Pyxis Oncology share price logo

Pyxis Oncology

NASDAQ: PYXS

Small Cap

$3.21

-0.12

(-3.60%)

as on

Pyxis Oncology Stock Performance

as on September 22, 2026 at 6:59 am IST

  • Day's Low

    Day's High

    $3.20
    $3.35
    downward going graph

    0.31%

    Downside

    4.36%

    Upside

    downward going graph
  • 52 Week's Low

    52 Week's High

    $1.03
    $5.55
    downward going graph

    67.91%

    Downside

    72.90%

    Upside

    downward going graph

Pyxis Oncology share price movements today

Previous Close
$3.33
Open
$3.35
Volume
901.5K
Market Cap
$277.7M
Day's Low - High
$3.20 - $3.35
52 Week Low - High
$1.03 - $5.55

Pyxis Oncology Historical Returns

1 Month Return
+ 8.12 %
3 Month Return
+ 64.04 %
1 Year Return
+ 48 %
3 Year Return
+ 91.38 %
5 Year Return
0 %

Pyxis Oncology Stock Fundamentals & Key Indicators

Check Pyxis Oncology market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$277.7M

EPS (TTM)

-1.41

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.00%

PE Ratio (TTM)

-2.36

Industry PE ratio

-6.94

PEG Ratio

-0.3097370594556825

EBITDA

-83.4M

Revenue (TTM)

11.0M

Profit Margin

99.76%

Return On Equity TTM

-215.23%

Pyxis Oncology Stock Valuation

Track how Pyxis Oncology P/E has moved over time to understand its valuation trends.

Pyxis Oncology in the last 5 years

  • Overview

  • Trends

Lowest (-4.65x)

December 31, 2021

Industry (-6.94x)

December 31, 2025

Today (-0.90x)

December 31, 2025

Highest (-0.37x)

December 31, 2022

LowHigh

Today’s Price to Earnings Ratio: -0.90x

Pyxis Oncology vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Pyxis Oncology with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %Dividend Yield %
StrongBuy$277.7MNA-2.3699.76%0.00%
Neutral$61.5B-64.51%-19.3-12.57%0.00%
StrongBuy$130.1B174.21%29.8186.04%0.00%
Buy$80.8B21.32%18.4884.86%0.47%

Stock Returns calculator for Pyxis Oncology Stock including INR - Dollar returns

The Pyxis Oncology stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.

Investment Value

₹1,00,000

  • 1Y

  • 3Y

Pyxis Oncology investment value today

Current value as on today

₹1,54,787

Returns

₹54,787

(+54.79%)

Returns from Pyxis Oncology Stock

₹42,667 (+42.67%)

Dollar Impact

₹12,121 (+12.12%)

Analyst Recommendation on Pyxis Oncology Stock

Based on 8 analysts

BUY

87.50%

Buy

12.50%

Hold

0.00%

Sell

Based on 8 analysts, 87.5% of analysts recommend a 'BUY' rating for Pyxis Oncology. Average target price of $8.44

Pyxis Oncology Share Price Target

Get share price movements and forecasts by analysts on Pyxis Oncology.

What analysts predicted

61.97%UPSIDE

Target Price

$8.44

Current Price

$3.21

Analyzed by

8 Analysts

Target

$8.44

Pyxis Oncology target price $8.44, a slight upside of 61.97% compared to current price of $3.21. According to 8 analysts rating.

Indian Investors' Interest in Pyxis Oncology Stock

Search interest for Pyxis Oncology Stock has increased by 5% in the last 30 days, reflecting an upward trend in search activity.

Time period: to

Change:5% versus previous 30 day period

Pyxis Oncology Quarterly Profit & Loss

All numbers in Millions USD

Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Mar 2026
Jun 2026
Total Revenue
16
-
-
-
-
2
-
11
-
-
Gross Profit
15
-
-
-
-
2
-
11
0
-
Operating Income
-5
-20
-23
-40
-22
-19
-23
-18
-24
-25
EBITDA
-2
-16
-20
-18
-20
-17
-21
-14
-22
-25
Interest Expense
-
-
-
-
-
-
-
-
-
-
Depreciation
1
0
0
0
0
0
0
2
0
0
Income Before Tax
-3
-17
-21
-37
-21
-18
-22
-17
-23
-25
Income Tax Expense
-
-
-
-2
-
0
-
1
-
-
Net Income
-3
-17
-21
-35
-21
-18
-22
-18
-23
-25
Net Profit Margin
97.06%
0.00%
0.00%
0.00%
0.00%
100.00%
0.00%
103.91%
0.00%
0.00%

Pyxis Oncology Annual Profit & Loss

All numbers in Millions USD

Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Total Revenue
-
-
-
-
-
16
13
Gross Profit
-
0
-
-
-
15
11
Operating Income
-2
-12
-69
-123
-82
-89
-84
EBITDA
-2
-12
-75
-120
-71
-65
-73
Interest Expense
-
-
-
-
-
-
-
Depreciation
-
0
0
0
1
2
4
Income Before Tax
-2
-12
-75
-120
-73
-79
-78
Income Tax Expense
-
-
-
-
-
-2
1
Net Income
-2
-12
-75
-120
-73
-77
-79
Net Profit Margin
0.00%
0.00%
0.00%
0.00%
0.00%
97.06%
82.77%

Pyxis Oncology Quarterly Cash Flow

All numbers in Millions USD

Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Mar 2026
Jun 2026
Net Income
-3
-17
-21
-35
-21
-18
-22
-18
-23
-25
Operating Cash Flow
-20
-3
-14
-19
-22
-17
-13
-10
-26
-18
Investing Cash Flow
-18
0
0
26
15
15
11
16
16
21
Financing Cash Flow
57
0
1
0
-
0
0
0
0
9
Change in Cash
18
-2
-13
7
-6
-2
-1
6
-9
13

Pyxis Oncology Annual Cash Flow

All numbers in Millions USD

Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Net Income
-2
-12
-75
-120
-73
-77
-79
Operating Cash Flow
-2
-10
-35
-89
-70
-57
-63
Investing Cash Flow
-
-1
0
-6
-104
8
58
Financing Cash Flow
21
0
304
0
5
59
0
Change in Cash
19
-11
268
-95
-169
9
-4

Mutual Funds that own Pyxis Oncology Stock

Check out the Mutual Funds with significant holdings in Pyxis Oncology.

Funds
Holdings
Shares Held
VANGUARD INDEX FUNDS
2.350028%
1960113
Fidelity Concord Street Trust
0.565211%
471432
Bridgeway Funds, Inc.
0.083996%
70060
VANGUARD VALLEY FORGE FUNDS
0.03221%
26866
VANGUARD INSTITUTIONAL INDEX FUNDS
0.031951%
26650

Global Institutional Holdings in Pyxis Oncology

Funds
Holdings
Vanguard
2.65%
Joseph Edelman
1.41%
iShares
0.93%
Michael Rockefeller
0.63%
Richard Driehaus
0.5%

Pyxis Oncology News & Key Events

  • img

    Today's Timeline - 09 September

    Wed, 05:11 PM

    -

    Pyxis Oncology announces updated Phase 1 study results for micvotabart pelidotin, showing promising efficacy and safety in head and neck cancer.

Insights on Pyxis Oncology

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Best in 3 Years

    img

    In the last 3 years, PYXS has outperformed top 5 stocks with highest market-cap in its industry

  • imgPOSITIVE IMPACT

    Price Rise

    img

    In the last 1 month, PYXS stock has moved up by 8.1%

  • imgNO EFFECT

    Against Peers

    img

    In the last 1 year, Moderna, Inc. Common Stock has given 510.3% return, outperforming this stock by 462.3%

About Pyxis Oncology

Pyxis Oncology, Inc. operates as a preclinical biopharmaceutical company focused on developing novel therapeutic approaches to combat various forms of cancer. Its investigational immune-oncology pipeline includes PYX-106, a fully human immunoglobulin G1 (IgG1) antibody designed to target siglec-15, which is being explored for its potential efficacy against thyroid cancer, head and neck squamous cell carcinoma, non-small cell lung cancer (NSCLC), and other solid tumors. Additionally, PYX-102 is an immune-therapeutic currently under investigation for the treatment of solid tumors. The company's portfolio also features a range of investigational antibody-drug conjugate (ADC) candidates: PYX-201, a novel ADC being developed for NSCLC, breast cancer, and other solid tumors; PYX-202, another novel ADC aimed at small cell lung cancer (SCLC), soft tissue sarcoma, and other solid tumors; and PYX-203, an ADC undergoing evaluation for acute myeloid leukemia and myeloid dysplastic syndrome. Pyxis Oncology was founded in 2018 and is based in Cambridge, Massachusetts.
OrganisationPyxis Oncology
Headquarters321 Harrison Avenue, Boston, MA, 02118, US
IndustryBiotechnology
CEOThomas Civik
E-voting on sharesClick here to vote

Key Management of Pyxis Oncology

Name

Title

Dr. Balu N. Balasubramanian Ph.D.

Interim Chief Technology Officer

Dr. Charles T. Gombar Ph.D.

Senior Vice President of Portfolio & Program Management

Dr. Shui He Ph.D.

Head of Biometrics

Dr. Hongwei Wang M.D., Ph.D.

Head of ADC Development & Clinical Strategy

Dr. Supriya Roth Ph.D.

Head of Commercial Development

Dr. Marsha Crochiere Ph.D.

Head of Translational Medicine & Research

Mr. Thomas Civik

Interim CEO & Director

Mr. Jitendra Wadhane C.A., CPA

Chief Accounting Officer, Senior VP of Finance, Corporate Controller & Principal Financial Officer

Donna Regalado

Head of Human Resources

Dr. Michael Bui

Senior Vice President of Global Regulatory Affairs

FAQs

What is Pyxis Oncology share price today?

Pyxis Oncology share price today is $3.21 as on at the close of the market. Pyxis Oncology share today touched a day high of $3.35 and a low of $3.20.

What is the 52 week high and 52 week low for Pyxis Oncology share?

Pyxis Oncology share touched a 52 week high of $5.55 on and a 52 week low of $1.03 on . Pyxis Oncology stock price today i.e. is closed at $3.21,which is 42.16% down from its 52 week high and 211.65% up from its 52 week low.

What is Pyxis Oncology's market capitalisation today?

Pyxis Oncology market capitalisation is $0.00T as on .

How to invest in Pyxis Oncology Stock (PYXS) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Pyxis Oncology on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Pyxis Oncology Shares that will get you 0.4673 shares as per Pyxis Oncology share price of $3.21 per share as on September 22, 2026 at 1:29 am IST.

What is the minimum amount required to buy Pyxis Oncology Stock (PYXS) from India?

Indian investors can start investing in Pyxis Oncology (PYXS) shares with as little as ₹95.805 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹958.05 in Pyxis Oncology stock (as per the Rupee-Dollar exchange rate as on ). Based on Pyxis Oncology share’s latest price of $3.21 as on September 22, 2026 at 1:29 am IST, you will get 3.1153 shares of Pyxis Oncology. Learn more about fractional shares .