as on November 1, 2025 at 1:29 am IST
Day's Low
Day's High

2.34%
Downside
0.29%
Upside

52 Week's Low
52 Week's High

14.85%
Downside
22.11%
Upside

Check Vertex Pharmaceuticals Incorporated market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.
Market Cap
$107.0B
EPS (TTM)
18.0142
Dividend Yield
0.00%
Quarterly Earnings Growth YOY
-0.41%
PE Ratio (TTM)
29.67
Industry PE ratio
19.200384615384614
PEG Ratio
0.5801
EBITDA
4.6B
Revenue (TTM)
11.4B
Profit Margin
31.86%
Return On Equity TTM
22.77%
Track how Vertex Pharmaceuticals Incorporated P/E has moved over time to understand its valuation trends.
Vertex Pharmaceuticals Incorporated in the last 5 years
Lowest (14.94x)
December 31, 2021
Industry (19.20x)
October 31, 2025
Today (29.67x)
October 31, 2025
Highest (34.74x)
September 30, 2025
Today’s Price to Earnings Ratio: 29.67x
Compare market cap, revenue, PE, and other key metrics of Vertex Pharmaceuticals Incorporated with its industry peers.
| Company | Analyst View | Market Cap | 5 Years Return % | PE Ratio | Profit Margin % | 
|---|---|---|---|---|---|
| BUY | $107.0B | 101.52% | 29.67 | 31.86% | |
| BUY | $41.1B | 489.62% | -16.34 | -259.82% | |
| BUY | $63.1B | 265.59% | -505.15 | -12.96% | |
| BUY | $68.6B | 20.33% | 15.65 | 32.13% | 
The Vertex Pharmaceuticals Incorporated stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.
*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.
Investment Value
₹1,00,000
Vertex Pharmaceuticals Incorporated investment value today
Current value as on today
₹95,084
Returns
Returns from Vertex Pharmaceuticals Incorporated Stock
Dollar Returns*
₹5,642 (+5.64%)
Based on 38 analysts
68.42%
Buy
26.32%
Hold
5.26%
Sell
Based on 38 analysts, 68.42% of analysts recommend a 'BUY' rating for Vertex Pharmaceuticals Incorporated. Average target price of $480.84
Get share price movements and forecasts by analysts on Vertex Pharmaceuticals Incorporated.
What analysts predicted
11.46%UPSIDE
Target Price
$480.84
Current Price
$425.73
Analyzed by
38 Analysts
Target
$480.84
Vertex Pharmaceuticals Incorporated target price $480.84, a slight upside of 11.46% compared to current price of $425.73. According to 38 analysts rating.
Investment in Vertex Pharmaceuticals Incorporated Shares on INDmoney has grown by 4.21% over the past 30 days, indicating increased transactional activity.
Time period: to
Change:4.21% versus previous 30 day period
Search interest for Vertex Pharmaceuticals Incorporated Stock has increased by 30% in the last 30 days, reflecting an upward trend in search activity.
Time period: to
Change:30% versus previous 30 day period
All numbers in Millions USD
All numbers in Millions USD
All numbers in Millions USD
All numbers in Millions USD

Today's Timeline - 29 October
Wed, 06:45 PM
-Vertex Pharmaceuticals expected to report Q3 earnings of $4.55 per share, with revenue forecasted at $3.04 billion.
Wed, 08:57 PM
-Vertex Pharmaceuticals has a Zacks Rank #3 and an Earnings ESP of +0.57%.
Thu, 03:20 AM
-Vertex Pharmaceuticals closed at $417.21, down 1.23%, with upcoming earnings announcement on November 3, 2025.
Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.
 POSITIVE IMPACT
POSITIVE IMPACTRevenue Rich

Vertex Pharmaceuticals Incorporated has shown a positive revenue trend over the last two quarters. In the most recent quarter, the revenue increased to $2.96 billion, up from $2.77 billion in the previous quarter. This represents an average increase of 6.6% in revenue each quarter.
 POSITIVE IMPACT
POSITIVE IMPACTProfit Spike

Vertex Pharmaceuticals Incorporated has shown a positive trend in its net profit over the last two quarters. The net profit increased from $646.3 million to $1.03 billion, reflecting an average increase of 37.4% per quarter.
 POSITIVE IMPACT
POSITIVE IMPACTPrice Rise

In the last 1 month, VRTX stock has moved up by 7.2%
 NO EFFECT
NO EFFECTAgainst Peers

In the last 1 year, Insmed Incorporated has given 188.7% return, outperforming this stock by 200.5%
 NO EFFECT
NO EFFECTAgainst Peers

In the last 3 years, Insmed Incorporated has given 1021.4% return, outperforming this stock by 986.8%
| Organisation | Vertex Pharmaceuticals Incorporated | 
| Headquarters | 50 Northern Avenue, Boston, MA, United States, 02210 | 
| Industry | Health Technology | 
| CEO | Dr. Reshma Kewalramani FASN, M.D. | 
| E-voting on shares | Click here to vote | 
| Name | Title | 
|---|---|
| Ms. Susie Lisa C.F.A. | Senior Vice President of Investor Relations | 
| Dr. Jeffrey Marc Leiden M.D., Ph.D. | Executive Chairman | 
| Dr. Ourania Tatsis Ph.D. | Executive VP and Chief Regulatory & Quality Officer | 
| Ms. Kristen C. Ambrose CPA | Senior VP & Chief Accounting Officer | 
| Mr. Jonathan Biller J.D. | Executive VP & Chief Legal Officer | 
| Ms. Nina Devlin | Senior VP & Chief Communications Officer | 
| Ms. Stephanie Franklin | Senior VP & Chief Human Resources Officer | 
| Dr. Reshma Kewalramani FASN, M.D. | CEO, President & Director | 
| Mr. Charles F. Wagner Jr. | Executive VP, COO & CFO | 
| Dr. David M. Altshuler M.D., Ph.D. | Executive VP & Chief Scientific Officer | 
Vertex Pharmaceuticals Incorporated share price today is $425.73 as on at the close of the market. Vertex Pharmaceuticals Incorporated share today touched a day high of $426.96 and a low of $415.76.
Vertex Pharmaceuticals Incorporated share touched a 52 week high of $519.88 on and a 52 week low of $362.5 on . Vertex Pharmaceuticals Incorporated stock price today i.e. is closed at $425.73,which is 18.11% down from its 52 week high and 17.44% up from its 52 week low.
Vertex Pharmaceuticals Incorporated market capitalisation is $0.11T as on .
Indian investors can start investing in Vertex Pharmaceuticals Incorporated (VRTX) shares with as little as ₹88.665 or $1 (as of ) using the INDmoney app. 
      
      For example: If you want to invest $10 or ₹886.65 in Vertex Pharmaceuticals Incorporated stock (as per the Rupee-Dollar exchange rate as on ). 
        Based on Vertex Pharmaceuticals Incorporated share’s latest price of $425.73 as on November 1, 2025 at 1:29 am IST, you will get 0.0235 shares of Vertex Pharmaceuticals Incorporated. Learn more about
          
            fractional shares .
        
Vertex Pharmaceuticals Incorporated stock has given 101.52% share price returns and 21.02% dollar appreciation to an Indian investor in the last 5 years.
        
 Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?