OnKure Therapeutics (OKUR) Live Share Price, Invest From India

OnKure Therapeutics Stock Performance

as on August 22, 2026 at 2:16 pm IST

Day's Low
Day's High
$3.90
Day's Price Range
$4.07
$3.94
1.02%
Downside
3.30%
Upside
52 Week's Low
52 Week's High
$2.23
52-Week Price Range
$5.38
$3.94
43.40%
Downside
36.55%
Upside

OnKure Therapeutics share price movements today

Previous Close: $3.93
Open: $3.91
Volume: 108.2K
Market Cap: $161.6M
Day's Low - High: $3.90 - $4.07
52 Week Low - High: $2.23 - $5.38

OnKure Therapeutics Historical Returns

1 Month Return: -5 %
3 Month Return: + 26.27 %
1 Year Return: + 57.71 %
3 Year Return: 0 %
5 Year Return: 0 %

OnKure Therapeutics Stock Fundamentals & Key Indicators

Check OnKure Therapeutics market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$161.6M

EPS (TTM)

-3.5

Dividend Yield

0.00%

PE Ratio (TTM)

-1.11

Industry PE ratio

-1.5966015625

PEG Ratio

-0.036474845598009356

Return On Equity TTM

-49.02%

OnKure Therapeutics Stock Valuation

Track how OnKure Therapeutics P/E has moved over time to understand its valuation trends.

OnKure Therapeutics in the last 5 years

Overview
Trends

Lowest (-10.53x)

December 31, 2022

Industry (-1.60x)

December 31, 2025

Today (-0.66x)

December 31, 2025

Highest (-0.66x)

December 31, 2025

LowHigh

Today’s Price to Earnings Ratio: -0.66x

OnKure Therapeutics vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of OnKure Therapeutics with its industry peers.

Company	Analyst View	Market Cap	5 Years Return %	PE Ratio	Profit Margin %	Dividend Yield %
OnKure Therapeutics	StrongBuy	$161.6M	NA	-1.11	0.00%	NA
Revolution Medicines	BUY	$43.7B	669.3%	NA	0.00%	NA
Vertex Pharmaceuticals	BUY	$128.2B	154.86%	29.82	86.04%	NA
Moderna	BUY	$25.3B	-84.24%	-7.98	-12.57%	NA
Regeneron	BUY	$82.7B	24.1%	19.24	84.86%	0.44999999999999996%

Stock Returns calculator for OnKure Therapeutics Stock including INR - Dollar returns

The OnKure Therapeutics stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.

Investment Value

₹1,00,000

OnKure Therapeutics investment value today

Current value as on today

₹1,70,132

Returns

₹70,132

(+70.13%)

Returns from OnKure Therapeutics Stock

₹55,731 (+55.73%)

Dollar Impact

₹14,401 (+14.4%)

Analyst Recommendation on OnKure Therapeutics Stock

Based on 4 analysts

BUY

75.00%

Buy

25.00%

Hold

0.00%

Sell

Based on 4 analysts, 75% of analysts recommend a 'BUY' rating for OnKure Therapeutics. Average target price of $22.33

Indian Investors' Interest in OnKure Therapeutics Stock

Search interest for OnKure Therapeutics Stock has decreased by -38% in the last 30 days, reflecting a downward trend in search activity.

Time period: July 25, 2026 to August 24, 2026

Change:-38% versus previous 30 day period

OnKure Therapeutics Quarterly Profit & Loss

All numbers in Millions USD

	Mar 2024	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025	Sep 2025	Dec 2025	Mar 2026	Jun 2026
Total Revenue	-	-	-	-	-	-	-	-	-	-
Gross Profit	-	-	0	0	-	-	-	-	0	-
Operating Income	-9	-14	-4	-33	-17	-16	-15	-14	-15	-16
EBITDA	-9	-13	-3	-31	-15	-15	-14	-13	-14	-15
Interest Expense	-	0	-	-	-	-	0	0	-	-
Depreciation	0	0	0	0	0	0	0	0	0	-
Income Before Tax	-9	-14	-3	-35	-15	-15	-14	-13	-15	-15
Income Tax Expense	-	-	-	-	-	-	-	-	-	-
Net Income	-9	-14	-3	-35	-15	-15	-14	-13	-15	-15
Net Profit Margin	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

OnKure Therapeutics Annual Profit & Loss

All numbers in Millions USD

	Dec 2020	Dec 2021	Dec 2022	Dec 2023	Dec 2024	Dec 2025
Total Revenue	-	-	-	-	-	-
Gross Profit	0	0	-	-	-	0
Operating Income	-19	-39	-29	-36	-54	-62
EBITDA	-19	-39	-29	-34	-51	-58
Interest Expense	-	-	-	-	0	-
Depreciation	0	0	0	0	0	0
Income Before Tax	-19	-39	-29	-35	-52	-59
Income Tax Expense	-	-	-	-	-	-
Net Income	-19	-39	-29	-35	-52	-59
Net Profit Margin	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

OnKure Therapeutics Quarterly Cash Flow

All numbers in Millions USD

	Mar 2024	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025	Sep 2025	Dec 2025	Mar 2026	Jun 2026
Net Income	-9	-14	-11	-35	-15	-15	-14	-13	-15	-15
Operating Cash Flow	-10	-6	-10	-21	-14	-13	-13	-11	-12	-10
Investing Cash Flow	0	0	0	-45	0	0	0	0	0	-9
Financing Cash Flow	0	5	0	114	0	-	-	0	145	-5
Change in Cash	-10	0	-10	50	-14	-13	-13	-11	133	-25

OnKure Therapeutics Annual Cash Flow

All numbers in Millions USD

	Dec 2020	Dec 2021	Dec 2022	Dec 2023	Dec 2024	Dec 2025
Net Income	-19	-39	-29	-35	-52	-59
Operating Cash Flow	-18	-37	-26	-34	-51	-51
Investing Cash Flow	7	-23	-1	0	15	0
Financing Cash Flow	47	132	26	53	116	0
Change in Cash	36	71	-1	18	80	-51

Mutual Funds that own OnKure Therapeutics Stock

Check out the Mutual Funds with significant holdings in OnKure Therapeutics.

Funds	Holdings	Shares Held
VANGUARD INDEX FUNDS	1.438345%	582477
Fidelity Concord Street Trust	0.164291%	66532
Bridgeway Funds, Inc.	0.040233%	16293
TIAA-CREF Funds	0.029407%	11909
DFA INVESTMENT DIMENSIONS GROUP INC	0.006931%	2807

See all

Global Institutional Holdings in OnKure Therapeutics

Funds	Holdings
Peter Kolchinsky	9.87%
Vanguard	3.93%
iShares	2.16%
Scott Kapnick	1.34%
Dennis J Purcell	0.22%

See all

Insights on OnKure Therapeutics

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

POSITIVE IMPACT
Price Rise
In the last 6 months, OKUR stock has moved up by 60.8%
NO EFFECT
Against Peers
In the last 1 year, Revolution Medicines, Inc. Common Stock has given 466.0% return, outperforming this stock by 426.8%
NO EFFECT
Against Peers
In the last 3 years, Revolution Medicines, Inc. Common Stock has given 570.7% return, outperforming this stock by 664.6%

About OnKure Therapeutics

OnKure Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision medicines that target biologically validated drivers of cancers and other diseases. Its lead product candidate includes OKI-219, a selective inhibitor of phosphoinositide 3-kinase alpha (PI3Ka) harboring the H1047R mutation that is in Phase 1 clinical trial for the treatment of solid tumors, including breast cancer. The company was founded in 2011 and is headquartered in Boulder, Colorado.

Organisation	OnKure Therapeutics
Headquarters	6707 Winchester Circle, Boulder, CO, United States, 80301
Industry	Biotechnology
CEO	Dr. Nicholas A. Saccomano Ph.D.
E-voting on shares	Click here to vote

Key Management of OnKure Therapeutics

Name	Title
Mr. Rogan P. Nunn J.D.	General Counsel & Secretary
Dr. James Blake Ph.D.	Senior Vice President of Computational Drug Discovery
Dr. Kevin S. Litwiler Ph.D.	Senior Vice President of DMPK & Clinical Pharmacology
Dr. Nicholas A. Saccomano Ph.D.	President, CEO & Director
Mr. Jason A. Leverone CPA	Chief Financial Officer
Dr. Isaac Manke Ph.D.	Senior VP of Business Development & Director
Dr. Samuel Agresta M.D., M.P.H.	Chief Medical Officer
Dr. Dylan Hartley Ph.D.	Chief Scientific Officer
Dr. Mark L. Boys Ph.D.	Senior Vice President of Discovery Chemistry
Ms. Roberta Alton	Senior Vice President of Clinical Operations

FAQs

What is OnKure Therapeutics share price today?

OnKure Therapeutics share price today is $3.94 as on August 22, 2026 at 8:46 am IST at the close of the market. OnKure Therapeutics share today touched a day high of $4.07 and a low of $3.90.

What is the 52 week high and 52 week low for OnKure Therapeutics share?

OnKure Therapeutics share touched a 52 week high of $5.38 on May 1, 2026 and a 52 week low of $2.23 on February 4, 2026. OnKure Therapeutics stock price today i.e. August 22, 2026 at 8:46 am IST is closed at $3.94,which is 26.77% down from its 52 week high and 76.68% up from its 52 week low.

What is OnKure Therapeutics's market capitalisation today?

OnKure Therapeutics market capitalisation is $0.00T as on August 22, 2026 at 8:46 am IST.

How to invest in OnKure Therapeutics Stock (OKUR) from India?

Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
Step 2: Search for OnKure Therapeutics on INDmoney app. Click on Buy button. You can invest as low as $1.5 in OnKure Therapeutics Shares that will get you 0.3807 shares as per OnKure Therapeutics share price of $3.94 per share as on August 22, 2026 at 8:46 am IST.

What is the minimum amount required to buy OnKure Therapeutics Stock (OKUR) from India?

Indian investors can start investing in OnKure Therapeutics (OKUR) shares with as little as ₹95.71 or $1 (as of August 24, 2026 at 4:42 am IST) using the INDmoney app.
For example: If you want to invest $10 or ₹957.10 in OnKure Therapeutics stock (as per the Rupee-Dollar exchange rate as on August 24, 2026 at 4:42 am IST). Based on OnKure Therapeutics share’s latest price of $3.94 as on August 22, 2026 at 8:46 am IST, you will get 2.5381 shares of OnKure Therapeutics. Learn more about fractional shares .