Vertex Pharmaceuticals Incorporated share price logo

Vertex Pharmaceuticals Incorporated Share Price

NASDAQ: VRTX

Large Cap

$386.99

-0.16

(-0.04%)

Live

as on

Vertex Pharmaceuticals Incorporated Stock Performance

as on September 19, 2025 at 12:42 am IST

  • Day's Low

    Day's High

    $384.87
    $390.66
    downward going graph

    0.55%

    Downside

    0.95%

    Upside

    downward going graph
  • 52 Week's Low

    52 Week's High

    $362.5
    $519.88
    downward going graph

    6.33%

    Downside

    34.34%

    Upside

    downward going graph

Vertex Pharmaceuticals Incorporated share price movements today

Previous Close
$387.15
Open
$389.69
Volume
1.1M
Day's Low - High
$384.87 - $390.66
52 Week Low - High
$362.5 - $519.88

Vertex Pharmaceuticals Incorporated Historical Returns

1 Month Return
-0.7 %
3 Month Return
-13.66 %
1 Year Return
-18.35 %
3 Year Return
+ 33.63 %
5 Year Return
+ 45.88 %

Vertex Pharmaceuticals Incorporated Stock Fundamentals & Key Indicators

Check Vertex Pharmaceuticals Incorporated market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$99.3B

EPS (TTM)

18.0327

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

-0.41%

PE Ratio (TTM)

27.56

Industry PE ratio

16.65525641025641

P/B Ratio

27.5552

PEG Ratio

0.5801

EBITDA

4.8B

Revenue (TTM)

11.4B

Profit Margin

31.86%

Return On Equity TTM

22.77%

Vertex Pharmaceuticals Incorporated Stock Valuation

Track how Vertex Pharmaceuticals Incorporated P/E has moved over time to understand its valuation trends.

Vertex Pharmaceuticals Incorporated in the last 5 years

  • Overview

  • Trends

Lowest (14.94x)

December 31, 2021

Industry (16.66x)

September 18, 2025

Today (27.56x)

September 18, 2025

Highest (29.01x)

September 30, 2020

LowHigh

Today’s Price to Earnings Ratio: 27.56x

Vertex Pharmaceuticals Incorporated vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Vertex Pharmaceuticals Incorporated with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %
BUY$99.3B45.88%27.5631.86%
BUY$60.5B241.54%-505.15-12.96%
NA$38.7BNANA-3.89%
BUY$60.9B5.45%14.4931.37%

Stock Returns calculator for Vertex Pharmaceuticals Incorporated Stock including INR - Dollar returns

The Vertex Pharmaceuticals Incorporated stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.

Investment Value

₹1,00,000

  • 1Y

  • 3Y

  • 5Y

  • 7Y

  • 10Y

Vertex Pharmaceuticals Incorporated investment value today

Current value as on today

₹86,569

Returns

₹13,431

(-13.43%)

Returns from Vertex Pharmaceuticals Incorporated Stock

₹18,384 (-18.38%)

Dollar Returns*

₹4,953 (+4.95%)

Analyst Recommendation on Vertex Pharmaceuticals Incorporated Stock

Based on 38 analysts

BUY

68.42%

Buy

26.32%

Hold

5.26%

Sell

Based on 38 analysts, 68.42% of analysts recommend a 'BUY' rating for Vertex Pharmaceuticals Incorporated. Average target price of $479.64

Vertex Pharmaceuticals Incorporated Share Price Target

Get share price movements and forecasts by analysts on Vertex Pharmaceuticals Incorporated.

What analysts predicted

19.32%UPSIDE

Target Price

$479.64

Current Price

$386.99

Analyzed by

38 Analysts

Target

$479.64

Vertex Pharmaceuticals Incorporated target price $479.64, a slight upside of 19.32% compared to current price of $386.99. According to 38 analysts rating.

Vertex Pharmaceuticals Incorporated Stock's Interest Amongst Investors

Investment in Vertex Pharmaceuticals Incorporated Shares on INDmoney has dropped by -45.18% over the past 30 days, indicating reduced transactional activity.

Time period: to

Change:-45.18% versus previous 30 day period

Search interest for Vertex Pharmaceuticals Incorporated Stock has decreased by -42% in the last 30 days, reflecting a downward trend in search activity.

Time period: to

Change:-42% versus previous 30 day period

Vertex Pharmaceuticals Incorporated Quarterly Profit & Loss

All numbers in Millions USD

Mar 2023
Jun 2023
Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Total Revenue
2,374
2,493
2,483
2,517
2,687
2,645
2,771
2,912
2,770
2,964
Gross Profit
2,107
2,184
2,164
2,149
2,344
2,273
2,379
2,488
2,407
2,557
Operating Income
779
1,026
1,038
988
1,139
-3,514
1,116
1,026
630
1,151
EBITDA
941
1,214
1,232
1,217
1,343
-3,327
1,284
1,184
781
1,422
Interest Expense
11
11
10
10
10
9
7
2
3
3
Depreciation
38
41
42
59
53
54
53
46
48
51
Income Before Tax
891
1,161
1,179
1,147
1,279
-3,391
1,224
1,136
730
1,283
Income Tax Expense
191
245
143
178
179
202
178
223
84
250
Net Income
699
915
1,035
968
1,099
-3,593
1,045
913
646
1,032
Net Profit Margin
29.47%
36.73%
41.69%
38.48%
40.92%
-135.83%
37.71%
31.35%
23.33%
34.84%

Vertex Pharmaceuticals Incorporated Annual Profit & Loss

All numbers in Millions USD

Dec 2015
Dec 2016
Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Total Revenue
1,032
1,702
2,488
3,047
4,162
6,205
7,574
8,930
9,869
11,020
Gross Profit
906
1,491
2,213
2,638
3,615
5,469
6,670
7,850
8,607
9,489
Operating Income
-468
9
123
635
1,197
2,856
2,782
4,307
3,832
-232
EBITDA
-411
75
103
706
1,560
3,284
2,917
4,435
4,605
486
Interest Expense
84
81
69
34
58
58
61
54
44
30
Depreciation
-
-
61
72
106
109
125
148
181
207
Income Before Tax
-559
-67
-15
600
1,394
3,116
2,730
4,232
4,379
248
Income Tax Expense
30
16
-107
-1,486
218
405
388
910
760
784
Net Income
-558
-112
263
2,096
1,176
2,711
2,342
3,322
3,619
-535
Net Profit Margin
-54.06%
-6.58%
10.59%
68.80%
28.27%
43.70%
30.92%
37.20%
36.68%
-4.86%

Vertex Pharmaceuticals Incorporated Quarterly Cash Flow

All numbers in Millions USD

Jun 2023
Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Net Income
915
1,035
968
1,099
-3,593
1,045
913
646
1,032
Operating Cash Flow
1,134
1,268
234
1,306
-3,753
1,369
584
818
1,073
Investing Cash Flow
-303
-117
-886
-2,136
-463
-348
-821
-55
-484
Financing Cash Flow
17
-165
-119
-357
-358
-387
-391
-680
-349
Change in Cash
857
963
-744
-1,202
-4,578
657
-675
113
296

Vertex Pharmaceuticals Incorporated Annual Cash Flow

All numbers in Millions USD

Dec 2016
Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Net Income
-84
91
2,087
1,176
2,711
2,342
3,322
3,619
-535
Operating Cash Flow
236
844
1,270
1,569
3,253
2,643
4,129
3,537
-492
Investing Cash Flow
104
-437
-202
-1,235
99
-340
-321
-3,141
-3,770
Financing Cash Flow
133
68
-71
126
-505
-1,478
-67
-562
-1,494
Change in Cash
469
481
990
462
2,868
811
3,711
-139
-5,800

Global Institutional Holdings in Vertex Pharmaceuticals Incorporated

Funds
Holdings
Capital World Investors
11.13%
Vanguard Group Inc
9.16%
BlackRock Inc
8.5%
Capital Research Global Investors
5.67%
State Street Corp
4.6%

Vertex Pharmaceuticals Incorporated News & Key Events

  • img

    Today's Timeline - 05 August

    Tue, 10:20 AM

    -

    TD Cowen analyst maintains Buy rating on Vertex, citing strong financials despite VX-993 trial failure.

    Tue, 02:29 PM

    -

    Vertex announces VX-993 failed Phase 2 trial, leading to a 14% stock drop despite strong Q2 results.

    Tue, 04:04 PM

    -

    Vertex shares slide 14% after announcing it won't proceed with advanced testing of its experimental painkiller.

Insights on Vertex Pharmaceuticals Incorporated

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Profit Spike

    img

    Vertex Pharmaceuticals Incorporated has shown a positive trend in its net profit over the last two quarters. The net profit increased from $646.3 million to $1.03 billion, reflecting an average increase of 37.4% per quarter.

  • imgPOSITIVE IMPACT

    Revenue Rich

    img

    Vertex Pharmaceuticals Incorporated has shown a positive revenue trend over the last two quarters. In the most recent quarter, the revenue increased to $2.96 billion, up from $2.77 billion in the previous quarter. This represents an average increase of 6.6% in revenue each quarter.

  • imgNO EFFECT

    Against Peers

    img

    In the last 1 year, Beone Medicines Ltd has given 68.4% return, outperforming this stock by 86.8%

  • imgNO EFFECT

    Against Peers

    img

    In the last 3 years, Alnylam Pharmaceuticals, Inc. has given 111.5% return, outperforming this stock by 77.9%

  • imgNEGATIVE IMPACT

    Price Dip

    img

    In the last 3 months, VRTX stock has moved down by -13.7%

About Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry.
OrganisationVertex Pharmaceuticals Incorporated
Headquarters50 Northern Avenue, Boston, MA, United States, 02210
IndustryHealth Technology
CEODr. Reshma Kewalramani FASN, M.D.
E-voting on sharesClick here to vote

Key Management of Vertex Pharmaceuticals Incorporated

Name

Title

Dr. Jeffrey Marc Leiden M.D., Ph.D.

Executive Chairman

Mr. Charles F. Wagner Jr.

Executive VP, COO & CFO

Dr. David M. Altshuler M.D., Ph.D.

Executive VP & Chief Scientific Officer

Dr. Ourania Tatsis Ph.D.

Executive VP and Chief Regulatory & Quality Officer

Ms. Nina Devlin

Senior VP & Chief Communications Officer

Dr. Reshma Kewalramani FASN, M.D.

CEO, President & Director

Ms. Kristen C. Ambrose CPA

Senior VP & Chief Accounting Officer

Ms. Susie Lisa C.F.A.

Senior Vice President of Investor Relations

Mr. Jonathan Biller J.D.

Executive VP & Chief Legal Officer

Ms. Stephanie Franklin

Senior VP & Chief Human Resources Officer

FAQs

What is Vertex Pharmaceuticals Incorporated share price today?

Vertex Pharmaceuticals Incorporated share price today is $386.99 as on . Vertex Pharmaceuticals Incorporated share today touched a day high of $390.66 and a low of $384.87.

What is the 52 week high and 52 week low for Vertex Pharmaceuticals Incorporated share?

Vertex Pharmaceuticals Incorporated share touched a 52 week high of $519.88 on and a 52 week low of $362.5 on . Vertex Pharmaceuticals Incorporated stock price today i.e. is trending at $386.99,which is 25.56% down from its 52 week high and 6.76% up from its 52 week low.

What is Vertex Pharmaceuticals Incorporated's market capitalisation today?

Vertex Pharmaceuticals Incorporated market capitalisation is $0.10T as on .

How to invest in Vertex Pharmaceuticals Incorporated Stock (VRTX) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Vertex Pharmaceuticals Incorporated on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Vertex Pharmaceuticals Incorporated Shares that will get you 0.0039 shares as per Vertex Pharmaceuticals Incorporated share price of $386.99 per share as on September 19, 2025 at 12:42 am IST.

What is the minimum amount required to buy Vertex Pharmaceuticals Incorporated Stock (VRTX) from India?

Indian investors can start investing in Vertex Pharmaceuticals Incorporated (VRTX) shares with as little as ₹88.114 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹881.14 in Vertex Pharmaceuticals Incorporated stock (as per the Rupee-Dollar exchange rate as on ). Based on Vertex Pharmaceuticals Incorporated share’s latest price of $386.99 as on September 19, 2025 at 12:42 am IST, you will get 0.0258 shares of Vertex Pharmaceuticals Incorporated. Learn more about fractional shares .

What are the returns that Vertex Pharmaceuticals Incorporated has given to Indian investors in the last 5 years?

Vertex Pharmaceuticals Incorporated stock has given 45.88% share price returns and 20.01% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?