Spruce Biosciences
NASDAQ: SPRB
$53.20
Live
as on
Spruce Biosciences Stock Performance
as on September 19, 2026 at 5:04 am IST
Day's Low
Day's High
$51.80$53.49
2.63%
Downside
0.55%
Upside
52 Week's Low
52 Week's High
$7.26$240.0086.35%
Downside
351.13%
Upside
Spruce Biosciences share price movements today
- Previous Close
- $53.86
- Open
- $52.11
- Volume
- 112.9K
- Market Cap
- $154.8M
- Day's Low - High
- $51.80 - $53.49
- 52 Week Low - High
- $7.26 - $240.00
Spruce Biosciences Historical Returns
- 1 Month Return
- + 1.92 %
- 3 Month Return
- + 2.86 %
- 1 Year Return
- + 506.36 %
- 3 Year Return
- -70.33 %
- 5 Year Return
- -89.89 %
Spruce Biosciences Stock Fundamentals & Key Indicators
Check Spruce Biosciences market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.
Market Cap
$154.8M
EPS (TTM)
-40.87
Dividend Yield
0.00%
Quarterly Earnings Growth YOY
0.00%
PE Ratio (TTM)
-1.32
Industry PE ratio
-2.37
PEG Ratio
-0.019944927300410174
EBITDA
-48.7M
Revenue (TTM)
-
Profit Margin
0.00%
Return On Equity TTM
-123.53%
Spruce Biosciences Stock Valuation
Track how Spruce Biosciences P/E has moved over time to understand its valuation trends.
Spruce Biosciences in the last 5 years
Lowest (-4.80x)
December 31, 2021
Industry (-2.37x)
December 31, 2025
Today (-1.71x)
December 31, 2025
Highest (-0.33x)
December 31, 2024
Today’s Price to Earnings Ratio: -1.71x
Spruce Biosciences vs Peer Comparison
Compare market cap, revenue, PE, and other key metrics of Spruce Biosciences with its industry peers.
Company | Analyst View | Market Cap | 5 Years Return % | PE Ratio | Profit Margin % | Dividend Yield % |
|---|---|---|---|---|---|---|
| BUY | $154.8M | -89.89% | -1.32 | 0.00% | 0.00% | |
| BUY | $42.2B | 530.61% | -22.23 | 0.00% | 0.00% | |
| BUY | $130.1B | 174.21% | 29.81 | 86.04% | 0.00% | |
| BUY | $63.1B | -63.24% | -19.81 | -12.57% | 0.00% | |
| BUY | $79.7B | 21.1% | 18.48 | 84.86% | 0.48% |
Stock Returns calculator for Spruce Biosciences Stock including INR - Dollar returns
The Spruce Biosciences stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.
*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.
Investment Value
₹1,00,000
Spruce Biosciences investment value today
Current value as on today
₹6,54,407
Returns
₹5,54,407
(+554.41%)
Returns from Spruce Biosciences Stock
₹4,98,930 (+498.93%)
Dollar Impact
₹55,477 (+55.48%)
Analyst Recommendation on Spruce Biosciences Stock
Based on 6 analysts
100.00%
Buy
0.00%
Hold
0.00%
Sell
Based on 6 analysts, 100% of analysts recommend a 'BUY' rating for Spruce Biosciences. Average target price of $147.88
Spruce Biosciences Share Price Target
Get share price movements and forecasts by analysts on Spruce Biosciences.
What analysts predicted
64.02%UPSIDE
Target Price
$147.88
Current Price
$53.2
Analyzed by
6 Analysts
Target
$147.88
Spruce Biosciences target price $147.88, a slight upside of 64.02% compared to current price of $53.2. According to 6 analysts rating.
Indian Investors' Interest in Spruce Biosciences Stock
Search interest for Spruce Biosciences Stock has increased by 41% in the last 30 days, reflecting an upward trend in search activity.
Time period: to
Change:41% versus previous 30 day period
Spruce Biosciences Quarterly Profit & Loss
All numbers in Millions USD
Spruce Biosciences Annual Profit & Loss
All numbers in Millions USD
Spruce Biosciences Quarterly Cash Flow
All numbers in Millions USD
Spruce Biosciences Annual Cash Flow
All numbers in Millions USD
Spruce Biosciences News & Key Events
Today's Timeline - 08 October
Thu, 02:02 AM
-Spruce Biosciences announces $50M private placement to advance enzyme replacement therapy for Sanfilippo Syndrome Type B.
Insights on Spruce Biosciences
Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.
POSITIVE IMPACTPrice Rise
In the last 1 year, SPRB stock has moved up by 506.4%
NO EFFECTAgainst Peers
In the last 1 year, Moderna, Inc. Common Stock has given 521.1% return, outperforming this stock by 14.7%
- NO EFFECT
Against Peers
In the last 3 years, Moderna, Inc. Common Stock has given 51.8% return, outperforming this stock by 122.1%
About Spruce Biosciences
| Organisation | Spruce Biosciences |
| Headquarters | 611 Gateway Boulevard, South San Francisco, CA, United States, 94080 |
| Industry | Biotechnology |
| CEO | Dr. Javier Szwarcberg M.D., M.P.H. |
| E-voting on shares | Click here to vote |
Key Management of Spruce Biosciences
Name | Title |
|---|---|
Dr. Kirk Ways M.D., Ph.D. | Director |
Mr. Eric Jordan M.B.A. | Vice President of Marketing |
Mr. Corwin Dale Hooks M.B.A. | Chief Commercial Officer |
Ms. Saba Sile M.D. | Senior Vice President of Clinical Development |
Dr. Adrian Quartel FFPM, M.D. | Chief Medical Officer |
Mr. Michael G. Grey | Executive Chairman |
Dr. Javier Szwarcberg M.D., M.P.H. | CEO & Director |
Mr. Samir M. Gharib CPA, M.B.A. | President & CFO |
Mr. Bruno Gagnon BPHARM, M.Sc. | Senior Vice President of Clinical Development Operations |
Dr. Daven Mody M.B.A., Pharm.D. | Senior Vice President of Regulatory & Quality |
FAQs
What is Spruce Biosciences share price today?
Spruce Biosciences share price today is $53.20 as on . Spruce Biosciences share today touched a day high of $53.49 and a low of $51.80.
What is the 52 week high and 52 week low for Spruce Biosciences share?
Spruce Biosciences share touched a 52 week high of $240.00 on and a 52 week low of $7.26 on . Spruce Biosciences stock price today i.e. is trending at $53.20,which is 77.83% down from its 52 week high and 632.78% up from its 52 week low.
What is Spruce Biosciences's market capitalisation today?
Spruce Biosciences market capitalisation is $0.00T as on .
How to invest in Spruce Biosciences Stock (SPRB) from India?
- Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
- Step 2: Search for Spruce Biosciences on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Spruce Biosciences Shares that will get you 0.0282 shares as per Spruce Biosciences share price of $53.20 per share as on September 18, 2026 at 11:34 pm IST.
What is the minimum amount required to buy Spruce Biosciences Stock (SPRB) from India?
Indian investors can start investing in Spruce Biosciences (SPRB) shares with as little as ₹95.8725 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹958.73 in Spruce Biosciences stock (as per the Rupee-Dollar exchange rate as on ).
Based on Spruce Biosciences share’s latest price of $53.20 as on September 18, 2026 at 11:34 pm IST, you will get 0.1880 shares of Spruce Biosciences. Learn more about
fractional shares .
What are the returns that Spruce Biosciences has given to Indian investors in the last 5 years?
Spruce Biosciences stock has given -89.89% share price returns and 29.78% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?