $36.35,which is 28.86% down from its 52 week high and 107.12% up from its 52 week low.

What is Septerna, Inc.'s market capitalisation today?

Septerna, Inc. market capitalisation is $0.00T as on October 17, 2026 at 8:46 am IST.

How to invest in Septerna, Inc. Stock (SEPN) from India?

Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
Step 2: Search for Septerna, Inc. on INDmoney app. Click on Buy button.

What is the minimum amount required to buy Septerna, Inc. Stock (SEPN) from India?

Indian investors can start investing in Septerna, Inc. (SEPN) shares with as little as ₹94.959999084473 or $1 (as of October 19, 2026 at 7:46 am IST) using the INDmoney app.
For example: If you want to invest $10 or ₹949.60 in Septerna, Inc. stock (as per the Rupee-Dollar exchange rate as on October 19, 2026 at 7:46 am IST). Based on Septerna, Inc. share’s latest price of $36.35 as on October 17, 2026 at 8:46 am IST, you will get 0.2751 shares of Septerna, Inc.. Learn more about fractional shares .