Spyre Therapeutics Stock Performance
as on August 22, 2026 at 6:16 am IST
Day's Low
Day's High
$105.71$109.81
1.05%
Downside
2.79%
Upside
52 Week's Low
52 Week's High
$14.51$108.1486.42%
Downside
1.23%
Upside
Spyre Therapeutics share price movements today
- Previous Close
- $107.79
- Open
- $109.00
- Volume
- 566.5K
- Market Cap
- $9.0B
- Day's Low - High
- $105.71 - $109.81
- 52 Week Low - High
- $14.51 - $108.14
Spyre Therapeutics Historical Returns
- 1 Month Return
- + 3.39 %
- 3 Month Return
- + 38.32 %
- 1 Year Return
- + 511.39 %
- 3 Year Return
- 0 %
- 5 Year Return
- 0 %
Spyre Therapeutics Stock Fundamentals & Key Indicators
Check Spyre Therapeutics market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.
Market Cap
$9.0B
EPS (TTM)
-2.8285
Dividend Yield
0.00%
Quarterly Earnings Growth YOY
-1.00%
PE Ratio (TTM)
0PEG Ratio
0EBITDA
-207.8M
Revenue (TTM)
-
Profit Margin
0.00%
Return On Equity TTM
-22.98%
Spyre Therapeutics vs Peer Comparison
Compare market cap, revenue, PE, and other key metrics of Spyre Therapeutics with its industry peers.
Company | Analyst View | Market Cap | 5 Years Return % | PE Ratio | Profit Margin % | Dividend Yield % |
|---|---|---|---|---|---|---|
| BUY | $9.0B | NA | NA | 0.00% | NA | |
| BUY | $43.7B | 669.3% | NA | 0.00% | NA | |
| BUY | $128.2B | 154.86% | 29.82 | 86.04% | NA | |
| BUY | $25.3B | -84.24% | -7.98 | -12.57% | NA | |
| BUY | $82.7B | 24.1% | 19.24 | 84.86% | 0.44999999999999996% |
Stock Returns calculator for Spyre Therapeutics Stock including INR - Dollar returns
The Spyre Therapeutics stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.
*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.
Investment Value
₹1,00,000
Spyre Therapeutics investment value today
Current value as on today
₹6,90,853
Returns
₹5,90,853
(+590.85%)
Returns from Spyre Therapeutics Stock
₹5,30,265 (+530.27%)
Dollar Impact
₹60,587 (+60.59%)
Analyst Recommendation on Spyre Therapeutics Stock
Based on 14 analysts
92.86%
Buy
7.14%
Hold
0.00%
Sell
Based on 14 analysts, 92.85714285714286% of analysts recommend a 'BUY' rating for Spyre Therapeutics. Average target price of $124.71
Spyre Therapeutics Share Price Target
Get share price movements and forecasts by analysts on Spyre Therapeutics.
What analysts predicted
14.34%UPSIDE
Target Price
$124.71
Current Price
$106.83
Analyzed by
14 Analysts
Target
$124.71
Spyre Therapeutics target price $124.71, a slight upside of 14.34% compared to current price of $106.83. According to 14 analysts rating.
Indian Investors' Interest in Spyre Therapeutics Stock
Search interest for Spyre Therapeutics Stock has increased by 17% in the last 30 days, reflecting an upward trend in search activity.
Time period: to
Change:17% versus previous 30 day period
Spyre Therapeutics Quarterly Profit & Loss
All numbers in Millions USD
Spyre Therapeutics Annual Profit & Loss
All numbers in Millions USD
Spyre Therapeutics Quarterly Cash Flow
All numbers in Millions USD
Spyre Therapeutics Annual Cash Flow
All numbers in Millions USD
Spyre Therapeutics News & Key Events
Today's Timeline - 13 October
Tue, 01:31 AM
-Spyre Therapeutics announces proposed public offering of common stock and pre-funded warrants.
Tue, 06:38 AM
-Spyre Therapeutics prices public offering at $18.50 per share, aiming to raise $275 million.
Insights on Spyre Therapeutics
Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.
POSITIVE IMPACTBest in 3 Years
In the last 3 years, SYRE has outperformed top 5 stocks with highest market-cap in its industry
- POSITIVE IMPACT
Price Rise
In the last 1 year, SYRE stock has moved up by 542.4%
- POSITIVE IMPACT
Best in 1 Year
In the last 1 year, SYRE has outperformed top 5 stocks with highest market-cap in its industry
- POSITIVE IMPACT
Revenue Rich
Revenue is up for the last 5 quarters, 168.0K → 90.49M (in $), with an average increase of 54.8% per quarter
- POSITIVE IMPACT
Profit Spike
Netprofit is up for the last 2 quarters, -69.00M → -36.19M (in $), with an average increase of 90.6% per quarter
About Spyre Therapeutics
| Organisation | Spyre Therapeutics |
| Headquarters | Building 23, Waltham, MA, United States, 02453 |
| Industry | Biotechnology |
| CEO | Dr. Cameron Turtle DPHIL, Ph.D. |
| E-voting on shares | Click here to vote |
Key Management of Spyre Therapeutics
Name | Title |
|---|---|
Mr. Eric McIntyre | Senior Vice President of Finance & Investor Relations |
Mr. James Myers | Senior Vice President of Quality & Compliance |
Mr. Scott L. Burrows | Chief Financial Officer |
Dr. Janet Gunzner-Toste M.B.A., Ph.D. | Senior Vice President of Operations |
Dr. Sheldon Sloan M.B.E., M.D. | Chief Medical Officer |
Mr. Brian Connolly | Chief Technical Officer |
Dr. Justin LaFountaine Ph.D. | Senior Vice President of Corporate Development |
Ms. Melissa Cooper | Senior Vice President of People |
Dr. Cameron Turtle DPHIL, Ph.D. | CEO & Director |
Ms. Heidy Abreu King-Jones J.D., L.L.M. | Chief Legal Officer & Corporate Secretary |
FAQs
What is Spyre Therapeutics share price today?
Spyre Therapeutics share price today is $106.83 as on . Spyre Therapeutics share today touched a day high of $109.81 and a low of $105.71.
What is the 52 week high and 52 week low for Spyre Therapeutics share?
Spyre Therapeutics share touched a 52 week high of $108.14 on and a 52 week low of $14.51 on . Spyre Therapeutics stock price today i.e. is trending at $106.83,which is 1.21% down from its 52 week high and 636.50% up from its 52 week low.
What is Spyre Therapeutics's market capitalisation today?
Spyre Therapeutics market capitalisation is $0.01T as on .
How to invest in Spyre Therapeutics Stock (SYRE) from India?
- Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
- Step 2: Search for Spyre Therapeutics on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Spyre Therapeutics Shares that will get you 0.0140 shares as per Spyre Therapeutics share price of $106.83 per share as on August 22, 2026 at 12:46 am IST.
What is the minimum amount required to buy Spyre Therapeutics Stock (SYRE) from India?
Indian investors can start investing in Spyre Therapeutics (SYRE) shares with as little as ₹95.685 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹956.85 in Spyre Therapeutics stock (as per the Rupee-Dollar exchange rate as on ).
Based on Spyre Therapeutics share’s latest price of $106.83 as on August 22, 2026 at 12:46 am IST, you will get 0.0936 shares of Spyre Therapeutics. Learn more about
fractional shares .