Sionna Therapeutics share price logo

Sionna Therapeutics Share Price

NASDAQ: SION

Small Cap

$40.70

+0.70

(+1.74%)

Live

as on

Sionna Therapeutics Stock Performance

as on January 21, 2026 at 8:41 pm IST

  • Day's Low

    $39.11
    $40.70
    downward going graph

    3.91%

    Downside

  • 52 Week's Low

    52 Week's High

    $7.26
    $45.00
    downward going graph

    82.17%

    Downside

    10.57%

    Upside

    downward going graph

Sionna Therapeutics share price movements today

Previous Close
$40.01
Open
$39.11
Volume
10.3K
Day's Low - High
$39.11 - $40.70
52 Week Low - High
$7.26 - $45.00

Sionna Therapeutics Historical Returns

1 Month Return
-5.57 %
3 Month Return
-5.86 %
1 Year Return
0 %
3 Year Return
0 %
5 Year Return
0 %

Sionna Therapeutics Stock Fundamentals & Key Indicators

Check Sionna Therapeutics market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$1.7B

EPS (TTM)

-1.995

Dividend Yield

0.00%

PE Ratio (TTM)

0

PEG Ratio

0

Return On Equity TTM

-28.08%

Sionna Therapeutics vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Sionna Therapeutics with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %
Sionna Therapeutics image
Sionna Therapeutics
NA$1.7BNANA0.00%
Alnylam Pharmaceuticals, Inc. image
Alnylam Pharmaceuticals, Inc.
BUY$47.4B113.21%1237.911.36%
Vertex Pharmaceuticals Incorporated image
Vertex Pharmaceuticals Incorporated
BUY$113.2B85.25%31.0631.35%
Beone Medicines Ltd image
Beone Medicines Ltd
NA$37.4BNA663.121.38%
Regeneron Pharmaceuticals, Inc. image
Regeneron Pharmaceuticals, Inc.
BUY$77.7B37.03%17.5732.13%

Sionna Therapeutics Stock’s Investor Sentiment and Interest

Search interest for Sionna Therapeutics Stock has increased by 242% in the last 30 days, reflecting an upward trend in search activity.

Time period: to

Change:242% versus previous 30 day period

Sionna Therapeutics Quarterly Profit & Loss

All numbers in Millions USD

Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Total Revenue
-
-
-
-
-
-
-
-
Gross Profit
-
-
0
-
-
-
0
0
Operating Income
-12
-13
-11
-27
-18
-19
-21
-23
EBITDA
-12
-12
-8
-27
-17
-19
-17
-20
Interest Expense
-
-
-
-
-
-
-
-
Depreciation
0
0
0
0
0
0
0
0
Income Before Tax
-11
-11
-8
-25
-15
-16
-18
-20
Income Tax Expense
-
-
-
-
-
-
-
-
Net Income
-11
-11
-8
-25
-15
-16
-18
-20
Net Profit Margin
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%

Sionna Therapeutics Annual Profit & Loss

All numbers in Millions USD

Dec 2022
Dec 2023
Dec 2024
Total Revenue
-
-
-
Gross Profit
-
-
0
Operating Income
-41
-50
-70
EBITDA
-41
-49
-69
Interest Expense
-
-
-
Depreciation
0
0
0
Income Before Tax
-40
-47
-61
Income Tax Expense
-
-
-
Net Income
-40
-47
-61
Net Profit Margin
0.00%
0.00%
0.00%

Sionna Therapeutics Quarterly Cash Flow

All numbers in Millions USD

Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Net Income
-11
-8
-25
-15
-16
-18
-20
Operating Cash Flow
-13
-10
-17
-11
-16
-18
-15
Investing Cash Flow
-123
-28
10
15
-141
-23
23
Financing Cash Flow
181
0
0
-1
202
0
1
Change in Cash
44
-38
-8
2
44
-41
9

Sionna Therapeutics Annual Cash Flow

All numbers in Millions USD

Dec 2023
Dec 2024
Net Income
-47
-61
Operating Cash Flow
-43
-52
Investing Cash Flow
27
-126
Financing Cash Flow
0
178
Change in Cash
-16
0

Insights on Sionna Therapeutics

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Price Rise

    img

    In the last 6 months, SION stock has moved up by 129.4%

About Sionna Therapeutics

Sionna Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on researching and developing novel medicines for cystic fibrosis. It is advancing a pipeline of small molecules engineered to correct the defects caused by the F508del genetic mutation, which resides in nucleotide-binding domain 1 (NBD1). It is conducting ongoing Phase I trials of its two highly potent NBD1 stabilizers, SION-719 and SION-451, evaluating the safety, tolerability and pharmacokinetic (PK) profile of single and multiple ascending doses in healthy subjects. It is also developing a portfolio of cystic fibrosis transmembrane conductance regulator (CFTR) modulators designed to work synergistically with its NBD1 stabilizers to improve CFTR function. Its portfolio also includes Galicaftor (SION-2222) and SION-2851, which are TMD1-directed CFTR correctors; SION-109, an ICL4-directed CFTR corrector, and Navocaftor (SION-3067), is a clinical-stage potentiator of CFTR gating activity.
OrganisationSionna Therapeutics
Headquarters21 Hickory Drive, Waltham, MA, United States, 02451
CEOMr. Michael Cloonan M.B.A.
E-voting on sharesClick here to vote

Key Management of Sionna Therapeutics

Name

Title

Dr. Mark Munson Ph.D.

Co-founder & Senior VP of Medicinal Chemistry

Mr. Andy Chu

Vice President of Information & Technology

Ms. Jennifer Fitzpatrick J.D.

Chief Legal Officer

Ms. Vanya Sagar

Chief People Officer

Ms. Elena H. Ridloff C.F.A.

Chief Financial Officer

Dr. Charlotte McKee M.D.

Chief Medical Officer

Dr. Greg Hurlbut Ph.D.

Co-Founder & Senior VP of Discovery Research

Ms. Meghan Bagshaw

Vice President of Programs, Portfolio & Operations

Ms. Mara Furlow M.S.

Senior Vice President of Global Regulatory Affairs & Quality

Mr. Michael Cloonan M.B.A.

President, CEO & Director

FAQs

What is Sionna Therapeutics share price today?

Sionna Therapeutics share price today is $40.7 as on . Sionna Therapeutics share today touched a day high of $40.7 and a low of $39.11.

What is the 52 week high and 52 week low for Sionna Therapeutics share?

Sionna Therapeutics share touched a 52 week high of $45 on and a 52 week low of $7.26 on . Sionna Therapeutics stock price today i.e. is trending at $40.7,which is 9.56% down from its 52 week high and 460.99% up from its 52 week low.

What is Sionna Therapeutics's market capitalisation today?

Sionna Therapeutics market capitalisation is $0.00T as on .

How to invest in Sionna Therapeutics Stock (SION) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Sionna Therapeutics on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Sionna Therapeutics Shares that will get you 0.0369 shares as per Sionna Therapeutics share price of $40.7 per share as on January 21, 2026 at 8:41 pm IST.

What is the minimum amount required to buy Sionna Therapeutics Stock (SION) from India?

Indian investors can start investing in Sionna Therapeutics (SION) shares with as little as ₹91.673 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹916.73 in Sionna Therapeutics stock (as per the Rupee-Dollar exchange rate as on ). Based on Sionna Therapeutics share’s latest price of $40.7 as on January 21, 2026 at 8:41 pm IST, you will get 0.2457 shares of Sionna Therapeutics. Learn more about fractional shares .