Vertex Pharmaceuticals Incorporated Stock Performance
as on December 13, 2025 at 2:29 am IST
Day's Low
Day's High
$444.98$456
1.60%
Downside
0.83%
Upside
52 Week's Low
52 Week's High
$362.5$519.6819.84%
Downside
14.91%
Upside
Vertex Pharmaceuticals Incorporated share price movements today
- Previous Close
- $445.93
- Open
- $444.98
- Volume
- 1.3M
- Day's Low - High
- $444.98 - $456
- 52 Week Low - High
- $362.5 - $519.68
Vertex Pharmaceuticals Incorporated Historical Returns
- 1 Month Return
- + 3.41 %
- 3 Month Return
- + 14.96 %
- 1 Year Return
- -2.52 %
- 3 Year Return
- + 46.58 %
- 5 Year Return
- + 97.56 %
Vertex Pharmaceuticals Incorporated Stock Fundamentals & Key Indicators
Check Vertex Pharmaceuticals Incorporated market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.
Market Cap
$115.9B
EPS (TTM)
18.4486
Dividend Yield
0.00%
Quarterly Earnings Growth YOY
0.05%
PE Ratio (TTM)
31.86
Industry PE ratio
19.200384615384614
PEG Ratio
0.5801
EBITDA
4.7B
Revenue (TTM)
11.7B
Profit Margin
31.35%
Return On Equity TTM
22.31%
Vertex Pharmaceuticals Incorporated Stock Valuation
Track how Vertex Pharmaceuticals Incorporated P/E has moved over time to understand its valuation trends.
Vertex Pharmaceuticals Incorporated in the last 5 years
Lowest (14.94x)
December 31, 2021
Industry (19.20x)
December 15, 2025
Today (31.86x)
December 15, 2025
Highest (34.74x)
September 30, 2025
Today’s Price to Earnings Ratio: 31.86x
Vertex Pharmaceuticals Incorporated vs Peer Comparison
Compare market cap, revenue, PE, and other key metrics of Vertex Pharmaceuticals Incorporated with its industry peers.
Company | Analyst View | Market Cap | 5 Years Return % | PE Ratio | Profit Margin % |
|---|---|---|---|---|---|
| BUY | $115.9B | 97.56% | 31.86 | 31.35% | |
| BUY | $42.0B | 385.96% | -16.34 | -264.83% | |
| BUY | $52.5B | 192.96% | 1242.34 | 1.36% | |
| BUY | $78.6B | 50.73% | 17.76 | 32.13% |
Stock Returns calculator for Vertex Pharmaceuticals Incorporated Stock including INR - Dollar returns
The Vertex Pharmaceuticals Incorporated stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.
*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.
Investment Value
₹1,00,000
Vertex Pharmaceuticals Incorporated investment value today
Current value as on today
₹1,04,146
Returns
₹4,146
(+4.15%)
Returns from Vertex Pharmaceuticals Incorporated Stock
Dollar Returns*
₹6,626 (+6.63%)
Analyst Recommendation on Vertex Pharmaceuticals Incorporated Stock
Based on 38 analysts
68.42%
Buy
26.32%
Hold
5.26%
Sell
Based on 38 analysts, 68.42% of analysts recommend a 'BUY' rating for Vertex Pharmaceuticals Incorporated. Average target price of $489.48
Vertex Pharmaceuticals Incorporated Share Price Target
Get share price movements and forecasts by analysts on Vertex Pharmaceuticals Incorporated.
What analysts predicted
7.61%UPSIDE
Target Price
$489.48
Current Price
$452.23
Analyzed by
38 Analysts
Target
$489.48
Vertex Pharmaceuticals Incorporated target price $489.48, a slight upside of 7.61% compared to current price of $452.23. According to 38 analysts rating.
Vertex Pharmaceuticals Incorporated Stock’s Investor Sentiment and Interest
Investment in Vertex Pharmaceuticals Incorporated Shares on INDmoney has grown by 15.38% over the past 30 days, indicating increased transactional activity.
Time period: to
Change:15.38% versus previous 30 day period
Search interest for Vertex Pharmaceuticals Incorporated Stock has increased by 31% in the last 30 days, reflecting an upward trend in search activity.
Time period: to
Change:31% versus previous 30 day period
Vertex Pharmaceuticals Incorporated Quarterly Profit & Loss
All numbers in Millions USD
Vertex Pharmaceuticals Incorporated Annual Profit & Loss
All numbers in Millions USD
Vertex Pharmaceuticals Incorporated Quarterly Cash Flow
All numbers in Millions USD
Vertex Pharmaceuticals Incorporated Annual Cash Flow
All numbers in Millions USD
Mutual Funds that own Vertex Pharmaceuticals Incorporated Stock
Check out the Mutual Funds with significant holdings in Vertex Pharmaceuticals Incorporated.
Funds | Holdings | Shares Held |
|---|---|---|
 Motilal Oswal S&P 500 Index Fund Direct Growth | 0.18881% | 1998 |
 ICICI Prudential NASDAQ 100 Index Fund Direct Growth | 0.57821% | 3908 |
 Edelweiss MSCI India Domestic & World Healthcare 45 Index Fund Direct Growth | 0.87937% | 398 |
Global Institutional Holdings in Vertex Pharmaceuticals Incorporated
Vertex Pharmaceuticals Incorporated News & Key Events
Today's Timeline - 03 December
Thu, 00:41 AM
-Vertex Pharmaceuticals shares rise 6.2% after Morgan Stanley upgrades rating to Overweight and raises price target to $516.
Insights on Vertex Pharmaceuticals Incorporated
Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.
POSITIVE IMPACTRevenue Rich
Vertex Pharmaceuticals Incorporated has shown consistent growth in its quarterly revenue over the last three quarters. Revenue increased from $2.77 billion to $3.07 billion, reflecting an average growth rate of 5.1% per quarter.
- POSITIVE IMPACT
Profit Spike
Vertex Pharmaceuticals has shown positive profit trends over the last three quarters. The company's net profit has increased from $646.3 million to $1.08 billion, representing an average growth of 21.0% per quarter.
- POSITIVE IMPACT
Price Rise
In the last 3 months, VRTX stock has moved up by 15.0%
NO EFFECTAgainst Peers
In the last 1 year, Insmed Incorporated has given 175.0% return, outperforming this stock by 177.5%
- NO EFFECT
Against Peers
In the last 3 years, Insmed Incorporated has given 912.4% return, outperforming this stock by 865.8%
About Vertex Pharmaceuticals Incorporated
| Organisation | Vertex Pharmaceuticals Incorporated |
| Headquarters | 50 Northern Avenue, Boston, MA, United States, 02210 |
| Industry | Health Technology |
| CEO | Dr. Reshma Kewalramani FASN, M.D. |
| E-voting on shares | Click here to vote |
Key Management of Vertex Pharmaceuticals Incorporated
Name | Title |
|---|---|
Ms. Stephanie Franklin | Senior VP & Chief Human Resources Officer |
Mr. Charles F. Wagner Jr. | Executive VP, COO & CFO |
Dr. David M. Altshuler M.D., Ph.D. | Executive VP & Chief Scientific Officer |
Mr. Jonathan Biller J.D. | Executive VP & Chief Legal Officer |
Ms. Kristen C. Ambrose CPA | Senior VP & Chief Accounting Officer |
Ms. Susie Lisa C.F.A. | Senior Vice President of Investor Relations |
Ms. Nina Devlin | Senior VP & Chief Communications Officer |
Dr. Jeffrey Marc Leiden M.D., Ph.D. | Executive Chairman |
Dr. Reshma Kewalramani FASN, M.D. | CEO, President & Director |
Dr. Ourania Tatsis Ph.D. | Executive VP and Chief Regulatory & Quality Officer |
FAQs
What is Vertex Pharmaceuticals Incorporated share price today?
Vertex Pharmaceuticals Incorporated share price today is $452.23 as on at the close of the market. Vertex Pharmaceuticals Incorporated share today touched a day high of $456 and a low of $444.98.
What is the 52 week high and 52 week low for Vertex Pharmaceuticals Incorporated share?
Vertex Pharmaceuticals Incorporated share touched a 52 week high of $519.68 on and a 52 week low of $362.5 on . Vertex Pharmaceuticals Incorporated stock price today i.e. is closed at $452.23,which is 12.98% down from its 52 week high and 24.75% up from its 52 week low.
What is Vertex Pharmaceuticals Incorporated's market capitalisation today?
Vertex Pharmaceuticals Incorporated market capitalisation is $0.12T as on .
How to invest in Vertex Pharmaceuticals Incorporated Stock (VRTX) from India?
- Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
- Step 2: Search for Vertex Pharmaceuticals Incorporated on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Vertex Pharmaceuticals Incorporated Shares that will get you 0.0033 shares as per Vertex Pharmaceuticals Incorporated share price of $452.23 per share as on December 13, 2025 at 2:29 am IST.
What is the minimum amount required to buy Vertex Pharmaceuticals Incorporated Stock (VRTX) from India?
Indian investors can start investing in Vertex Pharmaceuticals Incorporated (VRTX) shares with as little as ₹90.544 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹905.44 in Vertex Pharmaceuticals Incorporated stock (as per the Rupee-Dollar exchange rate as on ).
Based on Vertex Pharmaceuticals Incorporated share’s latest price of $452.23 as on December 13, 2025 at 2:29 am IST, you will get 0.0221 shares of Vertex Pharmaceuticals Incorporated. Learn more about
fractional shares .
What are the returns that Vertex Pharmaceuticals Incorporated has given to Indian investors in the last 5 years?
Vertex Pharmaceuticals Incorporated stock has given 97.56% share price returns and 22.56% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?