Sionna Therapeutics Share Price

NASDAQ: SION

Large Cap

$22.20

-1.07

(-4.60%)

as on September 18, 2025 at 1:29 am IST

$₹

Sionna Therapeutics Stock Performance

as on September 18, 2025 at 1:29 am IST

Day's Low
Day's High
$22
Day's Price Range
$24.77
$22.2
0.90%
Downside
11.58%
Upside
52 Week's Low
52 Week's High
$7.26
52-Week Price Range
$26.5
$22.2
67.32%
Downside
19.37%
Upside

Sionna Therapeutics share price movements today

Previous Close: $23.27
Open: $23.99
Volume: 166.3K
Day's Low - High: $22 - $24.77
52 Week Low - High: $7.26 - $26.5

Sionna Therapeutics Historical Returns

1 Month Return: + 8.79 %
3 Month Return: + 57.98 %
1 Year Return: 0 %
3 Year Return: 0 %
5 Year Return: 0 %

Sionna Therapeutics Stock Fundamentals & Key Indicators

Check Sionna Therapeutics market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$769.0M

EPS (TTM)

-2.34

Dividend Yield

0.00%

PE Ratio (TTM)

P/B Ratio

PEG Ratio

Return On Equity TTM

106518700.00%

Sionna Therapeutics vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Sionna Therapeutics with its industry peers.

Company	Analyst View	Market Cap	5 Years Return %	PE Ratio	Profit Margin %
Sionna Therapeutics	NA	$769.0M	NA	NA	0.00%
Alnylam Pharmaceuticals, Inc.	BUY	$60.5B	252.04%	-505.15	-12.96%
Beone Medicines Ltd	NA	$39.0B	NA	NA	-3.89%
Vertex Pharmaceuticals Incorporated	BUY	$100.3B	44.17%	27.85	31.86%
Regeneron Pharmaceuticals, Inc.	BUY	$59.6B	1.78%	14.1	31.37%

Sionna Therapeutics Stock's Interest Amongst Investors

Search interest for Sionna Therapeutics Stock has decreased by -20% in the last 30 days, reflecting a downward trend in search activity.

Time period: August 19, 2025 to September 18, 2025

Change:-20% versus previous 30 day period

Sionna Therapeutics Quarterly Profit & Loss

All numbers in Millions USD

	Dec 2023	Mar 2024	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025
Total Revenue	-	-	-	-	-	-	-
Gross Profit	-	-	0	-	-	-	0
Operating Income	-12	-13	-11	-27	-18	-19	-21
EBITDA	-12	-12	-8	-	-17	-19	-21
Interest Expense	-	-	-	-	-	-	-
Depreciation	0	0	0	0	0	0	0
Income Before Tax	-11	-11	-8	-25	-15	-16	-18
Income Tax Expense	-	-	-	-	-	-	-
Net Income	-11	-11	-8	-25	-15	-16	-18
Net Profit Margin	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Sionna Therapeutics Annual Profit & Loss

All numbers in Millions USD

	Dec 2022	Dec 2023	Dec 2024
Total Revenue	-	-	-
Gross Profit	-	-	-
Operating Income	-41	-50	-70
EBITDA	-41	-49	-69
Interest Expense	-	-	-
Depreciation	0	0	0
Income Before Tax	-40	-47	-61
Income Tax Expense	-	-	-
Net Income	-40	-47	-61
Net Profit Margin	0.00%	0.00%	0.00%

Sionna Therapeutics Quarterly Cash Flow

All numbers in Millions USD

	Mar 2024	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025
Net Income	-11	-8	-25	-15	-16	-18
Operating Cash Flow	-13	-10	-17	-11	-16	-18
Investing Cash Flow	-123	-28	-	15	-141	-23
Financing Cash Flow	181	0	0	-1	202	0
Change in Cash	44	-38	-8	2	44	-41

Sionna Therapeutics Annual Cash Flow

All numbers in Millions USD

	Dec 2023	Dec 2024
Net Income	-47	-61
Operating Cash Flow	-43	-52
Investing Cash Flow	27	-126
Financing Cash Flow	0	178
Change in Cash	-16	0

Insights on Sionna Therapeutics

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

NEGATIVE IMPACT
Price Dip
In the last 7 days, SION stock has moved down by -6.6%

About Sionna Therapeutics

Sionna Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on researching and developing novel medicines for cystic fibrosis. It is advancing a pipeline of small molecules engineered to correct the defects caused by the F508del genetic mutation, which resides in nucleotide-binding domain 1 (NBD1). It is conducting ongoing Phase I trials of its two highly potent NBD1 stabilizers, SION-719 and SION-451, evaluating the safety, tolerability and pharmacokinetic (PK) profile of single and multiple ascending doses in healthy subjects. It is also developing a portfolio of cystic fibrosis transmembrane conductance regulator (CFTR) modulators designed to work synergistically with its NBD1 stabilizers to improve CFTR function. Its portfolio also includes Galicaftor (SION-2222) and SION-2851, which are TMD1-directed CFTR correctors; SION-109, an ICL4-directed CFTR corrector, and Navocaftor (SION-3067), is a clinical-stage potentiator of CFTR gating activity.

Organisation	Sionna Therapeutics
Headquarters	21 Hickory Drive, Waltham, MA, United States, 02451
CEO	Mr. Michael Cloonan M.B.A.
E-voting on shares	Click here to vote

Key Management of Sionna Therapeutics

Name	Title
Mr. Michael Cloonan M.B.A.	President, CEO & Director
Dr. Mark Munson Ph.D.	Co-founder & Senior VP of Medicinal Chemistry
Mr. Andy Chu	Vice President of Information & Technology
Ms. Jennifer Fitzpatrick J.D.	Chief Legal Officer
Ms. Vanya Sagar	Chief People Officer
Ms. Elena H. Ridloff C.F.A.	CFO & Head of Corporate Development
Dr. Charlotte McKee M.D.	Chief Medical Officer
Dr. Greg Hurlbut Ph.D.	Co-Founder & Senior VP of Discovery Research
Ms. Meghan Bagshaw	Vice President of Programs, Portfolio & Operations
Ms. Mara Furlow M.S.	Senior Vice President of Global Regulatory Affairs & Quality

FAQs

What is Sionna Therapeutics share price today?

Sionna Therapeutics share price today is $22.2 as on September 18, 2025 at 1:29 am IST at the close of the market. Sionna Therapeutics share today touched a day high of $24.77 and a low of $22.

What is the 52 week high and 52 week low for Sionna Therapeutics share?

Sionna Therapeutics share touched a 52 week high of $26.5 on August 28, 2025 and a 52 week low of $7.26 on April 11, 2025. Sionna Therapeutics stock price today i.e. September 18, 2025 at 1:29 am IST is closed at $22.2,which is 16.23% down from its 52 week high and 206.00% up from its 52 week low.

What is Sionna Therapeutics's market capitalisation today?

Sionna Therapeutics market capitalisation is $0.00T as on September 18, 2025 at 1:29 am IST.

How to invest in Sionna Therapeutics Stock (SION) from India?

Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
Step 2: Search for Sionna Therapeutics on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Sionna Therapeutics Shares that will get you 0.0676 shares as per Sionna Therapeutics share price of $22.2 per share as on September 18, 2025 at 1:29 am IST.

What is the minimum amount required to buy Sionna Therapeutics Stock (SION) from India?

Indian investors can start investing in Sionna Therapeutics (SION) shares with as little as ₹87.816 or $1 (as of September 18, 2025 at 12:41 pm IST) using the INDmoney app.
For example: If you want to invest $10 or ₹878.16 in Sionna Therapeutics stock (as per the Rupee-Dollar exchange rate as on September 18, 2025 at 12:41 pm IST). Based on Sionna Therapeutics share’s latest price of $22.2 as on September 18, 2025 at 1:29 am IST, you will get 0.4505 shares of Sionna Therapeutics. Learn more about fractional shares .