Spruce Biosciences Inc Share Price

NASDAQ: SPRB

$10.12

+10.04

(+12107.48%)

as on September 16, 2025 at 1:28 am IST

$₹

The stock has been delisted from the stock exchange

Spruce Biosciences Inc Stock Performance

as on September 16, 2025 at 1:28 am IST

Day's Low
Day's High
$0.08
Day's Price Range
$0.08
$10.12
99.21%
Downside
-99.21%
Upside
52 Week's Low
52 Week's High
$0.08
52-Week Price Range
$0.61
$10.12
99.23%
Downside
-93.99%
Upside

Spruce Biosciences Inc share price movements today

Previous Close: $0.08
Open: $0.08
Volume: 6.9K
Day's Low - High: $0.08 - $0.08
52 Week Low - High: $0.08 - $0.61

Spruce Biosciences Inc Historical Returns

1 Month Return: 0 %
3 Month Return: 0 %
1 Year Return: 0 %
3 Year Return: 0 %
5 Year Return: 0 %

Spruce Biosciences Inc Stock Fundamentals & Key Indicators

Check Spruce Biosciences Inc market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

EPS (TTM)

Dividend Yield

0.00%

PE Ratio (TTM)

P/B Ratio

PEG Ratio

Return On Equity TTM

0.00%

Spruce Biosciences Inc stock Key Stats

Compare market cap, revenue, PE, and other key metrics of Spruce Biosciences Inc with its industry peers.

Company	Analyst View	Market Cap	5 Years Return %	PE Ratio	Profit Margin %
Spruce Biosciences Inc	BUY	$-	NA	NA	0.00%

Analyst Recommendation on Spruce Biosciences Inc Stock

Based on 13 analysts

BUY

53.85%

Buy

46.15%

Hold

0.00%

Sell

Based on 13 analysts, 53.85% of analysts recommend a 'BUY' rating for Spruce Biosciences Inc. Average target price of $0.75

Spruce Biosciences Inc Share Price Target

Get share price movements and forecasts by analysts on Spruce Biosciences Inc.

What analysts predicted

-1249.33%DOWNSIDE

Target Price

$0.75

Current Price

$10.12

Analyzed by

13 Analysts

Target

$0.75

Spruce Biosciences Inc target price $0.75, a slight downside of -1249.33% compared to current price of $10.12. According to 13 analysts rating.

Spruce Biosciences Inc Quarterly Profit & Loss

All numbers in Millions USD

	Dec 2022	Mar 2023	Jun 2023	Sep 2023	Dec 2023	Mar 2024	Jun 2024	Sep 2024	Dec 2024	Mar 2025
Total Revenue	-	1	2	3	2	2	1	0	0	0
Gross Profit	0	1	2	3	2	1	-6	0	-	0
Operating Income	-	-	-	-	-	-	-	-	-	-
EBITDA	-	-	-	-	-	-	-	-	-	-
Interest Expense	-	-	-	-	-	-	-	-	-	-
Depreciation	-	-	-	-	-	-	-	-	-	-
Income Before Tax	-	-	-	-	-	-	-	-	-	-
Income Tax Expense	-	-	-	-	-	-	-	-	-	-
Net Income	-10	-12	-12	-12	-9	-11	-9	-8	-23	-23
Net Profit Margin	0.00%	-637.17%	-592.33%	-402.02%	-344.65%	-580.67%	-570.25%	-1440.37%	-3380.06%	-3380.06%

Spruce Biosciences Inc Annual Profit & Loss

All numbers in Millions USD

	Dec 2018	Dec 2019	Dec 2020	Dec 2021	Dec 2022	Dec 2023	Dec 2024
Total Revenue	-	-	-	-	1	10	4
Gross Profit	0	0	0	0	0	-39	4
Operating Income	-	-	-	-	-	-	-
EBITDA	-	-	-	-	-	-	-
Interest Expense	-	-	-	-	-	-	-
Depreciation	-	-	-	-	-	-	-
Income Before Tax	-	-	-	-	-	-	-
Income Tax Expense	-	-	-	-	-	-	-
Net Income	-9	-13	-30	-42	-45	-47	-53
Net Profit Margin	0.00%	0.00%	0.00%	0.00%	-2295.16%	-474.96%	-1079.94%

Global Institutional Holdings in Spruce Biosciences Inc

Funds	Holdings
RiverVest Venture Management LLC	6.96%
The Carlyle Group Inc	6.86%
Rock Springs Capital Management LP	6.18%
Ikarian Capital, LLC	2.37%
Vanguard Group Inc	2%

See all

About Spruce Biosciences Inc

Spruce Biosciences, Inc. is a late-stage biopharmaceutical company focused on developing and commercializing therapies for neurological disorders with significant unmet medical need. The Company has acquired an exclusive worldwide license agreement for tralesinidase alfa enzyme replacement therapy (TA-ERT) for the treatment of Sanfilippo Syndrome Type B (MPS IIIB). The TA-ERT is a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase (rhNAGLU) with modified human insulin-like growth factor 2 via an amino acid linker. TA-ERT is intended as an enzyme replacement therapy for the treatment of patients with MPS IIIB who lack rhNAGLU enzyme activity. The Company's pipeline also includes Tildacerfont and Cortibon for the treatment of Major Depressive Disorder, SPR202 for the treatment of Congenital Adrenal Hyperplasia and SPR204 for the treatment of Post-Bariatric Hypoglycemia.

Organisation	Spruce Biosciences Inc
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FAQs

What is Spruce Biosciences Inc share price today?

Spruce Biosciences Inc share price today is $10.12 as on September 16, 2025 at 1:28 am IST at the close of the market. Spruce Biosciences Inc share today touched a day high of $0.08 and a low of $0.08.

What is the 52 week high and 52 week low for Spruce Biosciences Inc share?

Spruce Biosciences Inc share touched a 52 week high of $0.61 on October 24, 2024 and a 52 week low of $0.08 on April 28, 2025. Spruce Biosciences Inc stock price today i.e. September 16, 2025 at 1:28 am IST is closed at $10.12,which is -1564.47% down from its 52 week high and 12891.01% up from its 52 week low.

How to invest in Spruce Biosciences Inc Stock (SPRB) from India?

Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
Step 2: Search for Spruce Biosciences Inc on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Spruce Biosciences Inc Shares that will get you 0.1482 shares as per Spruce Biosciences Inc share price of $10.12 per share as on September 16, 2025 at 1:28 am IST.

What is the minimum amount required to buy Spruce Biosciences Inc Stock (SPRB) from India?

Indian investors can start investing in Spruce Biosciences Inc (SPRB) shares with as little as ₹88.141 or $1 (as of September 16, 2025 at 5:21 am IST) using the INDmoney app.
For example: If you want to invest $10 or ₹881.41 in Spruce Biosciences Inc stock (as per the Rupee-Dollar exchange rate as on September 16, 2025 at 5:21 am IST). Based on Spruce Biosciences Inc share’s latest price of $10.12 as on September 16, 2025 at 1:28 am IST, you will get 0.9881 shares of Spruce Biosciences Inc. Learn more about fractional shares .