Sionna Therapeutics share price logo

Sionna Therapeutics Share Price

NASDAQ: SION

Small Cap

$40.41

-0.48

(-1.16%)

as on

Sionna Therapeutics Stock Performance

as on December 6, 2025 at 2:29 am IST

  • Day's Low

    Day's High

    $39.75
    $42.02
    downward going graph

    1.63%

    Downside

    3.98%

    Upside

    downward going graph

  • 52 Week's Low

    52 Week's High

    $7.26
    $45
    downward going graph

    82.05%

    Downside

    11.36%

    Upside

    downward going graph

Sionna Therapeutics share price movements today

Previous Close
$40.88
Open
$41.05
Volume
513.1K
Day's Low - High
$39.75 - $42.02
52 Week Low - High
$7.26 - $45

Sionna Therapeutics Historical Returns

1 Month Return
+ 17.12 %
3 Month Return
+ 67.88 %
1 Year Return
0 %
3 Year Return
0 %
5 Year Return
0 %

Sionna Therapeutics Stock Fundamentals & Key Indicators

Check Sionna Therapeutics market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$1.8B

EPS (TTM)

-2.0314

Dividend Yield

0.00%

PE Ratio (TTM)

0

PEG Ratio

0

Return On Equity TTM

-28.08%

Sionna Therapeutics vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Sionna Therapeutics with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %
Sionna Therapeutics image
Sionna Therapeutics
NA$1.8BNANA0.00%
Insmed Incorporated image
Insmed Incorporated
BUY$43.5B408.22%-16.34-264.83%
Alnylam Pharmaceuticals, Inc. image
Alnylam Pharmaceuticals, Inc.
BUY$61.5B253.6%1661.931.36%
Vertex Pharmaceuticals Incorporated image
Vertex Pharmaceuticals Incorporated
BUY$117.3B99.49%32.1631.35%
Regeneron Pharmaceuticals, Inc. image
Regeneron Pharmaceuticals, Inc.
BUY$76.6B45.87%17.3132.13%

Sionna Therapeutics Stock’s Investor Sentiment and Interest

Search interest for Sionna Therapeutics Stock has increased by 33% in the last 30 days, reflecting an upward trend in search activity.

Time period: to

Change:33% versus previous 30 day period

Sionna Therapeutics Quarterly Profit & Loss

All numbers in Millions USD

Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Total Revenue
-
-
-
-
-
-
-
-
Gross Profit
-
-
0
-
-
-
0
0
Operating Income
-12
-13
-11
-27
-18
-19
-21
-23
EBITDA
-12
-12
-8
-27
-17
-19
-17
-20
Interest Expense
-
-
-
-
-
-
-
-
Depreciation
0
0
0
0
0
0
0
0
Income Before Tax
-11
-11
-8
-25
-15
-16
-18
-20
Income Tax Expense
-
-
-
-
-
-
-
-
Net Income
-11
-11
-8
-25
-15
-16
-18
-20
Net Profit Margin
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%

Sionna Therapeutics Annual Profit & Loss

All numbers in Millions USD

Dec 2022
Dec 2023
Dec 2024
Total Revenue
-
-
-
Gross Profit
-
-
0
Operating Income
-41
-50
-70
EBITDA
-41
-49
-69
Interest Expense
-
-
-
Depreciation
0
0
0
Income Before Tax
-40
-47
-61
Income Tax Expense
-
-
-
Net Income
-40
-47
-61
Net Profit Margin
0.00%
0.00%
0.00%

Sionna Therapeutics Quarterly Cash Flow

All numbers in Millions USD

Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Net Income
-11
-8
-25
-15
-16
-18
-20
Operating Cash Flow
-13
-10
-17
-11
-16
-18
-15
Investing Cash Flow
-123
-28
10
15
-141
-23
23
Financing Cash Flow
181
0
0
-1
202
0
1
Change in Cash
44
-38
-8
2
44
-41
9

Sionna Therapeutics Annual Cash Flow

All numbers in Millions USD

Dec 2023
Dec 2024
Net Income
-47
-61
Operating Cash Flow
-43
-52
Investing Cash Flow
27
-126
Financing Cash Flow
0
178
Change in Cash
-16
0

Insights on Sionna Therapeutics

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Price Rise

    img

    In the last 1 month, SION stock has moved up by 19.8%

About Sionna Therapeutics

Sionna Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on researching and developing novel medicines for cystic fibrosis. It is advancing a pipeline of small molecules engineered to correct the defects caused by the F508del genetic mutation, which resides in nucleotide-binding domain 1 (NBD1). It is conducting ongoing Phase I trials of its two highly potent NBD1 stabilizers, SION-719 and SION-451, evaluating the safety, tolerability and pharmacokinetic (PK) profile of single and multiple ascending doses in healthy subjects. It is also developing a portfolio of cystic fibrosis transmembrane conductance regulator (CFTR) modulators designed to work synergistically with its NBD1 stabilizers to improve CFTR function. Its portfolio also includes Galicaftor (SION-2222) and SION-2851, which are TMD1-directed CFTR correctors; SION-109, an ICL4-directed CFTR corrector, and Navocaftor (SION-3067), is a clinical-stage potentiator of CFTR gating activity.
OrganisationSionna Therapeutics
Headquarters21 Hickory Drive, Waltham, MA, United States, 02451
CEOMr. Michael Cloonan M.B.A.
E-voting on sharesClick here to vote

Key Management of Sionna Therapeutics

Name

Title

Mr. Michael Cloonan M.B.A.

President, CEO & Director

Ms. Elena H. Ridloff C.F.A.

Chief Financial Officer

Dr. Charlotte McKee M.D.

Chief Medical Officer

Dr. Mark Munson Ph.D.

Co-founder & Senior VP of Medicinal Chemistry

Ms. Mara Furlow M.S.

Senior Vice President of Global Regulatory Affairs & Quality

Dr. Greg Hurlbut Ph.D.

Co-Founder & Senior VP of Discovery Research

Ms. Meghan Bagshaw

Vice President of Programs, Portfolio & Operations

Mr. Andy Chu

Vice President of Information & Technology

Ms. Jennifer Fitzpatrick J.D.

Chief Legal Officer

Ms. Vanya Sagar

Chief People Officer

FAQs

What is Sionna Therapeutics share price today?

Sionna Therapeutics share price today is $40.41 as on at the close of the market. Sionna Therapeutics share today touched a day high of $42.02 and a low of $39.75.

What is the 52 week high and 52 week low for Sionna Therapeutics share?

Sionna Therapeutics share touched a 52 week high of $45 on and a 52 week low of $7.26 on . Sionna Therapeutics stock price today i.e. is closed at $40.41,which is 10.20% down from its 52 week high and 457.00% up from its 52 week low.

What is Sionna Therapeutics's market capitalisation today?

Sionna Therapeutics market capitalisation is $0.00T as on .

How to invest in Sionna Therapeutics Stock (SION) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Sionna Therapeutics on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Sionna Therapeutics Shares that will get you 0.0371 shares as per Sionna Therapeutics share price of $40.41 per share as on December 6, 2025 at 2:29 am IST.

What is the minimum amount required to buy Sionna Therapeutics Stock (SION) from India?

Indian investors can start investing in Sionna Therapeutics (SION) shares with as little as ₹89.927 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹899.27 in Sionna Therapeutics stock (as per the Rupee-Dollar exchange rate as on ). Based on Sionna Therapeutics share’s latest price of $40.41 as on December 6, 2025 at 2:29 am IST, you will get 0.2475 shares of Sionna Therapeutics. Learn more about fractional shares .