Orchestra Biomed Holdings Inc Share Price

NASDAQ: OBIO

Small Cap

$2.58

+0.01

(+0.39%)

as on September 16, 2025 at 1:29 am IST

$₹

Orchestra Biomed Holdings Inc Stock Performance

as on September 16, 2025 at 1:29 am IST

Day's Low
Day's High
$2.54
Day's Price Range
$2.68
$2.58
1.55%
Downside
3.88%
Upside
52 Week's Low
52 Week's High
$2.37
52-Week Price Range
$6.5
$2.58
8.14%
Downside
151.94%
Upside

Orchestra Biomed Holdings Inc share price movements today

Previous Close: $2.57
Open: $2.58
Volume: 736.5K
Day's Low - High: $2.54 - $2.68
52 Week Low - High: $2.37 - $6.5

Orchestra Biomed Holdings Inc Historical Returns

1 Month Return: + 0.19 %
3 Month Return: -16.83 %
1 Year Return: -55.84 %
3 Year Return: 0 %
5 Year Return: 0 %

Orchestra Biomed Holdings Inc Stock Fundamentals & Key Indicators

Check Orchestra Biomed Holdings Inc market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$138.7M

EPS (TTM)

-1.8928

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.00%

PE Ratio (TTM)

P/B Ratio

PEG Ratio

EBITDA

-70.9M

Revenue (TTM)

2.9M

Profit Margin

0.00%

Return On Equity TTM

17004500.00%

Orchestra Biomed Holdings Inc vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Orchestra Biomed Holdings Inc with its industry peers.

Company	Analyst View	Market Cap	5 Years Return %	PE Ratio	Profit Margin %
Orchestra Biomed Holdings Inc	BUY	$138.7M	NA	NA	0.00%
Alnylam Pharmaceuticals, Inc.	BUY	$61.1B	256.98%	-505.15	-12.96%
Beone Medicines Ltd	NA	$38.7B	NA	NA	-3.89%
Vertex Pharmaceuticals Incorporated	BUY	$101.1B	47.85%	28.07	31.86%
Regeneron Pharmaceuticals, Inc.	BUY	$59.4B	-3.43%	14.11	31.37%

Stock Returns calculator for Orchestra Biomed Holdings Inc Stock including INR - Dollar returns

The Orchestra Biomed Holdings Inc stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.

Investment Value

₹1,00,000

Orchestra Biomed Holdings Inc investment value today

Current value as on today

₹49,315

Returns

₹50,685

(-50.68%)

Returns from Orchestra Biomed Holdings Inc Stock

₹55,670 (-55.67%)

Dollar Returns*

₹4,985 (+4.99%)

Analyst Recommendation on Orchestra Biomed Holdings Inc Stock

Based on 9 analysts

BUY

88.89%

Buy

11.11%

Hold

0.00%

Sell

Based on 9 analysts, 88.89% of analysts recommend a 'BUY' rating for Orchestra Biomed Holdings Inc. Average target price of $13.5

Orchestra Biomed Holdings Inc Share Price Target

Get share price movements and forecasts by analysts on Orchestra Biomed Holdings Inc.

What analysts predicted

80.89%UPSIDE

Target Price

$13.5

Current Price

$2.58

Analyzed by

9 Analysts

Target

$13.50

Orchestra Biomed Holdings Inc target price $13.5, a slight upside of 80.89% compared to current price of $2.58. According to 9 analysts rating.

Orchestra Biomed Holdings Inc Stock's Interest Amongst Investors

Search interest for Orchestra Biomed Holdings Inc Stock has increased by 67% in the last 30 days, reflecting an upward trend in search activity.

Time period: August 17, 2025 to September 16, 2025

Change:67% versus previous 30 day period

Orchestra Biomed Holdings Inc Quarterly Profit & Loss

All numbers in Millions USD

	Mar 2023	Jun 2023	Sep 2023	Dec 2023	Mar 2024	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025
Total Revenue	1	0	0	0	0	0	0	0	0	0
Gross Profit	1	0	0	0	0	0	0	0	0	0
Operating Income	-11	-12	-14	-12	-14	-16	-16	-16	-18	-19
EBITDA	-11	-12	-14	-12	-14	-16	-16	-16	-18	-19
Interest Expense	0	-	-	0	-	-	-	-	-	0
Depreciation	0	0	0	0	0	0	0	0	0	0
Income Before Tax	-10	-12	-13	-12	-13	-15	-15	-16	-18	-19
Income Tax Expense	0	0	-1	2	0	-	-	0	-	-
Net Income	-10	-12	-13	-12	-13	-15	-15	-16	-18	-19
Net Profit Margin	-939.86%	-1316.50%	-3178.04%	-4892.37%	-2171.45%	-2053.98%	-1562.92%	-6385.38%	-2160.71%	-2316.15%

Orchestra Biomed Holdings Inc Annual Profit & Loss

All numbers in Millions USD

	Dec 2020	Dec 2021	Dec 2022	Dec 2023	Dec 2024
Total Revenue	5	0	3	2	2
Gross Profit	5	0	3	2	2
Operating Income	-18	-21	-32	-51	-64
EBITDA	-18	-21	-32	-51	-64
Interest Expense	-	0	-	-	-
Depreciation	0	0	0	0	0
Income Before Tax	-21	-23	-33	-49	-61
Income Tax Expense	2	0	0	0	-
Net Income	-21	-23	-33	-49	-61
Net Profit Margin	-374.45%	2942.97%	-951.26%	-1779.71%	-2313.27%

Orchestra Biomed Holdings Inc Quarterly Cash Flow

All numbers in Millions USD

	Jun 2023	Sep 2023	Dec 2023	Mar 2024	Jun 2024	Sep 2024	Dec 2024	Mar 2025	Jun 2025
Net Income	-12	-13	-12	-13	-15	-15	-16	-18	-19
Operating Cash Flow	-10	-10	-10	-13	-10	-13	-13	-16	-15
Investing Cash Flow	8	12	33	5	10	0	-3	12	16
Financing Cash Flow	0	0	-10	0	0	15	13	0	0
Change in Cash	-2	2	11	-7	0	1	-3	-3	0

Orchestra Biomed Holdings Inc Annual Cash Flow

All numbers in Millions USD

	Dec 2021	Dec 2022	Dec 2023	Dec 2024
Net Income	-23	-33	-49	-61
Operating Cash Flow	-19	-29	-46	-50
Investing Cash Flow	13	-64	10	13
Financing Cash Flow	-3	103	46	29
Change in Cash	-10	9	10	-8

Insights on Orchestra Biomed Holdings Inc

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

NO EFFECT
Against Peers
In the last 1 year, Alnylam Pharmaceuticals, Inc. has given 70.6% return, outperforming this stock by 117.8%
NEGATIVE IMPACT
Price Dip
In the last 3 months, OBIO stock has moved down by -23.1%
NEGATIVE IMPACT
Profit Down
Netprofit is down for the last 4 quarters, -15.42M → -19.36M (in $), with an average decrease of 8.0% per quarter
NEGATIVE IMPACT
Revenue Fall
Revenue is down for the last 2 quarters, 868.0K → 836.0K (in $), with an average decrease of 3.7% per quarter

About Orchestra Biomed Holdings Inc

Orchestra BioMed Holdings, Inc. is a biomedical innovation company. The Company’s lead product candidates include Atrioventricular Interval Modulation (AVIM) therapy for the treatment of hypertension (HTN), the leading risk factor for death worldwide and the Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the leading cause of mortality worldwide. The Company develops bioelectronic therapies based on patented Cardiac Neuromodulation Therapy (CNT) technology. The AVIM is a bioelectronic therapy candidate designed to substantially and persistently lower blood pressure. Its Virtue SAB is a proprietary drug/device combination product candidate for the treatment of artery disease that is designed to deliver a proprietary, investigational, extended-release formulation of sirolimus (SirolimusEFR) to the vessel wall during balloon angioplasty without the need for balloon coating or a permanent implant.

Organisation	Orchestra Biomed Holdings Inc
Headquarters	150 Union Square Drive, New Hope, PA, United States, 18938
CEO	Mr. David P. Hochman
E-voting on shares	Click here to vote

Key Management of Orchestra Biomed Holdings Inc

Name	Title
Mr. Andrew Lawrence Taylor M.B.A.	Chief Financial Officer
Dr. Avraham Matityahu Fischer M.D.	Senior Vice President of Medical Affairs & Innovation
Mr. Bob Laughner	Senior Vice President of Regulatory & Quality
Mr. Juan Lorenzo	Senior Vice President of Product Development
Mr. Mark Pomeranz	GM & Executive VP of Interventional Therapies
Mr. David P. Hochman	Founder, Chairman of the Board of Directors & CEO
Mr. Darren R. Sherman	Founder, President, COO & Director
Mr. William Reed Little	Executive Vice President of Corporate Development & Strategy
Dr. Yuval Hay Mika D.Sc, Ph.D.	GM & CTO of Bioelectronic Therapies
Dr. Hans-Peter Stoll M.D., Ph.D.	Chief Clinical Officer

FAQs

What is Orchestra Biomed Holdings Inc share price today?

Orchestra Biomed Holdings Inc share price today is $2.58 as on September 16, 2025 at 1:29 am IST at the close of the market. Orchestra Biomed Holdings Inc share today touched a day high of $2.68 and a low of $2.54.

What is the 52 week high and 52 week low for Orchestra Biomed Holdings Inc share?

Orchestra Biomed Holdings Inc share touched a 52 week high of $6.5 on November 14, 2024 and a 52 week low of $2.37 on May 7, 2025. Orchestra Biomed Holdings Inc stock price today i.e. September 16, 2025 at 1:29 am IST is closed at $2.58,which is 60.31% down from its 52 week high and 8.86% up from its 52 week low.

What is Orchestra Biomed Holdings Inc's market capitalisation today?

Orchestra Biomed Holdings Inc market capitalisation is $0.00T as on September 16, 2025 at 1:29 am IST.

How to invest in Orchestra Biomed Holdings Inc Stock (OBIO) from India?

Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
Step 2: Search for Orchestra Biomed Holdings Inc on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Orchestra Biomed Holdings Inc Shares that will get you 0.5814 shares as per Orchestra Biomed Holdings Inc share price of $2.58 per share as on September 16, 2025 at 1:29 am IST.

What is the minimum amount required to buy Orchestra Biomed Holdings Inc Stock (OBIO) from India?

Indian investors can start investing in Orchestra Biomed Holdings Inc (OBIO) shares with as little as ₹88.141 or $1 (as of September 16, 2025 at 12:42 pm IST) using the INDmoney app.
For example: If you want to invest $10 or ₹881.41 in Orchestra Biomed Holdings Inc stock (as per the Rupee-Dollar exchange rate as on September 16, 2025 at 12:42 pm IST). Based on Orchestra Biomed Holdings Inc share’s latest price of $2.58 as on September 16, 2025 at 1:29 am IST, you will get 3.8760 shares of Orchestra Biomed Holdings Inc. Learn more about fractional shares .