Septerna Inc. (SEPN) Live Share Price, Invest From India

Septerna Inc. Stock Performance

as on June 19, 2026 at 2:15 pm IST

Day's Low
Day's High
$34.51
Day's Price Range
$37.32
$36.17
4.59%
Downside
3.18%
Upside
52 Week's Low
52 Week's High
$9.96
52-Week Price Range
$37.32
$36.17
72.46%
Downside
3.18%
Upside

Septerna Inc. share price movements today

Previous Close: $35.80
Open: $36.25
Volume: 196.9K
Day's Low - High: $34.51 - $37.32
52 Week Low - High: $9.96 - $37.32

Septerna Inc. Historical Returns

1 Month Return: + 36.44 %
3 Month Return: + 48.97 %
1 Year Return: + 244.8 %
3 Year Return: 0 %
5 Year Return: 0 %

Septerna Inc. Stock Fundamentals & Key Indicators

Check Septerna Inc. market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$1.6B

EPS (TTM)

-1.839

Dividend Yield

0.00%

PE Ratio (TTM)

PEG Ratio

Return On Equity TTM

-9.26%

Septerna Inc. vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Septerna Inc. with its industry peers.

Company	Analyst View	Market Cap	5 Years Return %	PE Ratio	Profit Margin %	Dividend Yield %
Septerna Inc.	NA	$1.6B	NA	NA	-49.88%	NA
Alnylam Pharmaceuticals Inc.	BUY	$37.7B	57.21%	71.21	12.55%	NA
Vertex Pharmaceuticals Inc.	BUY	$116.5B	140.42%	27.22	35.51%	NA
Regeneron Pharmaceuticals Inc.	BUY	$63.7B	13.39%	14.85	29.65%	0.58%

Stock Returns calculator for Septerna Inc. Stock including INR - Dollar returns

The Septerna Inc. stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.

Investment Value

₹1,00,000

Septerna Inc. investment value today

Current value as on today

₹3,74,463

Returns

₹2,74,463

(+274.46%)

Returns from Septerna Inc. Stock

₹2,44,805 (+244.8%)

Dollar Impact

₹29,658 (+29.66%)

Indian Investors' Interest in Septerna Inc. Stock

Search interest for Septerna Inc. Stock has increased by 54% in the last 30 days, reflecting an upward trend in search activity.

Time period: May 21, 2026 to June 20, 2026

Change:54% versus previous 30 day period

Septerna Inc. Quarterly Profit & Loss

All numbers in Millions USD

	Dec 2023	Mar 2024	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025	Sep 2025	Dec 2025	Mar 2026
Total Revenue	0	0	0	0	0	0	0	21	24	26
Gross Profit	0	0	0	0	0	0	0	21	24	26
Operating Income	34	-15	-18	-22	-24	-25	-28	2	-16	-13
EBITDA	-13	-13	-16	-20	-20	-21	-24	-9	-10	-7
Interest Expense	-	-	-	-	-	-	-	-	-	-
Depreciation	0	0	0	0	0	0	0	0	0	0
Income Before Tax	35	-14	-16	-20	-20	-21	-24	8	-10	-8
Income Tax Expense	0	0	0	0	0	-	-	-	0	0
Net Income	34	-14	-16	-20	-20	-21	-24	8	-10	-8
Net Profit Margin	29571.19%	-4468.77%	-4443.51%	-11660.80%	-9749.06%	-9806.39%	-20872.27%	38.02%	-44.52%	-32.56%

Septerna Inc. Annual Profit & Loss

All numbers in Millions USD

	Dec 2022	Dec 2023	Dec 2024	Dec 2025
Total Revenue	-	0	1	45
Gross Profit	-	0	1	45
Operating Income	-27	2	-80	-80
EBITDA	-27	-44	-70	-47
Interest Expense	-	-	-	-
Depreciation	0	0	1	1
Income Before Tax	-27	4	-72	-48
Income Tax Expense	-	0	0	0
Net Income	-27	4	-71	-48
Net Profit Margin	0.00%	2768.21%	-6678.88%	-106.37%

Septerna Inc. Quarterly Cash Flow

All numbers in Millions USD

	Mar 2024	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025	Sep 2025	Dec 2025	Mar 2026
Net Income	-14	-16	-20	-20	-21	-24	8	-10	-8
Operating Cash Flow	-16	-12	-16	-20	-23	-20	168	-14	-25
Investing Cash Flow	9	-12	-24	-133	-4	0	-38	-185	-23
Financing Cash Flow	-	74	-1	304	0	0	0	1	0
Change in Cash	-7	131	-42	149	-28	-20	130	-199	-49

Septerna Inc. Annual Cash Flow

All numbers in Millions USD

	Dec 2023	Dec 2024	Dec 2025
Net Income	4	-71	-48
Operating Cash Flow	-38	-67	110
Investing Cash Flow	22	-160	-229
Financing Cash Flow	74	377	1
Change in Cash	57	149	-117

Global Institutional Holdings in Septerna Inc.

Funds	Holdings
The Goldman Sachs Group Inc	6.45%
PRIMECAP Management Company	2.33%
Kalehua Capital Management LLC	0.87%
First Light Asset Management, LLC	1.63%
RA Capital Management, LLC	15.52%

See all

Insights on Septerna Inc.

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

POSITIVE IMPACT
Best in 1 Year
In the last 1 year, SEPN has outperformed top 5 stocks with highest market-cap in its industry
POSITIVE IMPACT
Price Rise
In the last 1 month, SEPN stock has moved up by 29.1%

About Septerna Inc.

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric modulator (NAM) for chronic spontaneous urticaria and other mast cell diseases; and TSHR Program, an oral small molecule TSHR NAM for graves' disease and thyroid eye disease. In addition, it focuses on other therapeutic areas, including neurology, women's health, cardiovascular disease, and respiratory disease. It has global collaboration and license agreement with Novo Nordisk to discover, develop and commercialize multiple potential oral small molecule therapies for metabolic-related diseases based on certain specified molecular targets. The company was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. Septerna, Inc. was incorporated in 2019 and is headquartered in South San Francisco, California.

Organisation	Septerna Inc.
Headquarters	250 East Grand Avenue, South San Francisco, CA, United States, 94080
Industry	Biotechnology
CEO	Dr. Jeffrey T. Finer M.D., Ph.D.
E-voting on shares	Click here to vote

Key Management of Septerna Inc.

Name	Title
Dr. Jeffrey T. Finer M.D., Ph.D.	Co-Founder, CEO & Director
Mr. Gilbert M. Labrucherie C.F.A., J.D.	Chief Financial Officer
Dr. Arthur Christopoulos BPHARM, Ph.D.	Co-Founder and Member of Cross-Functional Scientific & Drug Discovery Advisory Board
Dr. Patrick Sexton Ph.D.	Co-Founder and Member of Cross-Functional Scientific & Drug Discovery Advisory Board
Mr. Richard Hansen Ph.D.	Vice President of Technology
Mr. Mark A. Wilson J.D.	Chief Legal Officer
Mr. George Xu Ph.D.	Senior Director of Corporate Development & Portfolio Strategy
Ms. Elizabeth P. Bhatt M.B.A., M.S.	President & COO
Dr. Robert J. Lefkowitz M.D.	Co-Founder and Member of Cross-Functional Scientific & Drug Discovery Advisory Board
Ms. Samira Shaikhly	Chief People Officer

FAQs

What is Septerna Inc. share price today?

Septerna Inc. share price today is $36.17 as on June 19, 2026 at 8:45 am IST at the close of the market. Septerna Inc. share today touched a day high of $37.32 and a low of $34.51.

What is the 52 week high and 52 week low for Septerna Inc. share?

Septerna Inc. share touched a 52 week high of $37.32 on June 18, 2026 and a 52 week low of $9.96 on June 20, 2025. Septerna Inc. stock price today i.e. June 19, 2026 at 8:45 am IST is closed at $36.17,which is 3.08% down from its 52 week high and 263.15% up from its 52 week low.

What is Septerna Inc.'s market capitalisation today?

Septerna Inc. market capitalisation is $0.00T as on June 19, 2026 at 8:45 am IST.

How to invest in Septerna Inc. Stock (SEPN) from India?

Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
Step 2: Search for Septerna Inc. on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Septerna Inc. Shares that will get you 0.0415 shares as per Septerna Inc. share price of $36.17 per share as on June 19, 2026 at 8:45 am IST.

What is the minimum amount required to buy Septerna Inc. Stock (SEPN) from India?

Indian investors can start investing in Septerna Inc. (SEPN) shares with as little as ₹94.31 or $1 (as of June 20, 2026 at 1:42 pm IST) using the INDmoney app.
For example: If you want to invest $10 or ₹943.10 in Septerna Inc. stock (as per the Rupee-Dollar exchange rate as on June 20, 2026 at 1:42 pm IST). Based on Septerna Inc. share’s latest price of $36.17 as on June 19, 2026 at 8:45 am IST, you will get 0.2765 shares of Septerna Inc.. Learn more about fractional shares .