Vyne Therapeutics Inc Share Price

NASDAQ: VYNE

Small Cap

$0.31

(+-0.31%)

as on September 17, 2025 at 1:29 am IST

$₹

Vyne Therapeutics Inc Stock Performance

as on September 17, 2025 at 1:29 am IST

Day's Low
Day's High
$0.3
Day's Price Range
$0.32
$0.31
3.23%
Downside
3.23%
Upside
52 Week's Low
52 Week's High
$0.28
52-Week Price Range
$4.3
$0.31
9.52%
Downside
1287.10%
Upside

Vyne Therapeutics Inc share price movements today

Previous Close: $0.31
Open: $0.31
Volume: 3.0M
Day's Low - High: $0.3 - $0.32
52 Week Low - High: $0.28 - $4.3

Vyne Therapeutics Inc Historical Returns

1 Month Return: -12.77 %
3 Month Return: -66.69 %
1 Year Return: -83.28 %
3 Year Return: -93.8 %
5 Year Return: -99.77 %

Vyne Therapeutics Inc Stock Fundamentals & Key Indicators

Check Vyne Therapeutics Inc market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$7.8M

EPS (TTM)

-0.89

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.00%

PE Ratio (TTM)

-0.94

Industry PE ratio

P/B Ratio

PEG Ratio

EBITDA

-43.6M

Revenue (TTM)

476.0K

Profit Margin

0.00%

Return On Equity TTM

32192100.00%

Vyne Therapeutics Inc Stock Valuation

Track how Vyne Therapeutics Inc P/E has moved over time to understand its valuation trends.

Vyne Therapeutics Inc in the last 5 years

Overview
Trends

Lowest (0.00x)

September 17, 2025

Industry (0.00x)

September 17, 2025

Today (-0.94x)

September 17, 2025

Highest (-0.35x)

March 31, 2023

LowHigh

Today’s Price to Earnings Ratio: -0.94x

Vyne Therapeutics Inc vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Vyne Therapeutics Inc with its industry peers.

Company	Analyst View	Market Cap	5 Years Return %	PE Ratio	Profit Margin %
Vyne Therapeutics Inc	BUY	$7.8M	-99.77%	-0.94	0.00%
Alnylam Pharmaceuticals, Inc.	BUY	$60.5B	252.04%	-505.15	-12.96%
Beone Medicines Ltd	NA	$39.0B	NA	NA	-3.89%
Vertex Pharmaceuticals Incorporated	BUY	$100.3B	44.17%	27.85	31.86%
Regeneron Pharmaceuticals, Inc.	BUY	$59.6B	1.78%	14.1	31.37%

Stock Returns calculator for Vyne Therapeutics Inc Stock including INR - Dollar returns

The Vyne Therapeutics Inc stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.

Investment Value

₹1,00,000

Vyne Therapeutics Inc investment value today

Current value as on today

₹21,807

Returns

₹78,193

(-78.19%)

Returns from Vyne Therapeutics Inc Stock

₹83,060 (-83.06%)

Dollar Returns*

₹4,867 (+4.87%)

Analyst Recommendation on Vyne Therapeutics Inc Stock

Based on 9 analysts

BUY

88.89%

Buy

11.11%

Hold

0.00%

Sell

Based on 9 analysts, 88.89% of analysts recommend a 'BUY' rating for Vyne Therapeutics Inc. Average target price of $4

Vyne Therapeutics Inc Share Price Target

Get share price movements and forecasts by analysts on Vyne Therapeutics Inc.

What analysts predicted

92.25%UPSIDE

Target Price

Current Price

$0.31

Analyzed by

9 Analysts

Target

$4.00

Vyne Therapeutics Inc target price $4, a slight upside of 92.25% compared to current price of $0.31. According to 9 analysts rating.

Vyne Therapeutics Inc Stock's Interest Amongst Investors

Search interest for Vyne Therapeutics Inc Stock has decreased by -14% in the last 30 days, reflecting a downward trend in search activity.

Time period: August 18, 2025 to September 17, 2025

Change:-14% versus previous 30 day period

Vyne Therapeutics Inc Quarterly Profit & Loss

All numbers in Millions USD

	Mar 2023	Jun 2023	Sep 2023	Dec 2023	Mar 2024	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025
Total Revenue	0	0	0	0	0	0	0	0	0	0
Gross Profit	0	0	0	0	0	0	0	0	0	0
Operating Income	-5	-10	-6	-6	-7	-10	-13	-12	-9	-7
EBITDA	-5	-10	-6	-6	-7	-9	-13	-12	-9	-7
Interest Expense	0	-	-	0	-	-	-	-	-	-
Depreciation	-	-	-	-	-	-	-	-	0	0
Income Before Tax	-5	-10	-6	-6	-6	-9	-12	-12	-8	-5
Income Tax Expense	0	0	0	0	0	0	-	0	0	-
Net Income	-5	-10	-6	-6	-6	-9	-12	-12	-8	-5
Net Profit Margin	-5678.79%	-7450.37%	-5775.44%	-8142.11%	-6376.53%	-4750.51%	-10047.11%	-14311.90%	-4262.87%	-8340.58%

Vyne Therapeutics Inc Annual Profit & Loss

All numbers in Millions USD

	Dec 2016	Dec 2017	Dec 2018	Dec 2019	Dec 2020	Dec 2021	Dec 2022	Dec 2023	Dec 2024
Total Revenue	0	4	10	1	20	14	0	0	0
Gross Profit	0	4	10	0	19	11	0	0	0
Operating Income	-14	-29	-54	-76	-113	-68	-34	-29	-43
EBITDA	-14	-29	-54	-75	-251	-38	-34	-29	-43
Interest Expense	-	0	3	2	4	5	10	-	-
Depreciation	-	0	0	0	0	0	0	0	0
Income Before Tax	-14	-29	-51	-73	-255	-73	-33	-27	-39
Income Tax Expense	0	0	3	-3	0	0	0	0	0
Net Income	-14	-29	-51	-70	-255	-73	-33	-28	-39
Net Profit Margin	-2087.24%	-634.57%	-483.51%	-4026.51%	-1217.40%	-496.98%	-7116.35%	-6710.38%	-7950.90%

Vyne Therapeutics Inc Quarterly Cash Flow

All numbers in Millions USD

	Jun 2023	Sep 2023	Dec 2023	Mar 2024	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025
Net Income	-10	-6	-6	-6	-9	-12	-12	-8	-5
Operating Cash Flow	-9	-5	-5	-7	-8	-8	-8	-11	-10
Investing Cash Flow	-	-	-62	-3	19	-4	12	19	4
Financing Cash Flow	0	0	82	0	0	0	0	0	0
Change in Cash	-9	-5	15	-11	10	-13	3	8	-6

Vyne Therapeutics Inc Annual Cash Flow

All numbers in Millions USD

	Dec 2016	Dec 2017	Dec 2018	Dec 2019	Dec 2020	Dec 2021	Dec 2022	Dec 2023	Dec 2024
Net Income	-14	-29	-51	-73	-255	-73	-23	-28	-39
Operating Cash Flow	-2	-28	-52	-65	-137	-56	-29	-25	-33
Investing Cash Flow	-37	-15	-33	41	89	1	15	-57	23
Financing Cash Flow	-	49	125	4	61	39	1	82	0
Change in Cash	-39	6	39	-18	13	-15	-11	0	-10

Global Institutional Holdings in Vyne Therapeutics Inc

Funds	Holdings
Eventide Asset Management, LLC	8.37%
Citadel Advisors Llc	6.6%
Dafna Capital Management LLC	3.82%
Vanguard Group Inc	2.85%
Exome Asset Management LLC	2.78%

See all

Insights on Vyne Therapeutics Inc

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

POSITIVE IMPACT
Profit Spike
Netprofit is up for the last 4 quarters, -12.15M → -5.75M (in $), with an average increase of 30.1% per quarter
NO EFFECT
Against Peers
In the last 1 year, Beone Medicines Ltd has given 68.2% return, outperforming this stock by 151.5%
NO EFFECT
Against Peers
In the last 3 years, Alnylam Pharmaceuticals, Inc. has given 111.5% return, outperforming this stock by 205.3%
NEGATIVE IMPACT
Price Dip
In the last 1 month, VYNE stock has moved down by -12.7%
NEGATIVE IMPACT
Revenue Fall
Revenue is down for the last 2 quarters, 202.0K → 69.0K (in $), with an average decrease of 65.8% per quarter

About Vyne Therapeutics Inc

vyne therapeutics inc., a pharmaceutical company, focuses on developing and commercializing various therapeutics for dermatology. it offers amzeeq, a topical minocycline used for the treatment of inflammatory lesions of non-nodular moderate-to-severe acne vulgaris in patients 9 years of age and older. the company is also developing fmx103, which is in phase iii clinical trials for the treatment of moderate-to-severe papulopustular rosacea in adults; and fcd105, a topical combination foam that is in phase ii clinical trials for the treatment of moderate-to-severe acne vulgaris. in addition, it is developing serlopitant, a once-daily oral nk1 receptor antagonist, used as a treatment option for pruritus associated with prurigo nodularis. the company was formerly known as menlo therapeutics inc. and changed its name to vyne therapeutics inc. in september 2020. vyne therapeutics inc. was founded in 2003 and is headquartered in bridgewater, new jersey.

Organisation	Vyne Therapeutics Inc
Headquarters	685 Route 202/206 N, Bridgewater, NJ, United States, 08807
Industry	Health Technology
CEO	Mr. David T. Domzalski
E-voting on shares	Click here to vote

Key Management of Vyne Therapeutics Inc

Name	Title
Mr. David T. Domzalski	CEO, President & Director
Dr. Iain A. Stuart Ph.D.	Chief Scientific Officer
Ms. Mutya Harsch J.D.	General Counsel, Chief Legal Officer & Company Secretary
Mr. Tyler Zeronda CPA	CFO & Treasurer
Dr. Darrell S. Rigel FAAD, M.D.	Consultant

FAQs

What is Vyne Therapeutics Inc share price today?

Vyne Therapeutics Inc share price today is $0.31 as on September 17, 2025 at 1:29 am IST at the close of the market. Vyne Therapeutics Inc share today touched a day high of $0.32 and a low of $0.3.

What is the 52 week high and 52 week low for Vyne Therapeutics Inc share?

Vyne Therapeutics Inc share touched a 52 week high of $4.3 on January 8, 2025 and a 52 week low of $0.28 on September 9, 2025. Vyne Therapeutics Inc stock price today i.e. September 17, 2025 at 1:29 am IST is closed at $0.31,which is 92.79% down from its 52 week high and 10.52% up from its 52 week low.

What is Vyne Therapeutics Inc's market capitalisation today?

Vyne Therapeutics Inc market capitalisation is $0.00T as on September 17, 2025 at 1:29 am IST.

How to invest in Vyne Therapeutics Inc Stock (VYNE) from India?

Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
Step 2: Search for Vyne Therapeutics Inc on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Vyne Therapeutics Inc Shares that will get you 4.8387 shares as per Vyne Therapeutics Inc share price of $0.31 per share as on September 17, 2025 at 1:29 am IST.

What is the minimum amount required to buy Vyne Therapeutics Inc Stock (VYNE) from India?

Indian investors can start investing in Vyne Therapeutics Inc (VYNE) shares with as little as ₹88.042 or $1 (as of September 17, 2025 at 2:41 pm IST) using the INDmoney app.
For example: If you want to invest $10 or ₹880.42 in Vyne Therapeutics Inc stock (as per the Rupee-Dollar exchange rate as on September 17, 2025 at 2:41 pm IST). Based on Vyne Therapeutics Inc share’s latest price of $0.31 as on September 17, 2025 at 1:29 am IST, you will get 32.2581 shares of Vyne Therapeutics Inc. Learn more about fractional shares .

What are the returns that Vyne Therapeutics Inc has given to Indian investors in the last 5 years?

Vyne Therapeutics Inc stock has given -99.77% share price returns and 20.01% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?