Prime Medicine, Inc. share price logo

Prime Medicine, Inc. Share Price

NASDAQ: PRME

Small Cap

$3.75

-0.10

(-2.60%)

as on

Prime Medicine, Inc. Stock Performance

as on December 6, 2025 at 2:29 am IST

  • Day's Low

    Day's High

    $3.68
    $3.94
    downward going graph

    1.87%

    Downside

    5.07%

    Upside

    downward going graph

  • 52 Week's Low

    52 Week's High

    $1.11
    $6.94
    downward going graph

    70.40%

    Downside

    85.07%

    Upside

    downward going graph

Prime Medicine, Inc. share price movements today

Previous Close
$3.85
Open
$3.88
Volume
2.4M
Day's Low - High
$3.68 - $3.94
52 Week Low - High
$1.11 - $6.94

Prime Medicine, Inc. Historical Returns

1 Month Return
-1.84 %
3 Month Return
-3.86 %
1 Year Return
+ 14.37 %
3 Year Return
-78.37 %
5 Year Return
0 %

Prime Medicine, Inc. Stock Fundamentals & Key Indicators

Check Prime Medicine, Inc. market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$675.1M

EPS (TTM)

-1.2719

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.00%

PE Ratio (TTM)

0

PEG Ratio

0

EBITDA

-196.8M

Revenue (TTM)

6.0M

Profit Margin

0.00%

Return On Equity TTM

-112.34%

Prime Medicine, Inc. vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Prime Medicine, Inc. with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %
Prime Medicine, Inc. image
Prime Medicine, Inc.
BUY$675.1MNANA0.00%
Insmed Incorporated image
Insmed Incorporated
BUY$43.5B418.42%-16.34-264.83%
Alnylam Pharmaceuticals, Inc. image
Alnylam Pharmaceuticals, Inc.
BUY$60.5B257.77%1431.621.36%
Vertex Pharmaceuticals Incorporated image
Vertex Pharmaceuticals Incorporated
BUY$116.8B98.18%32.0531.35%
Regeneron Pharmaceuticals, Inc. image
Regeneron Pharmaceuticals, Inc.
BUY$76.1B44.5%17.2132.13%

Stock Returns calculator for Prime Medicine, Inc. Stock including INR - Dollar returns

The Prime Medicine, Inc. stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.

Investment Value

₹1,00,000

  • 1Y

  • 3Y

Prime Medicine, Inc. investment value today

Current value as on today

₹1,20,818

Returns

₹20,818

(+20.82%)

Returns from Prime Medicine, Inc. Stock

₹14,679 (+14.68%)

Dollar Returns*

₹6,139 (+6.14%)

Analyst Recommendation on Prime Medicine, Inc. Stock

Based on 17 analysts

BUY

76.47%

Buy

23.53%

Hold

0.00%

Sell

Based on 17 analysts, 76.47% of analysts recommend a 'BUY' rating for Prime Medicine, Inc.. Average target price of $6.46

Prime Medicine, Inc. Share Price Target

Get share price movements and forecasts by analysts on Prime Medicine, Inc..

What analysts predicted

41.95%UPSIDE

Target Price

$6.46

Current Price

$3.75

Analyzed by

17 Analysts

Target

$6.46

Prime Medicine, Inc. target price $6.46, a slight upside of 41.95% compared to current price of $3.75. According to 17 analysts rating.

Prime Medicine, Inc. Stock’s Investor Sentiment and Interest

Search interest for Prime Medicine, Inc. Stock has increased by 7% in the last 30 days, reflecting an upward trend in search activity.

Time period: to

Change:7% versus previous 30 day period

Prime Medicine, Inc. Quarterly Profit & Loss

All numbers in Millions USD

Jun 2023
Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Total Revenue
-
-
25
0
37
0
2
1
1
1
Gross Profit
-4
-4
-1
0
-1
0
2
1
0
-42
Operating Income
-45
-51
-68
-48
-55
-54
-44
-52
-53
-53
EBITDA
-44
-50
-53
-47
-54
-52
-42
-50
-51
-48
Interest Expense
-
-
0
-
-
-
-
-
-
-
Depreciation
1
1
1
1
1
1
1
1
1
1
Income Before Tax
-42
-50
-65
-45
-55
-52
-42
-51
-52
-50
Income Tax Expense
0
0
0
0
0
-
-
-
-
-
Net Income
-42
-50
-65
-45
-55
-52
-42
-51
-52
-50
Net Profit Margin
0.00%
0.00%
-255.50%
-7742.98%
-146.47%
-25128.23%
-1936.60%
-3568.78%
-4716.68%
-4129.14%

Prime Medicine, Inc. Annual Profit & Loss

All numbers in Millions USD

Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Total Revenue
5
-
5
-
2
Gross Profit
2
-4
-12
-4
2
Operating Income
0
-84
-116
-204
-202
EBITDA
0
-83
-114
-186
-196
Interest Expense
10
81
12
-
-
Depreciation
0
0
2
4
6
Income Before Tax
-1
-165
-122
-198
-195
Income Tax Expense
1
0
0
0
-
Net Income
-3
-165
-121
-198
-195
Net Profit Margin
-65.45%
0.00%
-2338.21%
0.00%
-6566.61%

Prime Medicine, Inc. Quarterly Cash Flow

All numbers in Millions USD

Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Net Income
-50
-65
-45
-55
-52
-42
-51
-52
-50
Operating Cash Flow
-39
-43
-67
-45
-25
16
-48
-41
-35
Investing Cash Flow
-37
41
-37
6
50
48
-47
2
-92
Financing Cash Flow
0
0
157
0
38
0
6
0
144
Change in Cash
-76
-2
52
-38
62
64
-90
-38
17

Prime Medicine, Inc. Annual Cash Flow

All numbers in Millions USD

Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Net Income
-3
-165
-121
-198
-195
Operating Cash Flow
-5
-34
-131
-165
-122
Investing Cash Flow
-1
-73
-47
18
68
Financing Cash Flow
34
269
181
0
195
Change in Cash
28
161
2
-146
141

Global Institutional Holdings in Prime Medicine, Inc.

Funds
Holdings
Alphabet Inc
8.45%
T. Rowe Price Investment Management,Inc.
3.64%
BlackRock Inc
2.52%
FMR Inc
2.1%
Vanguard Group Inc
2.03%
See all

Insights on Prime Medicine, Inc.

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Price Rise

    img

    In the last 6 months, PRME stock has moved up by 121.3%

  • imgNO EFFECT

    Against Peers

    img

    In the last 3 years, Insmed Incorporated has given 995.0% return, outperforming this stock by 1073.4%

  • imgNO EFFECT

    Against Peers

    img

    In the last 1 year, Insmed Incorporated has given 170.6% return, outperforming this stock by 156.2%

About Prime Medicine, Inc.

Prime Medicine, Inc. is a biotechnology company engaged in creating and delivering gene editing therapies to patients. It deploys its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated one-time curative genetic therapies. It is advancing a set of high-value programs across its core areas of focus (hematology, immunology and oncology, liver, and lung). These include ex vivo hematopoietic stem cell (HSC) programs for the treatment of p47phox chronic granulomatous disease CGD and X-linked CGD; a lipid nanoparticle (LNP) Prime Editor for the treatment of Wilson’s Disease; a LNP or adeno-associated virus Prime Editors for the treatment of cystic fibrosis; and ex vivo T-cell therapies. PM359, its product candidate within its hematology, immunology and oncology area of focus, targets the p47phox variant of CGD. Its PM577 comprises a Prime Editor encapsulated as RNA cargo in a liver-targeted LNP.
OrganisationPrime Medicine, Inc.
Headquarters60 First Street, Cambridge, MA, United States, 02141
IndustryHealthcare
CEODr. Allan Reine M.D.
E-voting on sharesClick here to vote

Key Management of Prime Medicine, Inc.

Name

Title

Dr. Allan Reine M.D.

CEO & Director

Dr. Andrew Anzalone M.D., Ph.D.

Co-Founder

Mr. Ryan E. Brown J.D.

Chief Legal Officer

Ms. Niamh Alix

Chief Human Resources Officer

Mr. Mohammed Asmal M.D., Ph.D.

Senior VP & Head of Clinical

Dr. Matthew J. Hawryluk M.B.A., Ph.D.

Chief Business Officer

Mr. Jeffrey D. Marrazzo M.B.A., M.P.A.

Executive Chair

Dr. Keith Michael Gottesdiener M.D., Ph.D.

Consultant

Dr. David R. Liu Ph.D.

Co-Founder & Member of Scientific Advisory Board

Dr. Ann L. Lee Ph.D.

Chief Technical Officer

FAQs

What is Prime Medicine, Inc. share price today?

Prime Medicine, Inc. share price today is $3.75 as on at the close of the market. Prime Medicine, Inc. share today touched a day high of $3.94 and a low of $3.68.

What is the 52 week high and 52 week low for Prime Medicine, Inc. share?

Prime Medicine, Inc. share touched a 52 week high of $6.94 on and a 52 week low of $1.11 on . Prime Medicine, Inc. stock price today i.e. is closed at $3.75,which is 45.97% down from its 52 week high and 237.84% up from its 52 week low.

What is Prime Medicine, Inc.'s market capitalisation today?

Prime Medicine, Inc. market capitalisation is $0.00T as on .

How to invest in Prime Medicine, Inc. Stock (PRME) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Prime Medicine, Inc. on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Prime Medicine, Inc. Shares that will get you 0.4000 shares as per Prime Medicine, Inc. share price of $3.75 per share as on December 6, 2025 at 2:29 am IST.

What is the minimum amount required to buy Prime Medicine, Inc. Stock (PRME) from India?

Indian investors can start investing in Prime Medicine, Inc. (PRME) shares with as little as ₹90.066 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹900.66 in Prime Medicine, Inc. stock (as per the Rupee-Dollar exchange rate as on ). Based on Prime Medicine, Inc. share’s latest price of $3.75 as on December 6, 2025 at 2:29 am IST, you will get 2.6667 shares of Prime Medicine, Inc.. Learn more about fractional shares .