Septerna Inc. share price logo

Septerna Inc. Share Price

NASDAQ: SEPN

Small Cap

$24.81

-0.37

(-1.47%)

as on

Septerna Inc. Stock Performance

as on April 7, 2026 at 6:59 am IST

  • Day's Low

    Day's High

    $24.38
    $25.48
    downward going graph

    1.73%

    Downside

    2.70%

    Upside

    downward going graph

  • 52 Week's Low

    52 Week's High

    $4.66
    $32.63
    downward going graph

    81.22%

    Downside

    31.52%

    Upside

    downward going graph

Septerna Inc. share price movements today

Previous Close
$25.18
Open
$24.88
Volume
250.5K
Day's Low - High
$24.38 - $25.48
52 Week Low - High
$4.66 - $32.63

Septerna Inc. Historical Returns

1 Month Return
-12.51 %
3 Month Return
-1.06 %
1 Year Return
+ 359.49 %
3 Year Return
0 %
5 Year Return
0 %

Septerna Inc. Stock Fundamentals & Key Indicators

Check Septerna Inc. market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$1.1B

EPS (TTM)

-1.1931

Dividend Yield

0.00%

PE Ratio (TTM)

0

PEG Ratio

0

Return On Equity TTM

-12.19%

Septerna Inc. vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Septerna Inc. with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %
Septerna Inc. image
Septerna Inc.
NA$1.1BNANA-106.37%
Alnylam Pharmaceuticals, Inc. image
Alnylam Pharmaceuticals, Inc.
BUY$42.3B124.53%136.858.45%
Vertex Pharmaceuticals Incorporated image
Vertex Pharmaceuticals Incorporated
BUY$111.4B103.77%28.6632.94%
Beone Medicines Ltd image
Beone Medicines Ltd
NA$35.7BNA126.855.37%
Regeneron Pharmaceuticals, Inc. image
Regeneron Pharmaceuticals, Inc.
BUY$80.5B59.16%18.3831.41%

Stock Returns calculator for Septerna Inc. Stock including INR - Dollar returns

The Septerna Inc. stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.

Investment Value

₹1,00,000

  • 1Y

Septerna Inc. investment value today

Current value as on today

₹4,90,580

Returns

₹3,90,580

(+390.58%)

Returns from Septerna Inc. Stock

₹3,52,737 (+352.74%)

Dollar Impact

₹37,843 (+37.84%)

Septerna Inc. Stock’s Investor Sentiment and Interest

Search interest for Septerna Inc. Stock has increased by 63% in the last 30 days, reflecting an upward trend in search activity.

Time period: to

Change:63% versus previous 30 day period

Septerna Inc. Quarterly Profit & Loss

All numbers in Millions USD

Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Total Revenue
0
0
0
0
0
0
0
0
21
24
Gross Profit
0
0
0
0
0
0
0
0
21
24
Operating Income
-12
34
-15
-18
-22
-24
-25
-28
2
-16
EBITDA
-11
-13
-15
-17
-22
-24
-25
-28
-9
-15
Interest Expense
-
-
-
-
-
-
-
-
-
-
Depreciation
0
0
0
0
0
0
0
0
0
0
Income Before Tax
-10
35
-14
-16
-20
-20
-21
-24
8
-10
Income Tax Expense
-
0
0
0
0
0
-
-
-
0
Net Income
-10
34
-14
-16
-20
-20
-21
-24
8
-10
Net Profit Margin
-33166.67%
29571.19%
-4468.77%
-4443.51%
-11660.80%
-9749.06%
-9806.39%
-20872.27%
38.02%
-44.52%

Septerna Inc. Annual Profit & Loss

All numbers in Millions USD

Dec 2022
Dec 2023
Dec 2024
Dec 2025
Total Revenue
-
0
1
45
Gross Profit
-
0
1
45
Operating Income
-27
2
-80
-80
EBITDA
-27
-44
-79
-79
Interest Expense
-
-
-
-
Depreciation
0
0
1
1
Income Before Tax
-27
4
-72
-48
Income Tax Expense
-
0
0
0
Net Income
-27
4
-71
-48
Net Profit Margin
0.00%
2768.21%
-6678.88%
-106.37%

Septerna Inc. Quarterly Cash Flow

All numbers in Millions USD

Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Net Income
34
-14
-16
-20
-20
-21
-24
8
-10
Operating Cash Flow
-8
-16
-12
-16
-20
-23
-20
168
-14
Investing Cash Flow
-1
9
-12
-24
-133
-4
0
-38
-185
Financing Cash Flow
-
-
74
-1
304
0
0
0
1
Change in Cash
-10
-7
131
-42
149
-28
-20
130
-199

Septerna Inc. Annual Cash Flow

All numbers in Millions USD

Dec 2023
Dec 2024
Dec 2025
Net Income
4
-71
-48
Operating Cash Flow
-38
-67
110
Investing Cash Flow
22
-160
-229
Financing Cash Flow
74
377
1
Change in Cash
57
149
-117

Insights on Septerna Inc.

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Best in 1 Year

    img

    In the last 1 year, SEPN has outperformed top 5 stocks with highest market-cap in its industry

  • imgPOSITIVE IMPACT

    Price Rise

    img

    In the last 1 year, SEPN stock has moved up by 368.0%

About Septerna Inc.

Septerna, Inc. is a clinical-stage biotechnology company. The Company is developing G protein-coupled receptor (GPCR) oral small-molecule drug discovery powered by its proprietary Native Complex Platform. Its pipeline of product candidates is focused on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic diseases. Its industrial-scale Native Complex Platform is designed to target certain GPCRs for the first time, uncover novel binding pockets for validated receptors, and pursue a wide spectrum of pharmacologies, including agonists, antagonists, and allosteric modulators, to achieve desired therapeutic effects. It is advancing a deep portfolio of oral small molecule GPCR-targeted programs with novel mechanistic approaches to treat diseases across multiple therapeutic areas for patients with unmet needs. It is focused on therapeutic areas, such as neurology, women’s health, cardiovascular, and respiratory disease.
OrganisationSepterna Inc.
Headquarters250 East Grand Avenue, South San Francisco, CA, United States, 94080
CEODr. Jeffrey T. Finer M.D., Ph.D.
E-voting on sharesClick here to vote

Key Management of Septerna Inc.

Name

Title

Dr. Arthur Christopoulos BPHARM, Ph.D.

Co-Founder and Member of Cross-Functional Scientific & Drug Discovery Advisory Board

Dr. Patrick Sexton Ph.D.

Co-Founder and Member of Cross-Functional Scientific & Drug Discovery Advisory Board

Mr. Gilbert M. Labrucherie C.F.A., J.D.

Chief Financial Officer

Mr. George Xu Ph.D.

Senior Director of Corporate Development & Portfolio Strategy

Dr. Jeffrey T. Finer M.D., Ph.D.

Co-Founder, CEO & Director

Ms. Elizabeth P. Bhatt M.B.A., M.S.

President & COO

Mr. Richard Hansen Ph.D.

Vice President of Technology

Mr. Mark A. Wilson J.D.

Chief Legal Officer

Dr. Jae B. Kim FACC, M.D.

Chief Medical Officer

Dr. Robert J. Lefkowitz M.D.

Co-Founder and Member of Cross-Functional Scientific & Drug Discovery Advisory Board

FAQs

What is Septerna Inc. share price today?

Septerna Inc. share price today is $24.81 as on at the close of the market. Septerna Inc. share today touched a day high of $25.48 and a low of $24.38.

What is the 52 week high and 52 week low for Septerna Inc. share?

Septerna Inc. share touched a 52 week high of $32.63 on and a 52 week low of $4.66 on . Septerna Inc. stock price today i.e. is closed at $24.81,which is 23.97% down from its 52 week high and 432.40% up from its 52 week low.

What is Septerna Inc.'s market capitalisation today?

Septerna Inc. market capitalisation is $0.00T as on .

How to invest in Septerna Inc. Stock (SEPN) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Septerna Inc. on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Septerna Inc. Shares that will get you 0.0605 shares as per Septerna Inc. share price of $24.81 per share as on April 7, 2026 at 1:29 am IST.

What is the minimum amount required to buy Septerna Inc. Stock (SEPN) from India?

Indian investors can start investing in Septerna Inc. (SEPN) shares with as little as ₹93.06 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹930.60 in Septerna Inc. stock (as per the Rupee-Dollar exchange rate as on ). Based on Septerna Inc. share’s latest price of $24.81 as on April 7, 2026 at 1:29 am IST, you will get 0.4031 shares of Septerna Inc.. Learn more about fractional shares .