Spero Therapeutics Inc Stock Performance
as on April 22, 2026 at 3:12 am IST
Day's Low
Day's High
$2.74$2.82
1.79%
Downside
1.08%
Upside

52 Week's Low
52 Week's High
$0.57$3.22
79.57%
Downside
15.41%
Upside

Spero Therapeutics Inc share price movements today
- Previous Close
- $2.84
- Open
- $2.82
- Volume
- 231.9K
- Day's Low - High
- $2.74 - $2.82
- 52 Week Low - High
- $0.57 - $3.22
Spero Therapeutics Inc Historical Returns
- 1 Month Return
- + 19.83 %
- 3 Month Return
- + 20.34 %
- 1 Year Return
- + 291.72 %
- 3 Year Return
- + 67.06 %
- 5 Year Return
- -78.65 %
Spero Therapeutics Inc Stock Fundamentals & Key Indicators
Check Spero Therapeutics Inc market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.
Market Cap
$159.2M
EPS (TTM)
0.67
Dividend Yield
0.00%
Quarterly Earnings Growth YOY
0.75%
PE Ratio (TTM)
18.33
Industry PE ratio
-3.3351693002257337
PEG Ratio
0EBITDA
7.2M
Revenue (TTM)
66.8M
Profit Margin
12.83%
Return On Equity TTM
16.31%
Spero Therapeutics Inc Stock Valuation
Track how Spero Therapeutics Inc P/E has moved over time to understand its valuation trends.
Spero Therapeutics Inc in the last 5 years
Lowest (-6.58x)
June 30, 2023
Industry (-3.34x)
April 21, 2026
Today (18.33x)
April 21, 2026
Highest (19.15x)
September 30, 2024
Today’s Price to Earnings Ratio: 18.33x
Spero Therapeutics Inc vs Peer Comparison
Compare market cap, revenue, PE, and other key metrics of Spero Therapeutics Inc with its industry peers.
Company | Analyst View | Market Cap | 5 Years Return % | PE Ratio | Profit Margin % |
|---|---|---|---|---|---|
| BUY | $159.2M | -78.65% | 18.33 | 12.83% | |
| BUY | $41.3B | 126.09% | 133.47 | 8.45% | |
| BUY | $111.7B | 99.85% | 28.65 | 32.94% | |
| NA | $36.5B | NA | 128.25 | 5.37% | |
| BUY | $79.2B | 47.96% | 18.05 | 31.41% |
Stock Returns calculator for Spero Therapeutics Inc Stock including INR - Dollar returns
The Spero Therapeutics Inc stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.
*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.
Investment Value
₹1,00,000
Spero Therapeutics Inc investment value today
Current value as on today
₹4,25,372
Returns
₹3,25,372
(+325.37%)
Returns from Spero Therapeutics Inc Stock
₹2,87,500 (+287.5%)
Dollar Impact
₹37,872 (+37.87%)
Analyst Recommendation on Spero Therapeutics Inc Stock
Based on 10 analysts
80.00%
Buy
20.00%
Hold
0.00%
Sell
Based on 10 analysts, 80% of analysts recommend a 'BUY' rating for Spero Therapeutics Inc. Average target price of $4
Spero Therapeutics Inc Share Price Target
Get share price movements and forecasts by analysts on Spero Therapeutics Inc.
What analysts predicted
30.25%UPSIDE
Target Price
$4
Current Price
$2.79
Analyzed by
10 Analysts
Target
$4.00
Spero Therapeutics Inc target price $4, a slight upside of 30.25% compared to current price of $2.79. According to 10 analysts rating.
Spero Therapeutics Inc Stock’s Investor Sentiment and Interest
Search interest for Spero Therapeutics Inc Stock has decreased by -43% in the last 30 days, reflecting a downward trend in search activity.
Time period: to
Spero Therapeutics Inc Quarterly Profit & Loss
All numbers in Millions USD
Spero Therapeutics Inc Annual Profit & Loss
All numbers in Millions USD
Spero Therapeutics Inc Quarterly Cash Flow
All numbers in Millions USD
Spero Therapeutics Inc Annual Cash Flow
All numbers in Millions USD
Insights on Spero Therapeutics Inc
Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.
POSITIVE IMPACTBest in 1 Year

In the last 1 year, SPRO has outperformed top 5 stocks with highest market-cap in its industry
POSITIVE IMPACTProfit Spike

Netprofit is up for the last 2 quarters, -7.38M → 31.52M (in $), with an average increase of 123.4% per quarter
POSITIVE IMPACTPrice Rise

In the last 1 year, SPRO stock has moved up by 291.7%
POSITIVE IMPACTRevenue Rich

Revenue is up for the last 2 quarters, 3.04M → 39.65M (in $), with an average increase of 92.3% per quarter
POSITIVE IMPACTBest in 3 Years

In the last 3 years, SPRO has outperformed top 5 stocks with highest market-cap in its industry
About Spero Therapeutics Inc
| Organisation | Spero Therapeutics Inc |
| Headquarters | 675 Massachusetts Avenue, Cambridge, MA, United States, 02139 |
| Industry | Biotechnology |
| CEO | Ms. Esther P. Rajavelu |
| E-voting on shares | Click here to vote |
Key Management of Spero Therapeutics Inc
Name | Title |
|---|---|
Ms. Sheila Finan | Senior Vice President of Controller |
Ms. Esther P. Rajavelu | CEO, President, CFO, Chief Business Officer, Treasurer & Director |
Mr. Timothy Keutzer | Chief Operating Officer |
Mr. John Raymond | Senior Vice President of Finance & Business Operations |
FAQs
What is Spero Therapeutics Inc share price today?
Spero Therapeutics Inc share price today is $2.79 as on . Spero Therapeutics Inc share today touched a day high of $2.82 and a low of $2.74.
What is the 52 week high and 52 week low for Spero Therapeutics Inc share?
Spero Therapeutics Inc share touched a 52 week high of $3.22 on and a 52 week low of $0.57 on . Spero Therapeutics Inc stock price today i.e. is trending at $2.79,which is 13.35% down from its 52 week high and 389.47% up from its 52 week low.
What is Spero Therapeutics Inc's market capitalisation today?
Spero Therapeutics Inc market capitalisation is $0.00T as on .
How to invest in Spero Therapeutics Inc Stock (SPRO) from India?
- Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
- Step 2: Search for Spero Therapeutics Inc on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Spero Therapeutics Inc Shares that will get you 0.5376 shares as per Spero Therapeutics Inc share price of $2.79 per share as on April 21, 2026 at 9:42 pm IST.
What is the minimum amount required to buy Spero Therapeutics Inc Stock (SPRO) from India?
Indian investors can start investing in Spero Therapeutics Inc (SPRO) shares with as little as ₹93.505 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹935.05 in Spero Therapeutics Inc stock (as per the Rupee-Dollar exchange rate as on ).
Based on Spero Therapeutics Inc share’s latest price of $2.79 as on April 21, 2026 at 9:42 pm IST, you will get 3.5842 shares of Spero Therapeutics Inc. Learn more about
fractional shares .
What are the returns that Spero Therapeutics Inc has given to Indian investors in the last 5 years?
Spero Therapeutics Inc stock has given -78.65% share price returns and 22.82% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?