Denali Therapeutics Inc Stock Performance
as on December 9, 2025 at 1:39 am IST
Day's Low
Day's High
$19.75$20.57
0.45%
Downside
3.68%
Upside
52 Week's Low
52 Week's High
$10.57$26.1846.72%
Downside
31.96%
Upside
Denali Therapeutics Inc share price movements today
- Previous Close
- $19.96
- Open
- $20.23
- Volume
- 973.8K
- Day's Low - High
- $19.75 - $20.57
- 52 Week Low - High
- $10.57 - $26.18
Denali Therapeutics Inc Historical Returns
- 1 Month Return
- + 32.89 %
- 3 Month Return
- + 28.77 %
- 1 Year Return
- -19.81 %
- 3 Year Return
- -34.04 %
- 5 Year Return
- -74.07 %
Denali Therapeutics Inc Stock Fundamentals & Key Indicators
Check Denali Therapeutics Inc market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.
Market Cap
$2.9B
EPS (TTM)
-3.0133
Dividend Yield
0.00%
Quarterly Earnings Growth YOY
0.00%
PE Ratio (TTM)
-8.32
Industry PE ratio
8.214070796460177
PEG Ratio
0EBITDA
-542.1M
Revenue (TTM)
-
Profit Margin
0.00%
Return On Equity TTM
-44.44%
Denali Therapeutics Inc Stock Valuation
Track how Denali Therapeutics Inc P/E has moved over time to understand its valuation trends.
Denali Therapeutics Inc in the last 5 years
Lowest (-26.15x)
September 30, 2023
Today (-8.32x)
December 8, 2025
Industry (8.21x)
December 8, 2025
Highest (-5.03x)
June 30, 2025
Today’s Price to Earnings Ratio: -8.32x
Denali Therapeutics Inc vs Peer Comparison
Compare market cap, revenue, PE, and other key metrics of Denali Therapeutics Inc with its industry peers.
Company | Analyst View | Market Cap | 5 Years Return % | PE Ratio | Profit Margin % |
|---|---|---|---|---|---|
| BUY | $2.9B | -74.07% | -8.32 | 0.00% | |
| BUY | $43.5B | 418.42% | -16.34 | -264.83% | |
| BUY | $60.5B | 257.77% | 1431.62 | 1.36% | |
| BUY | $116.8B | 98.18% | 32.05 | 31.35% | |
| BUY | $76.1B | 44.5% | 17.21 | 32.13% |
Stock Returns calculator for Denali Therapeutics Inc Stock including INR - Dollar returns
The Denali Therapeutics Inc stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.
*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.
Investment Value
₹1,00,000
Denali Therapeutics Inc investment value today
Current value as on today
₹85,850
Returns
Returns from Denali Therapeutics Inc Stock
Dollar Returns*
₹6,139 (+6.14%)
Analyst Recommendation on Denali Therapeutics Inc Stock
Based on 23 analysts
86.96%
Buy
13.04%
Hold
0.00%
Sell
Based on 23 analysts, 86.96% of analysts recommend a 'BUY' rating for Denali Therapeutics Inc. Average target price of $32.29
Denali Therapeutics Inc Share Price Target
Get share price movements and forecasts by analysts on Denali Therapeutics Inc.
What analysts predicted
38.56%UPSIDE
Target Price
$32.29
Current Price
$19.84
Analyzed by
23 Analysts
Target
$32.29
Denali Therapeutics Inc target price $32.29, a slight upside of 38.56% compared to current price of $19.84. According to 23 analysts rating.
Denali Therapeutics Inc Stock’s Investor Sentiment and Interest
Search interest for Denali Therapeutics Inc Stock has decreased by -2% in the last 30 days, reflecting a downward trend in search activity.
Time period: to
Denali Therapeutics Inc Quarterly Profit & Loss
All numbers in Millions USD
Denali Therapeutics Inc Annual Profit & Loss
All numbers in Millions USD
Denali Therapeutics Inc Quarterly Cash Flow
All numbers in Millions USD
Denali Therapeutics Inc Annual Cash Flow
All numbers in Millions USD
Denali Therapeutics Inc News & Key Events
Today's Timeline - 14 October
Tue, 05:53 PM
-FDA extends review timeline for Denali's tividenofusp alfa from Jan. 5, 2026, to April 5, 2026, due to updated information submission.
Insights on Denali Therapeutics Inc
Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.
POSITIVE IMPACTPrice Rise
In the last 7 days, DNLI stock has moved up by 9.9%
NO EFFECTAgainst Peers
In the last 3 years, Insmed Incorporated has given 995.0% return, outperforming this stock by 1029.0%
- NO EFFECT
Against Peers
In the last 1 year, Insmed Incorporated has given 170.6% return, outperforming this stock by 190.4%
NEGATIVE IMPACTProfit Down
Netprofit is down for the last 2 quarters, -124.11M → -126.90M (in $), with an average decrease of 2.2% per quarter
- NEGATIVE IMPACT
Revenue Fall
Revenue is down for the last 3 quarters, 294.12M → -305.04M (in $), with an average decrease of 12137.8% per quarter
About Denali Therapeutics Inc
| Organisation | Denali Therapeutics Inc |
| Headquarters | 161 Oyster Point Boulevard, South San Francisco, CA, United States, 94080 |
| Industry | Health Technology |
| CEO | Dr. Ryan J. Watts Ph.D. |
| E-voting on shares | Click here to vote |
Key Management of Denali Therapeutics Inc
Name | Title |
|---|---|
Dr. Ryan J. Watts Ph.D. | Co-Founder, President, CEO & Director |
Dr. Alexander O. Schuth M.D. | Co-Founder, CFO, COO & Secretary |
Dr. Dana Andersen | Chief Technical and Manufacturing Officer |
Mr. Joe Lewcock Ph.D. | Chief Scientific Officer |
Mr. Chris Walsh J.D. | General Counsel |
Ms. Cindy Dunkle | Chief People Officer |
Ms. Katie Peng | Chief Commercial Officer |
Mr. Peter Chin M.D. | Acting Chief Medical Officer & Head of Development |
FAQs
What is Denali Therapeutics Inc share price today?
Denali Therapeutics Inc share price today is $19.84 as on . Denali Therapeutics Inc share today touched a day high of $20.57 and a low of $19.75.
What is the 52 week high and 52 week low for Denali Therapeutics Inc share?
Denali Therapeutics Inc share touched a 52 week high of $26.18 on and a 52 week low of $10.57 on . Denali Therapeutics Inc stock price today i.e. is trending at $19.84,which is 24.22% down from its 52 week high and 87.70% up from its 52 week low.
What is Denali Therapeutics Inc's market capitalisation today?
Denali Therapeutics Inc market capitalisation is $0.00T as on .
How to invest in Denali Therapeutics Inc Stock (DNLI) from India?
- Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
- Step 2: Search for Denali Therapeutics Inc on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Denali Therapeutics Inc Shares that will get you 0.0756 shares as per Denali Therapeutics Inc share price of $19.84 per share as on December 9, 2025 at 1:39 am IST.
What is the minimum amount required to buy Denali Therapeutics Inc Stock (DNLI) from India?
Indian investors can start investing in Denali Therapeutics Inc (DNLI) shares with as little as ₹90.066 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹900.66 in Denali Therapeutics Inc stock (as per the Rupee-Dollar exchange rate as on ).
Based on Denali Therapeutics Inc share’s latest price of $19.84 as on December 9, 2025 at 1:39 am IST, you will get 0.5040 shares of Denali Therapeutics Inc. Learn more about
fractional shares .
What are the returns that Denali Therapeutics Inc has given to Indian investors in the last 5 years?
Denali Therapeutics Inc stock has given -74.07% share price returns and 22% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?