Lexicon Pharmaceuticals, Inc. share price logo

Lexicon Pharmaceuticals, Inc. Share Price

NASDAQ: LXRX

Small Cap

$1.63

+0.07

(+4.49%)

as on

Lexicon Pharmaceuticals, Inc. Stock Performance

as on March 24, 2026 at 6:59 am IST

  • Day's Low

    Day's High

    $1.55
    $1.66
    downward going graph

    4.91%

    Downside

    1.84%

    Upside

    downward going graph

  • 52 Week's Low

    52 Week's High

    $0.32
    $1.83
    downward going graph

    80.37%

    Downside

    12.27%

    Upside

    downward going graph

Lexicon Pharmaceuticals, Inc. share price movements today

Previous Close
$1.56
Open
$1.57
Volume
2.2M
Day's Low - High
$1.55 - $1.66
52 Week Low - High
$0.32 - $1.83

Lexicon Pharmaceuticals, Inc. Historical Returns

1 Month Return
+ 3.31 %
3 Month Return
+ 28.93 %
1 Year Return
+ 329.52 %
3 Year Return
-30.97 %
5 Year Return
-74.8 %

Lexicon Pharmaceuticals, Inc. Stock Fundamentals & Key Indicators

Check Lexicon Pharmaceuticals, Inc. market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$660.9M

EPS (TTM)

-0.1811

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

-0.63%

PE Ratio (TTM)

-3.22

Industry PE ratio

-4.738881355932204

PEG Ratio

-0.14

EBITDA

-48.3M

Revenue (TTM)

49.8M

Profit Margin

-101.08%

Return On Equity TTM

-39.72%

Lexicon Pharmaceuticals, Inc. Stock Valuation

Track how Lexicon Pharmaceuticals, Inc. P/E has moved over time to understand its valuation trends.

Lexicon Pharmaceuticals, Inc. in the last 5 years

  • Overview

  • Trends

Lowest (-57.70x)

March 31, 2021

Industry (-4.74x)

March 23, 2026

Today (-3.22x)

March 23, 2026

Highest (12.67x)

June 30, 2021

LowHigh

Today’s Price to Earnings Ratio: -3.22x

Lexicon Pharmaceuticals, Inc. vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Lexicon Pharmaceuticals, Inc. with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %
Lexicon Pharmaceuticals, Inc. image
Lexicon Pharmaceuticals, Inc.
BUY$660.9M-74.8%-3.22-101.08%
Alnylam Pharmaceuticals, Inc. image
Alnylam Pharmaceuticals, Inc.
BUY$41.4B125.13%133.418.45%
Vertex Pharmaceuticals Incorporated image
Vertex Pharmaceuticals Incorporated
BUY$115.3B112.56%29.6732.94%
Beone Medicines Ltd image
Beone Medicines Ltd
NA$31.6BNA1115.37%
Regeneron Pharmaceuticals, Inc. image
Regeneron Pharmaceuticals, Inc.
BUY$77.5B56.01%17.6731.41%

Stock Returns calculator for Lexicon Pharmaceuticals, Inc. Stock including INR - Dollar returns

The Lexicon Pharmaceuticals, Inc. stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.

Investment Value

₹1,00,000

  • 1Y

  • 3Y

  • 5Y

  • 7Y

  • 10Y

Lexicon Pharmaceuticals, Inc. investment value today

Current value as on today

₹4,62,697

Returns

₹3,62,697

(+362.7%)

Returns from Lexicon Pharmaceuticals, Inc. Stock

₹3,52,778 (+352.78%)

Dollar Returns*

₹9,919 (+9.92%)

Analyst Recommendation on Lexicon Pharmaceuticals, Inc. Stock

Based on 11 analysts

BUY

72.73%

Buy

27.27%

Hold

0.00%

Sell

Based on 11 analysts, 72.73% of analysts recommend a 'BUY' rating for Lexicon Pharmaceuticals, Inc.. Average target price of $3.36

Lexicon Pharmaceuticals, Inc. Share Price Target

Get share price movements and forecasts by analysts on Lexicon Pharmaceuticals, Inc..

What analysts predicted

51.49%UPSIDE

Target Price

$3.36

Current Price

$1.63

Analyzed by

11 Analysts

Target

$3.36

Lexicon Pharmaceuticals, Inc. target price $3.36, a slight upside of 51.49% compared to current price of $1.63. According to 11 analysts rating.

Lexicon Pharmaceuticals, Inc. Stock’s Investor Sentiment and Interest

Search interest for Lexicon Pharmaceuticals, Inc. Stock has decreased by -58% in the last 30 days, reflecting a downward trend in search activity.

Time period: to

Change:-58% versus previous 30 day period

Lexicon Pharmaceuticals, Inc. Quarterly Profit & Loss

All numbers in Millions USD

Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Total Revenue
0
0
1
1
1
26
1
28
14
5
Gross Profit
0
-14
0
1
1
0
1
28
14
5
Operating Income
-49
-46
-45
-55
-63
-32
-25
3
-12
-14
EBITDA
-46
-45
-44
-51
-60
-20
-23
5
-10
-14
Interest Expense
3
5
4
2
4
3
1
2
2
2
Depreciation
0
0
0
0
0
0
0
0
0
0
Income Before Tax
-50
-49
-48
-53
-64
-33
-25
3
-12
-15
Income Tax Expense
2
-2
0
-
-
0
-
-
-
-
Net Income
-50
-49
-48
-53
-64
-33
-25
3
-12
-15
Net Profit Margin
-31188.27%
-7087.75%
-4282.92%
-3244.02%
-3703.49%
-127.16%
-2004.36%
11.27%
-90.04%
-282.72%

Lexicon Pharmaceuticals, Inc. Annual Profit & Loss

All numbers in Millions USD

Dec 2016
Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Total Revenue
83
90
63
322
23
0
0
1
31
49
Gross Profit
-80
88
60
318
22
-54
-52
-57
30
49
Operating Income
-137
-136
-103
141
-47
-87
-100
-171
-197
-48
EBITDA
-125
-125
-96
148
-41
-86
-100
-169
-184
-48
Interest Expense
6
6
20
20
14
0
2
13
15
8
Depreciation
-
3
3
3
2
0
0
0
0
0
Income Before Tax
-141
-141
-120
124
-58
-87
-101
-177
-200
-50
Income Tax Expense
4
-12
3
-6
11
0
1
0
-200
-
Net Income
-141
-129
-120
130
-58
-87
-101
-177
-200
-50
Net Profit Margin
-169.71%
-142.86%
-190.71%
40.40%
-244.11%
-29448.99%
-73341.01%
-14710.88%
-644.78%
-101.08%

Lexicon Pharmaceuticals, Inc. Quarterly Cash Flow

All numbers in Millions USD

Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Net Income
-49
-48
-53
-64
-33
-25
3
-12
-15
Operating Cash Flow
-50
-55
-48
-53
-21
-43
16
-23
-17
Investing Cash Flow
51
-110
-12
53
53
40
15
52
4
Financing Cash Flow
0
239
0
0
0
0
-45
-
-2
Change in Cash
1
74
-60
-1
32
-3
-12
28
-15

Lexicon Pharmaceuticals, Inc. Annual Cash Flow

All numbers in Millions USD

Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Net Income
-129
-120
130
-58
-87
-101
-177
-200
-50
Operating Cash Flow
-185
-148
113
-142
-87
-88
-161
-178
-67
Investing Cash Flow
50
169
-155
380
2
-71
-49
-15
113
Financing Cash Flow
149
-2
-2
-147
22
142
187
238
-48
Change in Cash
15
18
-44
90
-62
-17
-23
44
-3

Global Institutional Holdings in Lexicon Pharmaceuticals, Inc.

Funds
Holdings
BlackRock Inc
0.81%
HRT FINANCIAL LLC
0.13%
Sessa Capital IM LP
0.83%
Citadel Advisors Llc
0.41%
Ishara Investments LP
0.21%
See all

Insights on Lexicon Pharmaceuticals, Inc.

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Best in 1 Year

    img

    In the last 1 year, LXRX has outperformed top 5 stocks with highest market-cap in its industry

  • imgPOSITIVE IMPACT

    Price Rise

    img

    In the last 3 months, LXRX stock has moved up by 28.9%

  • imgNO EFFECT

    Against Peers

    img

    In the last 3 years, Lexicon Pharmaceuticals, Inc. has experienced a drawdown of -31.0%, however Alnylam Pharmaceuticals, Inc. resisted the overall trend and outperformed by 22.4%

  • imgNEGATIVE IMPACT

    Revenue Fall

    img

    Revenue is down for the last 3 quarters, 28.86M → 5.49M (in $), with an average decrease of 56.1% per quarter

  • imgNEGATIVE IMPACT

    Profit Down

    img

    Netprofit is down for the last 3 quarters, 3.25M → -15.53M (in $), with an average decrease of 257.1% per quarter

About Lexicon Pharmaceuticals, Inc.

corporate overview lexicon pharmaceuticals is a biopharmaceutical company that has harnessed the power of genetics for drug discovery. our research team has generated a pipeline of novel drug candidates in clinical development across a broad range of indications. the genome: our source of discovery we have applied gene knockout technology to thousands of potential drug targets encoded in the human genome. our scientists have gained a thorough understanding of target biology and identified new points of intervention for future therapies. we have integrated a series of recombinant dna and chemistry technologies into a systematic drug discovery and development process. our unique knowledge of targets from the human genome has allowed us to better evaluate and advance novel drug candidates with great promise for patients. a diverse pipeline of targeted therapies our genomics-based approach to drug discovery has enabled our scientists to select drug targets across a broad range of indicatio
OrganisationLexicon Pharmaceuticals, Inc.
Headquarters2445 Technology Forest Boulevard, The Woodlands, TX, United States, 77381
IndustryHealth Technology
CEODr. Michael S. Exton Ph.D.
E-voting on sharesClick here to vote

Key Management of Lexicon Pharmaceuticals, Inc.

Name

Title

Dr. Michael S. Exton Ph.D.

CEO & Director

Mr. Scott M. Coiante

Senior VP & CFO

Dr. Craig B. Granowitz M.D., Ph.D.

Senior VP & Chief Medical Officer

Ms. Rachel Yap Martens

Senior VP of Partnerships & Corporate Strategy

Dr. Suma Gopinathan M.S., Ph.D.

Senior Vice President of Discovery

Mr. Brian T. Crum

Senior VP, General Counsel & Secretary

Ms. Wendy E. McDermott

Senior Vice President of Human Resources

Ms. Kristen L. Alexander

Vice President of Finance & Accounting

Ms. Lisa M. DeFrancesco

Senior Vice President of Investor Relations & Corporate Communications

FAQs

What is Lexicon Pharmaceuticals, Inc. share price today?

Lexicon Pharmaceuticals, Inc. share price today is $1.63 as on at the close of the market. Lexicon Pharmaceuticals, Inc. share today touched a day high of $1.66 and a low of $1.55.

What is the 52 week high and 52 week low for Lexicon Pharmaceuticals, Inc. share?

Lexicon Pharmaceuticals, Inc. share touched a 52 week high of $1.83 on and a 52 week low of $0.32 on . Lexicon Pharmaceuticals, Inc. stock price today i.e. is closed at $1.63,which is 10.93% down from its 52 week high and 409.37% up from its 52 week low.

What is Lexicon Pharmaceuticals, Inc.'s market capitalisation today?

Lexicon Pharmaceuticals, Inc. market capitalisation is $0.00T as on .

How to invest in Lexicon Pharmaceuticals, Inc. Stock (LXRX) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Lexicon Pharmaceuticals, Inc. on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Lexicon Pharmaceuticals, Inc. Shares that will get you 0.9202 shares as per Lexicon Pharmaceuticals, Inc. share price of $1.63 per share as on March 24, 2026 at 1:29 am IST.

What is the minimum amount required to buy Lexicon Pharmaceuticals, Inc. Stock (LXRX) from India?

Indian investors can start investing in Lexicon Pharmaceuticals, Inc. (LXRX) shares with as little as ₹94.058 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹940.58 in Lexicon Pharmaceuticals, Inc. stock (as per the Rupee-Dollar exchange rate as on ). Based on Lexicon Pharmaceuticals, Inc. share’s latest price of $1.63 as on March 24, 2026 at 1:29 am IST, you will get 6.1350 shares of Lexicon Pharmaceuticals, Inc.. Learn more about fractional shares .

What are the returns that Lexicon Pharmaceuticals, Inc. has given to Indian investors in the last 5 years?

Lexicon Pharmaceuticals, Inc. stock has given -74.8% share price returns and 29.13% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?