Orchestra Biomed Holdings Inc share price logo

Orchestra Biomed Holdings Inc Share Price

NASDAQ: OBIO

Small Cap

$3.98

+0.18

(+4.74%)

as on

Orchestra Biomed Holdings Inc Stock Performance

as on October 25, 2025 at 1:29 am IST

  • Day's Low

    Day's High

    $3.71
    $4.04
    downward going graph

    6.78%

    Downside

    1.51%

    Upside

    downward going graph

  • 52 Week's Low

    52 Week's High

    $2.2
    $6.5
    downward going graph

    44.72%

    Downside

    63.32%

    Upside

    downward going graph

Orchestra Biomed Holdings Inc share price movements today

Previous Close
$3.80
Open
$3.80
Volume
542.7K
Day's Low - High
$3.71 - $4.04
52 Week Low - High
$2.2 - $6.5

Orchestra Biomed Holdings Inc Historical Returns

1 Month Return
+ 62.96 %
3 Month Return
+ 20.36 %
1 Year Return
-30.04 %
3 Year Return
0 %
5 Year Return
0 %

Orchestra Biomed Holdings Inc Stock Fundamentals & Key Indicators

Check Orchestra Biomed Holdings Inc market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$205.0M

EPS (TTM)

-1.8928

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.00%

PE Ratio (TTM)

0

PEG Ratio

0

EBITDA

-70.9M

Revenue (TTM)

2.9M

Profit Margin

0.00%

Return On Equity TTM

-313.82%

Orchestra Biomed Holdings Inc vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Orchestra Biomed Holdings Inc with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %
Orchestra Biomed Holdings Inc image
Orchestra Biomed Holdings Inc
BUY$205.0MNANA0.00%
Alnylam Pharmaceuticals, Inc. image
Alnylam Pharmaceuticals, Inc.
BUY$60.9B251.51%-505.15-12.96%
Beone Medicines Ltd image
Beone Medicines Ltd
NA$35.7BNANA-3.89%
Vertex Pharmaceuticals Incorporated image
Vertex Pharmaceuticals Incorporated
BUY$109.3B99.16%30.0431.86%
Regeneron Pharmaceuticals, Inc. image
Regeneron Pharmaceuticals, Inc.
BUY$62.0B-0.32%14.5131.37%

Stock Returns calculator for Orchestra Biomed Holdings Inc Stock including INR - Dollar returns

The Orchestra Biomed Holdings Inc stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.

Investment Value

₹1,00,000

  • 1Y

Orchestra Biomed Holdings Inc investment value today

Current value as on today

₹74,880

Returns

₹25,120

(-25.12%)

Returns from Orchestra Biomed Holdings Inc Stock

₹29,682 (-29.68%)

Dollar Returns*

₹4,562 (+4.56%)

Analyst Recommendation on Orchestra Biomed Holdings Inc Stock

Based on 9 analysts

BUY

88.89%

Buy

11.11%

Hold

0.00%

Sell

Based on 9 analysts, 88.89% of analysts recommend a 'BUY' rating for Orchestra Biomed Holdings Inc. Average target price of $13.5

Orchestra Biomed Holdings Inc Share Price Target

Get share price movements and forecasts by analysts on Orchestra Biomed Holdings Inc.

What analysts predicted

70.52%UPSIDE

Target Price

$13.5

Current Price

$3.98

Analyzed by

9 Analysts

Target

$13.50

Orchestra Biomed Holdings Inc target price $13.5, a slight upside of 70.52% compared to current price of $3.98. According to 9 analysts rating.

Orchestra Biomed Holdings Inc Stock’s Investor Sentiment and Interest

Search interest for Orchestra Biomed Holdings Inc Stock has decreased by -7% in the last 30 days, reflecting a downward trend in search activity.

Time period: to

Change:-7% versus previous 30 day period

Orchestra Biomed Holdings Inc Quarterly Profit & Loss

All numbers in Millions USD

Mar 2023
Jun 2023
Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Total Revenue
1
0
0
0
0
0
0
0
0
0
Gross Profit
1
0
0
0
0
0
0
0
0
0
Operating Income
-11
-12
-14
-12
-14
-16
-16
-16
-18
-19
EBITDA
-11
-12
-14
-12
-14
-16
-16
-16
-18
-19
Interest Expense
0
-
-
0
-
-
-
-
-
0
Depreciation
0
0
0
0
0
0
0
0
0
0
Income Before Tax
-10
-12
-13
-12
-13
-15
-15
-16
-18
-19
Income Tax Expense
0
0
-1
2
0
-
-
0
-
-
Net Income
-10
-12
-13
-12
-13
-15
-15
-16
-18
-19
Net Profit Margin
-939.86%
-1316.50%
-3178.04%
-4892.37%
-2171.45%
-2053.98%
-1562.92%
-6385.38%
-2160.71%
-2316.15%

Orchestra Biomed Holdings Inc Annual Profit & Loss

All numbers in Millions USD

Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Total Revenue
5
0
3
2
2
Gross Profit
5
0
3
2
2
Operating Income
-18
-21
-32
-51
-64
EBITDA
-18
-21
-32
-51
-64
Interest Expense
-
0
-
-
-
Depreciation
0
0
0
0
0
Income Before Tax
-21
-23
-33
-49
-61
Income Tax Expense
2
0
0
0
-
Net Income
-21
-23
-33
-49
-61
Net Profit Margin
-374.45%
2942.97%
-951.26%
-1779.71%
-2313.27%

Orchestra Biomed Holdings Inc Quarterly Cash Flow

All numbers in Millions USD

Jun 2023
Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Net Income
-12
-13
-12
-13
-15
-15
-16
-18
-19
Operating Cash Flow
-10
-10
-10
-13
-10
-13
-13
-16
-15
Investing Cash Flow
8
12
33
5
10
0
-3
12
16
Financing Cash Flow
0
0
-10
0
0
15
13
0
0
Change in Cash
-2
2
11
-7
0
1
-3
-3
0

Orchestra Biomed Holdings Inc Annual Cash Flow

All numbers in Millions USD

Dec 2021
Dec 2022
Dec 2023
Dec 2024
Net Income
-23
-33
-49
-61
Operating Cash Flow
-19
-29
-46
-50
Investing Cash Flow
13
-64
10
13
Financing Cash Flow
-3
103
46
29
Change in Cash
-10
9
10
-8

Insights on Orchestra Biomed Holdings Inc

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Price Rise

    img

    In the last 7 days, OBIO stock has moved up by 19.3%

  • imgNO EFFECT

    Against Peers

    img

    In the last 1 year, Alnylam Pharmaceuticals, Inc. has given 62.7% return, outperforming this stock by 92.7%

  • imgNEGATIVE IMPACT

    Profit Down

    img

    Netprofit is down for the last 4 quarters, -15.42M → -19.36M (in $), with an average decrease of 8.0% per quarter

  • imgNEGATIVE IMPACT

    Revenue Fall

    img

    Revenue is down for the last 2 quarters, 868.0K → 836.0K (in $), with an average decrease of 3.7% per quarter

About Orchestra Biomed Holdings Inc

Orchestra BioMed Holdings, Inc. is a biomedical innovation company. The Company’s lead product candidates include Atrioventricular Interval Modulation (AVIM) therapy for the treatment of hypertension (HTN), the leading risk factor for death worldwide and the Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the leading cause of mortality worldwide. The Company develops bioelectronic therapies based on patented Cardiac Neuromodulation Therapy (CNT) technology. The AVIM is a bioelectronic therapy candidate designed to substantially and persistently lower blood pressure. Its Virtue SAB is a proprietary drug/device combination product candidate for the treatment of artery disease that is designed to deliver a proprietary, investigational, extended-release formulation of sirolimus (SirolimusEFR) to the vessel wall during balloon angioplasty without the need for balloon coating or a permanent implant.
OrganisationOrchestra Biomed Holdings Inc
Headquarters150 Union Square Drive, New Hope, PA, United States, 18938
CEOMr. David P. Hochman
E-voting on sharesClick here to vote

Key Management of Orchestra Biomed Holdings Inc

Name

Title

Mr. Darren R. Sherman

Founder, President, COO & Director

Mr. Andrew Lawrence Taylor M.B.A.

Chief Financial Officer

Dr. Yuval Hay Mika D.Sc, Ph.D.

GM & CTO of Bioelectronic Therapies

Dr. Avraham Matityahu Fischer M.D.

Senior Vice President of Medical Affairs & Innovation

Mr. Bob Laughner

Senior Vice President of Regulatory & Quality

Mr. Juan Lorenzo

Senior Vice President of Product Development

Mr. Mark Pomeranz

GM & Executive VP of Interventional Therapies

Mr. David P. Hochman

Founder, Chairman of the Board of Directors & CEO

Mr. William Reed Little

Executive Vice President of Corporate Development & Strategy

Dr. Hans-Peter Stoll M.D., Ph.D.

Chief Clinical Officer

FAQs

What is Orchestra Biomed Holdings Inc share price today?

Orchestra Biomed Holdings Inc share price today is $3.98 as on at the close of the market. Orchestra Biomed Holdings Inc share today touched a day high of $4.04 and a low of $3.71.

What is the 52 week high and 52 week low for Orchestra Biomed Holdings Inc share?

Orchestra Biomed Holdings Inc share touched a 52 week high of $6.5 on and a 52 week low of $2.2 on . Orchestra Biomed Holdings Inc stock price today i.e. is closed at $3.98,which is 38.77% down from its 52 week high and 80.91% up from its 52 week low.

What is Orchestra Biomed Holdings Inc's market capitalisation today?

Orchestra Biomed Holdings Inc market capitalisation is $0.00T as on .

How to invest in Orchestra Biomed Holdings Inc Stock (OBIO) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Orchestra Biomed Holdings Inc on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Orchestra Biomed Holdings Inc Shares that will get you 0.3769 shares as per Orchestra Biomed Holdings Inc share price of $3.98 per share as on October 25, 2025 at 1:29 am IST.

What is the minimum amount required to buy Orchestra Biomed Holdings Inc Stock (OBIO) from India?

Indian investors can start investing in Orchestra Biomed Holdings Inc (OBIO) shares with as little as ₹87.759 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹877.59 in Orchestra Biomed Holdings Inc stock (as per the Rupee-Dollar exchange rate as on ). Based on Orchestra Biomed Holdings Inc share’s latest price of $3.98 as on October 25, 2025 at 1:29 am IST, you will get 2.5126 shares of Orchestra Biomed Holdings Inc. Learn more about fractional shares .