Oruka Therapeutics share price logo

Oruka Therapeutics

NASDAQ: ORKA

Mid Cap

$84.04

-0.42

(-0.50%)

as on

Oruka Therapeutics Stock Performance

as on September 29, 2026 at 6:59 am IST

  • Day's Low

    Day's High

    $83.22
    $85.95
    downward going graph

    0.98%

    Downside

    2.27%

    Upside

    downward going graph
  • 52 Week's Low

    52 Week's High

    $15.77
    $115.52
    downward going graph

    81.24%

    Downside

    37.45%

    Upside

    downward going graph

Oruka Therapeutics share price movements today

Previous Close
$84.46
Open
$83.68
Volume
656.1K
Market Cap
$5.6B
Day's Low - High
$83.22 - $85.95
52 Week Low - High
$15.77 - $115.52

Oruka Therapeutics Historical Returns

1 Month Return
-7.33 %
3 Month Return
-6.78 %
1 Year Return
+ 455.66 %
3 Year Return
0 %
5 Year Return
0 %

Oruka Therapeutics Stock Fundamentals & Key Indicators

Check Oruka Therapeutics market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$5.6B

EPS (TTM)

-2.47

Dividend Yield

0.00%

PE Ratio (TTM)

-34.19

Industry PE ratio

-12.67

PEG Ratio

-0.6307202260476119

Return On Equity TTM

-20.76%

Oruka Therapeutics Stock Valuation

Track how Oruka Therapeutics P/E has moved over time to understand its valuation trends.

Oruka Therapeutics in the last 5 years

  • Overview

  • Trends

Lowest (-41.29x)

December 31, 2022

Today (-13.12x)

December 31, 2025

Industry (-12.67x)

December 31, 2025

Highest (-3.89x)

December 31, 2024

LowHigh

Today’s Price to Earnings Ratio: -13.12x

Oruka Therapeutics vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Oruka Therapeutics with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %Dividend Yield %
StrongBuy$5.6BNA-34.190.00%0.00%
StrongBuy$43.9B615.18%-23.130.00%0.00%
Neutral$79.4B-48.24%-24.92-12.57%0.00%
StrongBuy$133.4B189.75%30.3886.04%0.00%
Buy$81.1B30.25%18.8284.86%0.47%

Stock Returns calculator for Oruka Therapeutics Stock including INR - Dollar returns

The Oruka Therapeutics stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.

Investment Value

₹1,00,000

  • 1Y

Oruka Therapeutics investment value today

Current value as on today

₹5,98,246

Returns

₹4,98,246

(+498.25%)

Returns from Oruka Therapeutics Stock

₹4,52,895 (+452.89%)

Dollar Impact

₹45,352 (+45.35%)

Analyst Recommendation on Oruka Therapeutics Stock

Based on 10 analysts

BUY

100.00%

Buy

0.00%

Hold

0.00%

Sell

Based on 10 analysts, 100% of analysts recommend a 'BUY' rating for Oruka Therapeutics. Average target price of $159.111111111111

Indian Investors' Interest in Oruka Therapeutics Stock

Search interest for Oruka Therapeutics Stock has decreased by -55% in the last 30 days, reflecting a downward trend in search activity.

Time period: to

Change:-55% versus previous 30 day period

Oruka Therapeutics Quarterly Profit & Loss

All numbers in Millions USD

Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Mar 2026
Jun 2026
Total Revenue
-
-
-
-
-
-
-
-
-
-
Gross Profit
0
-
-
-
-
-
-
0
0
0
Operating Income
-2
-21
-29
-38
-25
-28
-34
-34
-36
-50
EBITDA
-1
-22
-28
-37
-20
-24
-30
-29
-31
-50
Interest Expense
-
-
0
-
-
-
-
-
-
-
Depreciation
0
0
-
0
0
0
0
0
0
0
Income Before Tax
-2
-22
-28
-33
-20
-24
-30
-29
-31
-41
Income Tax Expense
-
-
-
-
-
-
-
-
-
-
Net Income
-2
-22
-28
-33
-20
-24
-30
-29
-31
-41
Net Profit Margin
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%

Oruka Therapeutics Annual Profit & Loss

All numbers in Millions USD

Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2024
Dec 2025
Total Revenue
-
-
-
-
-
-
-
-
Gross Profit
0
0
0
0
0
0
0
0
Operating Income
-18
-8
-5
-9
-19
-9
-88
-122
EBITDA
-18
-7
-5
-9
-19
-9
-82
-105
Interest Expense
-
-
0
0
-
-
1
-
Depreciation
0
0
0
0
0
0
0
0
Income Before Tax
-18
-7
-5
-9
-19
-9
-83
-105
Income Tax Expense
0
0
0
0
-
-
-
-
Net Income
-18
-7
-5
-9
-19
-9
-83
-105
Net Profit Margin
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%
0.00%

Oruka Therapeutics Quarterly Cash Flow

All numbers in Millions USD

Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Mar 2026
Jun 2026
Net Income
-7
-2
-28
-25
-20
-24
-30
-29
-31
-41
Operating Cash Flow
0
-2
-34
-18
-20
-23
-21
-22
-23
-33
Investing Cash Flow
-
-
0
-329
42
4
-122
-22
-14
-410
Financing Cash Flow
27
0
450
0
-
0
169
0
40
663
Change in Cash
27
-2
377
-349
21
-18
25
-44
2
218

Oruka Therapeutics Annual Cash Flow

All numbers in Millions USD

Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2024
Dec 2025
Net Income
-18
-7
-5
-9
-19
-9
-83
-105
Operating Cash Flow
-17
-8
-4
-7
-18
-10
-57
-88
Investing Cash Flow
12
3
0
0
0
0
-330
-96
Financing Cash Flow
5
3
6
48
23
-
449
170
Change in Cash
1
-2
1
40
4
-10
24
-14

Mutual Funds that own Oruka Therapeutics Stock

Check out the Mutual Funds with significant holdings in Oruka Therapeutics.

Funds
Holdings
Shares Held
VANGUARD INDEX FUNDS
2.736763%
1812003
Fidelity Select Portfolios
2.238785%
1482293
Fidelity Securities Fund
2.20941%
1462844
Fidelity Advisor Series VII
1.754102%
1161386
Fidelity Mt. Vernon Street Trust
0.960587%
636002

Global Institutional Holdings in Oruka Therapeutics

Funds
Holdings
Peter Harwin
5.6%
Vanguard
4.32%
iShares
3.76%
SPDR
2.82%
VANGUARD INDEX FUNDS
2.74%

Oruka Therapeutics News & Key Events

  • img

    Today's Timeline - 23 September

    Wed, 04:41 PM

    -

    Oruka Therapeutics announces positive Week 28 results for ORKA-001, showing significant efficacy in psoriasis treatment.

Insights on Oruka Therapeutics

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Price Rise

    img

    In the last 1 year, ORKA stock has moved up by 455.7%

  • imgPOSITIVE IMPACT

    Best in 3 Years

    img

    In the last 3 years, ORKA has outperformed top 5 stocks with highest market-cap in its industry

  • imgNO EFFECT

    Against Peers

    img

    In the last 1 year, Moderna, Inc. Common Stock has given 712.1% return, outperforming this stock by 256.4%

About Oruka Therapeutics

Oruka Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psoriasis (PsO), and other inflammatory and immunology (I&I) indications. Its lead products include ORKA-001 that targets p19 subunit of interleukin-23, which is in phase 2a trial for the treatment of PsO; and ORKA-002 that targets interleukin-17A and interleukin-17F, which is in phase 2 trial for the treatment of PsO, psoriatic arthritis, and other conditions. The company also develops ORKA-003 for targeting an undisclosed pathway; and ORKA-021, a sequential combination regimen of ORKA-002 and ORKA-001. Oruka Therapeutics, Inc. is headquartered in Menlo Park, California.
OrganisationOruka Therapeutics
Headquarters855 Oak Grove Avenue, Menlo Park, CA, 94025, US
IndustryBiotechnology
CEOLawrence Otto Klein
E-voting on sharesClick here to vote

Key Management of Oruka Therapeutics

Name

Title

Mr. Larry Todd Edwards

Chief Commercial Officer

Mr. Paul T. Quinlan

General Counsel & Secretary

Ms. Laura Sandler

Chief Operating Officer

Mr. Alan Lada

VP of IR & Capital Markets

Mr. Christopher Finch

Senior VP and Head of Business Development & Strategy

Dr. Rajiv Panwar

Senior VP and Head of Chemistry, Manufacturing & Controls

Dr. Lawrence Otto Klein Ph.D.

President, CEO & Director

Dr. Joana Goncalves M.D.

Chief Medical Officer

Mr. Arjun Agarwal CPA

Senior VP of Finance & Treasurer

FAQs

What is Oruka Therapeutics share price today?

Oruka Therapeutics share price today is $84.04 as on at the close of the market. Oruka Therapeutics share today touched a day high of $85.95 and a low of $83.22.

What is the 52 week high and 52 week low for Oruka Therapeutics share?

Oruka Therapeutics share touched a 52 week high of $115.52 on and a 52 week low of $15.77 on . Oruka Therapeutics stock price today i.e. is closed at $84.04,which is 27.25% down from its 52 week high and 432.91% up from its 52 week low.

What is Oruka Therapeutics's market capitalisation today?

Oruka Therapeutics market capitalisation is $0.01T as on .

How to invest in Oruka Therapeutics Stock (ORKA) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Oruka Therapeutics on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Oruka Therapeutics Shares that will get you 0.0178 shares as per Oruka Therapeutics share price of $84.04 per share as on September 29, 2026 at 1:29 am IST.

What is the minimum amount required to buy Oruka Therapeutics Stock (ORKA) from India?

Indian investors can start investing in Oruka Therapeutics (ORKA) shares with as little as ₹95.980003356934 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹959.80 in Oruka Therapeutics stock (as per the Rupee-Dollar exchange rate as on ). Based on Oruka Therapeutics share’s latest price of $84.04 as on September 29, 2026 at 1:29 am IST, you will get 0.1190 shares of Oruka Therapeutics. Learn more about fractional shares .