Denali Therapeutics logo

Denali Therapeutics Share Price (NASDAQ: DNLI)

$15.5

0.27

(1.77%)

Last updated on

Check the interactive Denali Therapeutics Stock chart to analyse performance

Denali Therapeutics stock performance

as on August 23, 2025 at 1:29 AM IST

  • Today's Low:$15.39
    Today's High:$16.10

    Day's Volatility :4.41%

  • 52 Weeks Low:$10.57
    52 Weeks High:$33.33

    52 Weeks Volatility :68.29%

Denali Therapeutics Stock Returns

PeriodDenali Therapeutics IncSector (Health Care)Index (Russel 2000)
3 Months
17.26%
5.1%
0.0%
6 Months
-25.06%
-6.4%
0.0%
1 Year
-37.46%
-11.8%
0.0%
3 Years
-50.05%
5.9%
-7.8%

Denali Therapeutics Inc Key Stats

Check Denali Therapeutics key stats like market cap, P/E ratio, EPS, Dividend Yield, and more.

Previous Close
$15.23
Open
$15.47
Today's High
$16.1
Today's Low
$15.39
Market Capitalization
$2.2B
Today's Volume
$2.7M
52 Week High
$33.33
52 Week Low
$10.57
Revenue TTM
$0.0
EBITDA
$-529.4M
Earnings Per Share (EPS)
$-2.81
Profit Margin
0.0%
Quarterly Earnings Growth YOY
0.0%
Return On Equity TTM
-39.69%

Stock Returns calculator for Denali Therapeutics Stock including INR - Dollar returns

The Denali Therapeutics stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.

Investment Value

₹1,00,000

  • 1Y

  • 3Y

  • 5Y

  • 7Y

  • 10Y

Denali Therapeutics investment value today

Current value as on today

₹66,892

Returns

₹33,108

(-33.11%)

Returns from Denali Therapeutics Stock

₹37,424 (-37.42%)

Dollar Returns*

₹4,316 (+4.32%)

Indian investors sentiment towards Denali Therapeutics Stock

27%

Period: Jul 23, 2025 to Aug 22, 2025. Change in 30 Days versus previous period

Search interest for Denali Therapeutics Stock from India on INDmoney has increased by 27% in the last 30 days, reflecting an upward trend in search activity.

Global Institutional Holdings in Denali Therapeutics Inc

  • Name

    Holdings %

  • BlackRock Inc

    9.50%

  • Baillie Gifford & Co Limited.

    8.21%

  • Vanguard Group Inc

    8.11%

  • FMR Inc

    5.09%

  • T. Rowe Price Associates, Inc.

    4.52%

  • UBS Asset Mgmt Americas Inc

    4.30%

Analyst Recommendation on Denali Therapeutics Stock

Rating
Trend

Buy

    86%Buy

    13%Hold

    0%Sell

Based on 23 Wall street analysts offering stock ratings for Denali Therapeutics(by analysts ranked 0 to 5 stars)

Denali Therapeutics Share Price Target

What analysts predicted

Upside of 103.23%

Target:

$31.50

Current:

$15.50

Denali Therapeutics share price target is $31.50, a slight Upside of 103.23% compared to current price of $15.50 as per analysts' prediction.

Denali Therapeutics Stock Insights

  • Price Movement

    In the last 7 days, DNLI stock has moved up by 3.6%
  • Decreasing Revenue

    Revenue is down for the last 3 quarters, 294.12M → -305.04M (in $), with an average decrease of 12137.8% per quarter
  • Increasing Net Profit

    Netprofit is up for the last 2 quarters, -132.97M → -124.11M (in $), with an average increase of 7.1% per quarter
  • DNLI vs ALNY (1 yr)

    In the last 1 year, Alnylam Pharmaceuticals, Inc. has given 71.2% return, outperforming this stock by 109.7%
  • DNLI vs ALNY (3 yr)

    In the last 3 years, Alnylam Pharmaceuticals, Inc. has given 115.2% return, outperforming this stock by 167.6%

Denali Therapeutics Technicals Summary

Sell

Neutral

Buy

Denali Therapeutics is currently in a favorable trading position ( BUY ) according to technical analysis indicators.

Denali Therapeutics Inc Vs Peers

Returns
Ratio's
Overview
Company Name1 Month6 Month1 Year3 Years5 Years
Denali Therapeutics Inc logo
6.46%
-25.06%
-37.46%
-50.05%
-53.62%
Regeneron Pharmaceuticals, Inc. logo
5.93%
-17.37%
-50.85%
-2.23%
-0.91%
Beone Medicines Ltd logo
5.81%
21.35%
61.84%
78.01%
32.14%
Vertex Pharmaceuticals Incorporated logo
-15.86%
-17.97%
-17.9%
35.76%
47.74%
Alnylam Pharmaceuticals, Inc. logo
42.31%
82.49%
66.63%
105.56%
244.81%

Denali Therapeutics Dividend announcements

  • Denali Therapeutics Earnings

    Denali Therapeutics’s price-to-earnings ratio stands at None

About Denali Therapeutics Inc

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; DNL343 eIF2B activator program for amyotrophic lateral sclerosis; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson's and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company's OTV programs also comprise DNL628 targeting tau for Alzheimer's disease; and DNL422 targeting alpha synuclein for Parkinson's disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer's disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.
Organization
Denali Therapeutics
Employees
486
CEO
Dr. Ryan J. Watts Ph.D.
Industry
Health Technology

Key Management of Denali Therapeutics Inc

NameTitle
Dr. Ryan J. Watts Ph.D.
Co-Founder, President, CEO & Director
Dr. Alexander O. Schuth M.D.
Co-Founder, CFO, COO & Secretary
Dr. Marc Tessier-Lavigne Ph.D.
Co-Founder & Independent Director
Dr. Carole Ho M.D.
Chief Medical Officer & Head of Development
Dr. Dana Andersen
Chief Technical and Manufacturing Officer
Mr. Joe Lewcock Ph.D.
Chief Scientific Officer
Mr. Chris Walsh J.D.
General Counsel
Ms. Cindy Dunkle
Chief People Officer
Ms. Katie Peng
Chief Commercial Officer

Important FAQs about investing in DNLI Stock from India :

What is Denali Therapeutics share price today?

Denali Therapeutics share price today is $15.50 as on at the close of the market. Denali Therapeutics share today touched a day high of $16.10 and a low of $15.39.

What is the 52 week high and 52 week low for Denali Therapeutics share?

Denali Therapeutics share touched a 52 week high of $33.33 and a 52 week low of $10.57. Denali Therapeutics stock price today i.e. is closed at $15.50, lower by 53.5% versus the 52 week high.

How to invest in Denali Therapeutics Stock (DNLI) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Denali Therapeutics on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Denali Therapeutics Shares that will get you 0.0968 shares as per Denali Therapeutics share price of $15.50 per share as on August 23, 2025 at 1:29 AM IST.

What is the minimum amount required to buy Denali Therapeutics Stock (DNLI) from India?

Indian investors can start investing in Denali Therapeutics (DNLI) shares with as little as ₹87.521 or $1 (as of August 23, 2025) using the INDmoney app.
For example: If you want to invest $10 or ₹875.21 in Denali Therapeutics stock (as per the Rupee-Dollar exchange rate as on August 23, 2025). Based on Denali Therapeutics share’s latest price of $15.50 as on August 23, 2025 at 1:29 AM IST, you will get 0.6452 shares of Denali Therapeutics. Learn more about fractional shares .

What are the returns that Denali Therapeutics has given to Indian investors in the last 5 years?

Denali Therapeutics stock has given -53.62% share price returns and 18.0% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your US Stock Investments?