Lyra Therapeutics Inc share price logo

Lyra Therapeutics Inc Share Price

NASDAQ: LYRA

Small Cap

$6.26

-0.03

(-0.40%)

as on

Lyra Therapeutics Inc Stock Performance

as on September 16, 2025 at 1:17 am IST

  • Day's Low

    Day's High

    $6.19
    $6.34
    downward going graph

    1.12%

    Downside

    1.28%

    Upside

    downward going graph
  • 52 Week's Low

    52 Week's High

    $3.81
    $37.5
    downward going graph

    39.14%

    Downside

    499.04%

    Upside

    downward going graph

Lyra Therapeutics Inc share price movements today

Previous Close
$6.29
Open
$6.28
Volume
102.7K
Day's Low - High
$6.19 - $6.34
52 Week Low - High
$3.81 - $37.5

Lyra Therapeutics Inc Historical Returns

1 Month Return
-10.78 %
3 Month Return
-44.53 %
1 Year Return
-55.07 %
3 Year Return
-97.89 %
5 Year Return
-98.91 %

Lyra Therapeutics Inc Stock Fundamentals & Key Indicators

Check Lyra Therapeutics Inc market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$10.3M

EPS (TTM)

-21

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.00%

PE Ratio (TTM)

-0.2

Industry PE ratio

0

P/B Ratio

0

PEG Ratio

0

EBITDA

-35.3M

Revenue (TTM)

770.0K

Profit Margin

0.00%

Return On Equity TTM

60022000.00%

Lyra Therapeutics Inc Stock Valuation

Track how Lyra Therapeutics Inc P/E has moved over time to understand its valuation trends.

Lyra Therapeutics Inc in the last 5 years

  • Overview

  • Trends

Lowest (0.00x)

September 15, 2025

Industry (0.00x)

September 15, 2025

Today (-0.20x)

September 15, 2025

Highest (0.00x)

September 15, 2025

LowHigh

Today’s Price to Earnings Ratio: -0.20x

Lyra Therapeutics Inc vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Lyra Therapeutics Inc with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %
BUY$10.3M-98.91%-0.20.00%
BUY$61.1B256.98%-505.15-12.96%
NA$38.7BNANA-3.89%
BUY$101.1B47.85%28.0731.86%
BUY$59.4B-3.43%14.1131.37%

Stock Returns calculator for Lyra Therapeutics Inc Stock including INR - Dollar returns

The Lyra Therapeutics Inc stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.

Investment Value

₹1,00,000

  • 1Y

  • 3Y

  • 5Y

Lyra Therapeutics Inc investment value today

Current value as on today

₹49,700

Returns

₹50,300

(-50.3%)

Returns from Lyra Therapeutics Inc Stock

₹55,286 (-55.29%)

Dollar Returns*

₹4,985 (+4.99%)

Analyst Recommendation on Lyra Therapeutics Inc Stock

Based on 12 analysts

BUY

91.67%

Buy

8.33%

Hold

0.00%

Sell

Based on 12 analysts, 91.67% of analysts recommend a 'BUY' rating for Lyra Therapeutics Inc. Average target price of $11.5

Lyra Therapeutics Inc Share Price Target

Get share price movements and forecasts by analysts on Lyra Therapeutics Inc.

What analysts predicted

45.57%UPSIDE

Target Price

$11.5

Current Price

$6.26

Analyzed by

12 Analysts

Target

$11.50

Lyra Therapeutics Inc target price $11.5, a slight upside of 45.57% compared to current price of $6.26. According to 12 analysts rating.

Lyra Therapeutics Inc Stock's Interest Amongst Investors

Search interest for Lyra Therapeutics Inc Stock has decreased by -50% in the last 30 days, reflecting a downward trend in search activity.

Time period: to

Change:-50% versus previous 30 day period

Lyra Therapeutics Inc Quarterly Profit & Loss

All numbers in Millions USD

Mar 2023
Jun 2023
Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Total Revenue
0
0
0
0
0
0
0
0
0
0
Gross Profit
0
-10
-11
0
0
-12
0
0
0
0
Operating Income
-17
-16
-16
-16
-23
-48
-12
-11
-8
-8
EBITDA
-17
-14
-16
-16
-23
-17
-9
-9
-8
-7
Interest Expense
1
-
-
1
-
-
-
-
-
-
Depreciation
0
0
0
0
0
0
0
0
0
0
Income Before Tax
-16
-15
-15
-15
-22
-48
-11
-10
-8
-7
Income Tax Expense
0
0
0
0
0
0
0
0
0
0
Net Income
-16
-15
-15
-15
-22
-48
-11
-10
-8
-7
Net Profit Margin
-3964.63%
-3410.04%
-2877.02%
-10380.82%
-4220.30%
-8048.66%
-6088.72%
-5253.11%
-4670.49%
-4063.93%

Lyra Therapeutics Inc Annual Profit & Loss

All numbers in Millions USD

Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Total Revenue
1
-
-
0
1
1
1
Gross Profit
1
0
0
0
0
1
1
Operating Income
-7
-16
-22
-43
-56
-67
-96
EBITDA
-7
-16
-22
-42
-53
-65
-60
Interest Expense
1
0
0
0
0
-
-
Depreciation
0
0
0
1
1
0
0
Income Before Tax
-6
-16
-22
-43
-55
-62
-93
Income Tax Expense
-1
0
0
-1
0
0
0
Net Income
-6
-16
-22
-42
-55
-62
-93
Net Profit Margin
-484.65%
0.00%
0.00%
-14880.70%
-4055.61%
-4023.11%
-6090.94%

Lyra Therapeutics Inc Quarterly Cash Flow

All numbers in Millions USD

Jun 2023
Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Net Income
-15
-15
-15
-22
-48
-11
-10
-8
-7
Operating Cash Flow
-14
-14
-19
-22
-19
-16
-11
-8
-6
Investing Cash Flow
0
-14
-2
7
36
8
28
-
0
Financing Cash Flow
47
0
18
8
0
0
0
-
4
Change in Cash
32
-29
-2
-6
16
-8
16
-8
-1

Lyra Therapeutics Inc Annual Cash Flow

All numbers in Millions USD

Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Net Income
-16
-22
-43
-55
-62
-93
Operating Cash Flow
-13
-21
-25
-43
-63
-70
Investing Cash Flow
0
-1
-3
-65
-12
80
Financing Cash Flow
0
87
0
96
65
8
Change in Cash
-14
64
-28
-12
-10
18

Global Institutional Holdings in Lyra Therapeutics Inc

Funds
Holdings
Perceptive Advisors LLC
15.96%
BlackRock Inc
3.78%
Vanguard Group Inc
2.21%
Samsara BioCapital, LLC
1.74%
Ikarian Capital, LLC
1.32%

Insights on Lyra Therapeutics Inc

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Profit Spike

    img

    Netprofit is up for the last 5 quarters, -48.13M → -7.43M (in $), with an average increase of 89.2% per quarter

  • imgNO EFFECT

    Against Peers

    img

    In the last 3 years, Alnylam Pharmaceuticals, Inc. has given 123.5% return, outperforming this stock by 221.4%

  • imgNO EFFECT

    Against Peers

    img

    In the last 1 year, Alnylam Pharmaceuticals, Inc. has given 75.6% return, outperforming this stock by 130.7%

  • imgNEGATIVE IMPACT

    Price Dip

    img

    In the last 1 month, LYRA stock has moved down by -10.8%

  • imgNEGATIVE IMPACT

    Revenue Fall

    img

    Revenue is down for the last 3 quarters, 209.0K → 183.0K (in $), with an average decrease of 6.2% per quarter

About Lyra Therapeutics Inc

lyra therapeutics, inc., a clinical-stage therapeutics company, focuses on the development and commercialization of novel integrated drug and delivery solutions for the localized treatment of patients with ear, nose, and throat diseases. the company's xtreo technology platform is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. its product candidates include lyr-210 and lyr-220, which are bioresorbable polymeric matrices for the treatment of chronic rhinosinusitis. the company was formerly known as 480 biomedical, inc. and changed its name to lyra therapeutics, inc. in july 2018. lyra therapeutics, inc. was founded in 2005 and is headquartered in watertown, massachusetts.
OrganisationLyra Therapeutics Inc
Headquarters480 Arsenal Way, Watertown, MA, United States, 02472
IndustryHealth Technology
CEODr. Maria Palasis Ph.D.
E-voting on sharesClick here to vote

Key Management of Lyra Therapeutics Inc

Name

Title

Ms. Allison Nance

Senior Vice President of Regulatory Affairs

Mr. Ronan P. O'Brien J.D.

Chief Legal Officer

Ms. Vineeta Belanger Ph.D.

Senior Vice President of Clinical Affairs

Dr. Robert Kern M.D.

Chief Clinical Advisor

Ms. Gloria Cosgrove

Senior Vice President of Quality

Dr. Maria Palasis Ph.D.

CEO, President & Chairman

Mr. Jason Cavalier

CFO, Treasurer & Secretary

Dr. Carmichael S. Roberts Jr., Ph.D.

Co-Founder

Dr. Elazer R. Edelman FACC, M.D., Ph.D.

VP of Finance & Risk

FAQs

What is Lyra Therapeutics Inc share price today?

Lyra Therapeutics Inc share price today is $6.26 as on at the close of the market. Lyra Therapeutics Inc share today touched a day high of $6.34 and a low of $6.19.

What is the 52 week high and 52 week low for Lyra Therapeutics Inc share?

Lyra Therapeutics Inc share touched a 52 week high of $37.5 on and a 52 week low of $3.81 on . Lyra Therapeutics Inc stock price today i.e. is closed at $6.26,which is 83.31% down from its 52 week high and 64.30% up from its 52 week low.

What is Lyra Therapeutics Inc's market capitalisation today?

Lyra Therapeutics Inc market capitalisation is $0.00T as on .

How to invest in Lyra Therapeutics Inc Stock (LYRA) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Lyra Therapeutics Inc on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Lyra Therapeutics Inc Shares that will get you 0.2396 shares as per Lyra Therapeutics Inc share price of $6.26 per share as on September 16, 2025 at 1:17 am IST.

What is the minimum amount required to buy Lyra Therapeutics Inc Stock (LYRA) from India?

Indian investors can start investing in Lyra Therapeutics Inc (LYRA) shares with as little as ₹88.141 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹881.41 in Lyra Therapeutics Inc stock (as per the Rupee-Dollar exchange rate as on ). Based on Lyra Therapeutics Inc share’s latest price of $6.26 as on September 16, 2025 at 1:17 am IST, you will get 1.5974 shares of Lyra Therapeutics Inc. Learn more about fractional shares .

What are the returns that Lyra Therapeutics Inc has given to Indian investors in the last 5 years?

Lyra Therapeutics Inc stock has given -98.91% share price returns and 20.01% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?