Bicycle Therapeutics plc American Depositary Shares share price logo

Bicycle Therapeutics plc American Depositary Shares

NASDAQ: BCYC

Small Cap

$4.00

+0.02

(+0.50%)

as on

Bicycle Therapeutics plc American Depositary Shares Stock Performance

as on June 24, 2026 at 2:16 pm IST

  • Day's Low

    Day's High

    $3.98
    $4.13
    downward going graph

    0.50%

    Downside

    3.25%

    Upside

    downward going graph

  • 52 Week's Low

    52 Week's High

    $3.95
    $9.18
    downward going graph

    1.25%

    Downside

    129.58%

    Upside

    downward going graph

Bicycle Therapeutics plc American Depositary Shares share price movements today

Previous Close
$3.98
Open
$3.98
Volume
525.4K
Day's Low - High
$3.98 - $4.13
52 Week Low - High
$3.95 - $9.18

Bicycle Therapeutics plc American Depositary Shares Historical Returns

1 Month Return
-12.09 %
3 Month Return
-11.11 %
1 Year Return
-45.28 %
3 Year Return
-84.19 %
5 Year Return
-87.2 %

Bicycle Therapeutics plc American Depositary Shares Stock Fundamentals & Key Indicators

Check Bicycle Therapeutics plc American Depositary Shares market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$277.8M

EPS (TTM)

-2.275

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.00%

PE Ratio (TTM)

0

PEG Ratio

0

EBITDA

-232.2M

Revenue (TTM)

63.5M

Profit Margin

0.00%

Return On Equity TTM

-33.84%

Bicycle Therapeutics plc American Depositary Shares vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Bicycle Therapeutics plc American Depositary Shares with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %Dividend Yield %
Bicycle Therapeutics plc American Depositary Shares image
Bicycle Therapeutics plc American Depositary Shares
BUY$277.8M-87.2%NA0.00%NA
Alnylam Pharmaceuticals Common Stock image
Alnylam Pharmaceuticals Common Stock
BUY$38.2B65.93%71.9612.55%NA
Vertex PharmaceuticalsCommon Stock image
Vertex PharmaceuticalsCommon Stock
BUY$118.5B144.05%27.735.51%NA
Regeneron Pharmaceuticals Common Stock image
Regeneron Pharmaceuticals Common Stock
BUY$64.2B13.51%14.9529.65%0.59%

Stock Returns calculator for Bicycle Therapeutics plc American Depositary Shares Stock including INR - Dollar returns

The Bicycle Therapeutics plc American Depositary Shares stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.

Investment Value

₹1,00,000

  • 1Y

  • 3Y

  • 5Y

  • 7Y

Bicycle Therapeutics plc American Depositary Shares investment value today

Current value as on today

₹59,874

Returns

-₹40,126

(-40.13%)

Returns from Bicycle Therapeutics plc American Depositary Shares Stock

-₹45,280 (-45.28%)

Dollar Impact

₹5,154 (+5.15%)

Analyst Recommendation on Bicycle Therapeutics plc American Depositary Shares Stock

Based on 18 analysts

BUY

88.89%

Buy

11.11%

Hold

0.00%

Sell

Based on 18 analysts, 88.89% of analysts recommend a 'BUY' rating for Bicycle Therapeutics plc American Depositary Shares. Average target price of $12.62

Bicycle Therapeutics plc American Depositary Shares Share Price Target

Get share price movements and forecasts by analysts on Bicycle Therapeutics plc American Depositary Shares.

What analysts predicted

68.3%UPSIDE

Target Price

$12.62

Current Price

$4

Analyzed by

18 Analysts

Target

$12.62

Bicycle Therapeutics plc American Depositary Shares target price $12.62, a slight upside of 68.3% compared to current price of $4. According to 18 analysts rating.

Indian Investors' Interest in Bicycle Therapeutics plc American Depositary Shares Stock

Search interest for Bicycle Therapeutics plc American Depositary Shares Stock has decreased by -70% in the last 30 days, reflecting a downward trend in search activity.

Time period: to

Change:-70% versus previous 30 day period

Bicycle Therapeutics plc American Depositary Shares Quarterly Profit & Loss

All numbers in Millions USD

Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Mar 2026
Total Revenue
5
19
9
2
3
9
2
11
47
0
Gross Profit
5
19
9
-42
-52
-47
-68
11
47
0
Operating Income
-54
-31
-46
-63
-67
-70
-86
-65
-24
-65
EBITDA
-46
-24
-37
-61
-51
-70
-77
-57
-17
-59
Interest Expense
0
0
0
0
0
0
0
0
0
0
Depreciation
1
1
1
2
1
1
1
1
1
1
Income Before Tax
-48
-26
-39
-54
-52
-61
-79
-58
-18
-60
Income Tax Expense
0
0
0
-3
-1
-1
0
0
1
0
Net Income
-49
-26
-39
-50
-51
-60
-78
-59
-20
-60
Net Profit Margin
-921.01%
-136.01%
-425.30%
-1898.43%
-1398.44%
-608.94%
-2703.84%
-503.66%
-42.03%
-6857.38%

Bicycle Therapeutics plc American Depositary Shares Annual Profit & Loss

All numbers in Millions USD

Dec 2016
Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Total Revenue
-
2
7
13
10
11
14
26
35
72
Gross Profit
0
-9
-13
13
-22
11
14
-129
-137
72
Operating Income
-13
-16
-21
-26
-51
-65
-116
-189
-209
-247
EBITDA
-13
-15
-21
-25
-50
-64
-107
-169
-164
-212
Interest Expense
-
-
-
3
0
2
3
3
1
0
Depreciation
-
0
0
0
1
1
3
6
7
6
Income Before Tax
-13
-16
-22
-30
-51
-68
-114
-179
-173
-218
Income Tax Expense
0
0
0
0
0
-1
-1
1
-4
0
Net Income
-13
-16
-21
-30
-51
-66
-112
-180
-169
-218
Net Profit Margin
0.00%
-789.27%
-306.14%
-221.78%
-490.95%
-571.25%
-779.35%
-669.72%
-479.18%
-301.66%

Bicycle Therapeutics plc American Depositary Shares Quarterly Cash Flow

All numbers in Millions USD

Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Mar 2026
Net Income
-26
-39
-51
-51
-60
-78
-59
-19
-60
Operating Cash Flow
-70
-44
-39
-9
-86
-72
-71
-19
-65
Investing Cash Flow
0
0
0
0
0
0
0
0
0
Financing Cash Flow
1
549
-31
0
0
0
0
0
0
Change in Cash
-69
504
-70
-11
-86
-71
-73
-19
-68

Bicycle Therapeutics plc American Depositary Shares Annual Cash Flow

All numbers in Millions USD

Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Net Income
-16
-21
-30
-51
-66
-112
-180
-169
-218
Operating Cash Flow
-1
-26
-28
-17
-14
-86
-60
-164
-249
Investing Cash Flow
-1
-1
-1
-1
-2
-18
-2
-1
-2
Financing Cash Flow
57
25
58
62
320
6
250
519
0
Change in Cash
58
-4
28
43
302
-99
187
353
-251

Global Institutional Holdings in Bicycle Therapeutics plc American Depositary Shares

Funds
Holdings
Siren, L.L.C.
2.24%
Diadema Partners LP
0.68%
Birchview Capital, LP
0.66%
Candriam Luxembourg S.C.A.
1.71%
BNP Paribas Investment Partners SA
1.5%
See all

Insights on Bicycle Therapeutics plc American Depositary Shares

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgNO EFFECT

    Against Peers

    img

    In the last 3 years, Bicycle Therapeutics plc American Depositary Shares has experienced a drawdown of -84.2%, however Alnylam Pharmaceuticals, Inc. Common Stock resisted the overall trend and outperformed by 63.5%

  • imgNO EFFECT

    Against Peers

    img

    In the last 1 year, Regeneron Pharmaceuticals, Inc. Common Stock has given 18.3% return, outperforming this stock by 63.6%

  • imgNEGATIVE IMPACT

    Profit Down

    img

    Netprofit is down for the last 2 quarters, -20.15M → -60.82M (in $), with an average decrease of 201.8% per quarter

  • imgNEGATIVE IMPACT

    Revenue Fall

    img

    Revenue is down for the last 2 quarters, 47.95M → 887.0K (in $), with an average decrease of 98.2% per quarter

  • imgNEGATIVE IMPACT

    Price Dip

    img

    In the last 3 years, BCYC stock has moved down by -84.2%

About Bicycle Therapeutics plc American Depositary Shares

Bicycle Therapeutics plc, a clinical-stage pharmaceutical company, develops a class of medicines for diseases that are underserved by existing therapeutics in the United States and the United Kingdom. The company's products pipeline include zelenectide pevedotin, a bicycle toxin conjugate (BTC), which is in phase II clinical trials for the treatment of high nectin-4 expressing tumors; nuzefatide pevedotin (EphA2), a BTC that is in phase I/II clinical trials to treat Ephrin type A receptor 2 expressing tumor; BT7480, a Bicycle tumor-targeted immune cell agonist molecule, which is in phase I/II targeting nectin-4 and agonizing CD137; and BT1702, a theranostic BRC molecule targeting MT1-MMP for which IND-enabling activities are ongoing. In addition, it develops Novel CNS targets, which is in preclinical trial targeting CNS disease; Novel neuromuscular targets, which is in preclinical trial targeting neuromuscular disease; and programs that are in preclinical trial targeting radiopharmaceutical. Further, the company collaborates with biopharmaceutical companies and organizations to develop programs in therapeutic areas. It has collaboration and license agreement with Bayer Consumer Care AG; Novartis Pharma AG; Ionis Pharmaceuticals, Inc.; Genentech, Inc; and AstraZeneca AB. Bicycle Therapeutics plc was incorporated in 2009 and is headquartered in Cambridge, the United Kingdom.
OrganisationBicycle Therapeutics plc American Depositary Shares
HeadquartersPortway Building, Cambridge, United Kingdom, CB21 6GS
IndustryBiotechnology
CEODr. Kevin Lee M.B.A., Ph.D.
E-voting on sharesClick here to vote

Key Management of Bicycle Therapeutics plc American Depositary Shares

Name

Title

Dr. Kevin Lee M.B.A., Ph.D.

CEO & Executive Director

FAQs

What is Bicycle Therapeutics plc American Depositary Shares share price today?

Bicycle Therapeutics plc American Depositary Shares share price today is $4 as on at the close of the market. Bicycle Therapeutics plc American Depositary Shares share today touched a day high of $4.13 and a low of $3.98.

What is the 52 week high and 52 week low for Bicycle Therapeutics plc American Depositary Shares share?

Bicycle Therapeutics plc American Depositary Shares share touched a 52 week high of $9.18 on and a 52 week low of $3.95 on . Bicycle Therapeutics plc American Depositary Shares stock price today i.e. is closed at $4,which is 56.44% down from its 52 week high and 1.27% up from its 52 week low.

What is Bicycle Therapeutics plc American Depositary Shares's market capitalisation today?

Bicycle Therapeutics plc American Depositary Shares market capitalisation is $0.00T as on .

How to invest in Bicycle Therapeutics plc American Depositary Shares Stock (BCYC) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Bicycle Therapeutics plc American Depositary Shares on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Bicycle Therapeutics plc American Depositary Shares Shares that will get you 0.3750 shares as per Bicycle Therapeutics plc American Depositary Shares share price of $4 per share as on June 24, 2026 at 8:46 am IST.

What is the minimum amount required to buy Bicycle Therapeutics plc American Depositary Shares Stock (BCYC) from India?

Indian investors can start investing in Bicycle Therapeutics plc American Depositary Shares (BCYC) shares with as little as ₹94.735 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹947.35 in Bicycle Therapeutics plc American Depositary Shares stock (as per the Rupee-Dollar exchange rate as on ). Based on Bicycle Therapeutics plc American Depositary Shares share’s latest price of $4 as on June 24, 2026 at 8:46 am IST, you will get 2.5000 shares of Bicycle Therapeutics plc American Depositary Shares. Learn more about fractional shares .

What are the returns that Bicycle Therapeutics plc American Depositary Shares has given to Indian investors in the last 5 years?

Bicycle Therapeutics plc American Depositary Shares stock has given -87.2% share price returns and 27.69% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?