Castle Biosciences share price logo

Castle Biosciences

NASDAQ: CSTL

Small Cap

$35.34

-1.44

(-3.92%)

as on

Castle Biosciences Stock Performance

as on September 19, 2026 at 2:16 pm IST

  • Day's Low

    Day's High

    $35.38
    $36.54
    downward going graph

    -0.11%

    Downside

    3.40%

    Upside

    downward going graph

  • 52 Week's Low

    52 Week's High

    $17.72
    $44.28
    downward going graph

    49.85%

    Downside

    25.30%

    Upside

    downward going graph

Castle Biosciences share price movements today

Previous Close
$36.78
Open
$36.54
Volume
496.6K
Market Cap
$1.1B
Day's Low - High
$35.38 - $36.54
52 Week Low - High
$17.72 - $44.28

Castle Biosciences Historical Returns

1 Month Return
+ 13.8 %
3 Month Return
+ 74.15 %
1 Year Return
+ 50.68 %
3 Year Return
+ 119.32 %
5 Year Return
-52.43 %

Castle Biosciences Stock Fundamentals & Key Indicators

Check Castle Biosciences market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$1.1B

EPS (TTM)

-0.6595

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.00%

PE Ratio (TTM)

-55.77

Industry PE ratio

-14.14

PEG Ratio

0.5576952236542835

EBITDA

-3.2M

Revenue (TTM)

357.3M

Profit Margin

77.26%

Return On Equity TTM

-4.15%

Castle Biosciences Stock Valuation

Track how Castle Biosciences P/E has moved over time to understand its valuation trends.

Castle Biosciences in the last 5 years

  • Overview

  • Trends

Lowest (-46.87x)

December 31, 2025

Today (-46.87x)

December 31, 2025

Industry (-14.14x)

December 31, 2025

Highest (40.57x)

December 31, 2024

LowHigh

Today’s Price to Earnings Ratio: -46.87x

Castle Biosciences vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Castle Biosciences with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %Dividend Yield %
Castle Biosciences image
Castle Biosciences
BUY$1.1B-52.43%-55.7777.26%0.00%
Natera image
Natera
BUY$49.8B189.89%-269.3565.30%0.00%
IQVIA Holdings image
IQVIA Holdings
BUY$44.8B5.11%33.1726.23%0.00%
Thermo Fisher image
Thermo Fisher
BUY$237.2B10.31%35.3640.37%0.28%
Danaher image
Danaher
BUY$147.2B-34.52%37.0458.51%0.69%

Stock Returns calculator for Castle Biosciences Stock including INR - Dollar returns

The Castle Biosciences stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.

Investment Value

₹1,00,000

  • 1Y

  • 3Y

  • 5Y

  • 7Y

Castle Biosciences investment value today

Current value as on today

₹1,57,200

Returns

₹57,200

(+57.2%)

Returns from Castle Biosciences Stock

₹44,777 (+44.78%)

Dollar Impact

₹12,423 (+12.42%)

Analyst Recommendation on Castle Biosciences Stock

Based on 5 analysts

BUY

100.00%

Buy

0.00%

Hold

0.00%

Sell

Based on 5 analysts, 100% of analysts recommend a 'BUY' rating for Castle Biosciences. Average target price of $44

Castle Biosciences Share Price Target

Get share price movements and forecasts by analysts on Castle Biosciences.

What analysts predicted

19.68%UPSIDE

Target Price

$44

Current Price

$35.34

Analyzed by

5 Analysts

Target

$44.00

Castle Biosciences target price $44, a slight upside of 19.68% compared to current price of $35.34. According to 5 analysts rating.

Indian Investors' Interest in Castle Biosciences Stock

Search interest for Castle Biosciences Stock has decreased by -28% in the last 30 days, reflecting a downward trend in search activity.

Time period: to

Change:-28% versus previous 30 day period

Castle Biosciences Quarterly Profit & Loss

All numbers in Millions USD

Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Mar 2026
Jun 2026
Total Revenue
72
87
85
86
87
86
83
87
83
103
Gross Profit
59
72
70
70
71
68
64
68
63
79
Operating Income
-5
5
5
4
-27
-4
-6
-3
-18
-3
EBITDA
0
11
12
13
3
3
3
1
-10
2
Interest Expense
0
0
0
0
0
0
0
0
0
0
Depreciation
3
3
3
5
29
3
3
3
3
4
Income Before Tax
-2
7
8
7
-26
0
0
-2
-14
-1
Income Tax Expense
0
-1
6
-1
0
-4
0
0
0
0
Net Income
-2
8
2
9
-25
4
0
-2
-14
-2
Net Profit Margin
80.96%
83.31%
81.80%
81.25%
81.38%
79.55%
77.48%
78.95%
75.46%
77.11%

Castle Biosciences Annual Profit & Loss

All numbers in Millions USD

Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Total Revenue
13
22
51
62
94
137
219
332
344
Gross Profit
8
17
44
52
78
105
174
271
273
Operating Income
-10
-3
7
-6
-40
-72
-67
8
-42
EBITDA
-10
-3
10
-7
-36
-58
-45
38
11
Interest Expense
1
2
4
2
0
0
0
0
0
Depreciation
0
0
0
0
3
10
12
15
40
Income Before Tax
-12
-6
5
-10
-40
-68
-57
21
-29
Income Tax Expense
0
0
0
0
-8
-1
0
3
-5
Net Income
-12
-6
5
-10
-31
-67
-57
18
-24
Net Profit Margin
64.21%
76.75%
85.91%
84.54%
83.18%
76.64%
79.53%
81.87%
79.37%

Castle Biosciences Quarterly Cash Flow

All numbers in Millions USD

Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Mar 2026
Jun 2026
Net Income
-2
8
2
9
-25
4
0
-2
-14
-2
Operating Cash Flow
-6
23
23
24
-6
20
22
26
-22
15
Investing Cash Flow
-19
-21
-14
5
-22
-28
-18
8
-25
-15
Financing Cash Flow
10
0
0
-5
-1
0
0
-4
-5
0
Change in Cash
-15
2
9
24
-30
-7
3
31
-52
-1

Castle Biosciences Annual Cash Flow

All numbers in Millions USD

Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Net Income
-12
-6
5
-10
-31
-67
-57
18
-24
Operating Cash Flow
-12
-12
7
9
-18
-41
-5
64
64
Investing Cash Flow
0
0
0
-4
-66
-166
-16
-50
-60
Financing Cash Flow
8
15
88
305
5
1
-2
6
-6
Change in Cash
-3
3
94
311
-80
-206
-24
20
-2

Mutual Funds that own Castle Biosciences Stock

Check out the Mutual Funds with significant holdings in Castle Biosciences.

Funds
Holdings
Shares Held
VANGUARD INDEX FUNDS
3.762872%
1149539
Buffalo Funds
2.510878%
767061
Principal Funds, Inc
2.321314%
709150
Fidelity Rutland Square Trust II
1.875369%
572916
DFA INVESTMENT DIMENSIONS GROUP INC
1.601639%
489293
See all

Global Institutional Holdings in Castle Biosciences

Funds
Holdings
iShares
5.77%
Vanguard
4.88%
Dimensional
0.98%
SPDR
0.78%
Schwab
0.54%
See all

Castle Biosciences News & Key Events

  • img

    Today's Timeline - 27 February

    Fri, 09:44 PM

    -

    Castle Biosciences maintains Zacks Rank #1; loss estimates narrowed, shares up 54.6% over six months.

Insights on Castle Biosciences

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Revenue Rich

    img

    Revenue is up for the last 2 quarters, 83.67M → 103.54M (in $), with an average increase of 19.2% per quarter

  • imgPOSITIVE IMPACT

    Profit Spike

    img

    Netprofit is up for the last 2 quarters, -14.52M → -2.06M (in $), with an average increase of 605.0% per quarter

  • imgPOSITIVE IMPACT

    Price Rise

    img

    In the last 7 days, CSTL stock has moved up by 9.3%

  • imgNO EFFECT

    Against Peers

    img

    In the last 1 year, Natera, Inc. Common Stock has given 104.0% return, outperforming this stock by 59.2%

  • imgNO EFFECT

    Against Peers

    img

    In the last 3 years, Natera, Inc. Common Stock has given 651.4% return, outperforming this stock by 542.8%

About Castle Biosciences

Castle Biosciences, Inc. functions as a commercial-stage diagnostics firm, with its primary objective being the provision of both diagnostic and prognostic testing services, specifically targeting various dermatological cancers. Their flagship product, DecisionDx-Melanoma, represents an advanced multi-gene expression profile (GEP) assay engineered to assess the probability of metastasis in patients afflicted with invasive cutaneous melanoma. In addition to their leading solution, the company has created several other specialized, proprietary tests. Among these is DecisionDx-UM, a GEP test tailored to forecast the risk of metastasis for individuals with uveal melanoma, a less common malignancy of the eye. Another key offering is DecisionDx-SCC, a distinctive 40-gene expression profile test that utilizes a patient's unique tumor biology to predict their specific risk of squamous cell carcinoma metastasis, particularly for those presenting with recognized risk factors. Moreover, they offer DecisionDx DiffDx-Melanoma and myPath Melanoma, both proprietary GEP tests employed to assist in the accurate diagnosis of ambiguous pigmented lesions. These specialized testing services are provided by Castle Biosciences to patients predominantly through their healthcare providers. The organization commenced operations in 2007 and maintains its corporate headquarters in Friendswood, Texas.
OrganisationCastle Biosciences
Headquarters1500 W. Parkwood Ave, Friendswood, TX, 77546, US
IndustryMedical - Diagnostics & Research
CEODerek J. Maetzold
E-voting on sharesClick here to vote

Key Management of Castle Biosciences

Name

Title

Ms. Trisha Poteet

Senior VP of Clinical Services & Manufacturing Operations

Dr. Hillary Caruso Ph.D.

Chief of Staff

Mr. Derek J. Maetzold

Founder, CEO, President & Director

Ms. Kristen M. Oelschlager R.N.

Chief Operating Officer

Ms. Keli Greenberg

Vice President of Human Resources

Dr. Matthew Goldberg M.D.

Senior Vice President of Medical

Mr. Frank Stokes

CFO & Treasurer

Mr. Tobin W. Juvenal

Chief Commercial Officer

Ms. Camilla Zuckero

Vice President of Investor Relations & Corporate Affairs

FAQs

What is Castle Biosciences share price today?

Castle Biosciences share price today is $35.34 as on at the close of the market. Castle Biosciences share today touched a day high of $36.54 and a low of $35.38.

What is the 52 week high and 52 week low for Castle Biosciences share?

Castle Biosciences share touched a 52 week high of $44.28 on and a 52 week low of $17.72 on . Castle Biosciences stock price today i.e. is closed at $35.34,which is 20.19% down from its 52 week high and 99.41% up from its 52 week low.

What is Castle Biosciences's market capitalisation today?

Castle Biosciences market capitalisation is $0.00T as on .

How to invest in Castle Biosciences Stock (CSTL) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Castle Biosciences on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Castle Biosciences Shares that will get you 0.0424 shares as per Castle Biosciences share price of $35.34 per share as on September 19, 2026 at 8:46 am IST.

What is the minimum amount required to buy Castle Biosciences Stock (CSTL) from India?

Indian investors can start investing in Castle Biosciences (CSTL) shares with as little as ₹95.88 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹958.80 in Castle Biosciences stock (as per the Rupee-Dollar exchange rate as on ). Based on Castle Biosciences share’s latest price of $35.34 as on September 19, 2026 at 8:46 am IST, you will get 0.2830 shares of Castle Biosciences. Learn more about fractional shares .

What are the returns that Castle Biosciences has given to Indian investors in the last 5 years?

Castle Biosciences stock has given -52.43% share price returns and 30.25% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?