Krystal Biotech share price logo

Krystal Biotech

NASDAQ: KRYS

Mid Cap

$348.75

-2.13

(-0.61%)

Live

as on

Krystal Biotech Stock Performance

as on September 24, 2026 at 1:07 am IST

  • Day's Low

    Day's High

    $346.96
    $352.63
    downward going graph

    0.51%

    Downside

    1.11%

    Upside

    downward going graph
  • 52 Week's Low

    52 Week's High

    $158.08
    $382.54
    downward going graph

    54.67%

    Downside

    9.69%

    Upside

    downward going graph

Krystal Biotech share price movements today

Previous Close
$350.88
Open
$351.95
Volume
7.9K
Market Cap
$9.9B
Day's Low - High
$346.96 - $352.63
52 Week Low - High
$158.08 - $382.54

Krystal Biotech Historical Returns

1 Month Return
+ 1.24 %
3 Month Return
+ 3.14 %
1 Year Return
+ 112.69 %
3 Year Return
+ 204.74 %
5 Year Return
+ 507.48 %

Krystal Biotech Stock Fundamentals & Key Indicators

Check Krystal Biotech market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$9.9B

EPS (TTM)

8.27

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.39%

PE Ratio (TTM)

40.37

Industry PE ratio

-13.42

PEG Ratio

0.6494665451119357

EBITDA

218.4M

Revenue (TTM)

440.5M

Profit Margin

93.34%

Return On Equity TTM

19.34%

Krystal Biotech Stock Valuation

Track how Krystal Biotech P/E has moved over time to understand its valuation trends.

Krystal Biotech in the last 5 years

  • Overview

  • Trends

Lowest (-22.32x)

December 31, 2021

Industry (-13.42x)

December 31, 2025

Today (34.82x)

December 31, 2025

Highest (308.15x)

December 31, 2023

LowHigh

Today’s Price to Earnings Ratio: 34.82x

Krystal Biotech vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Krystal Biotech with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %Dividend Yield %
StrongBuy$9.9B507.48%40.3793.34%0.00%
Neutral$69.0B-59.84%-21.67-12.57%0.00%
StrongBuy$129.4B178.24%29.4986.04%0.00%
Buy$80.8B24.34%19.284.86%0.46%

Stock Returns calculator for Krystal Biotech Stock including INR - Dollar returns

The Krystal Biotech stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Impact: The bonus return you make when the US Dollar rises against the Rupee; calculated on the full amount you walk away with, not just what you invested in.

Investment Value

₹1,00,000

  • 1Y

  • 3Y

  • 5Y

  • 7Y

Krystal Biotech investment value today

Current value as on today

₹2,27,903

Returns

₹1,27,903

(+127.9%)

Returns from Krystal Biotech Stock

₹1,11,402 (+111.4%)

Dollar Impact

₹16,501 (+16.5%)

Analyst Recommendation on Krystal Biotech Stock

Based on 8 analysts

BUY

87.50%

Buy

12.50%

Hold

0.00%

Sell

Based on 8 analysts, 87.5% of analysts recommend a 'BUY' rating for Krystal Biotech. Average target price of $386

Krystal Biotech Share Price Target

Get share price movements and forecasts by analysts on Krystal Biotech.

What analysts predicted

9.65%UPSIDE

Target Price

$386

Current Price

$348.75

Analyzed by

8 Analysts

Target

$386.00

Krystal Biotech target price $386, a slight upside of 9.65% compared to current price of $348.75. According to 8 analysts rating.

Indian Investors' Interest in Krystal Biotech Stock

Search interest for Krystal Biotech Stock has decreased by -49% in the last 30 days, reflecting a downward trend in search activity.

Time period: to

Change:-49% versus previous 30 day period

Krystal Biotech Quarterly Profit & Loss

All numbers in Millions USD

Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Mar 2026
Jun 2026
Total Revenue
45
70
83
91
88
96
97
107
116
119
Gross Profit
42
64
77
86
83
88
92
96
110
112
Operating Income
-6
8
22
41
36
39
41
44
53
58
EBITDA
7
23
36
50
45
48
49
39
63
66
Interest Expense
-
-
-
-
-
-
-
-
-
-
Depreciation
1
2
1
1
1
1
1
1
1
-
Income Before Tax
0
16
29
48
43
46
47
51
61
66
Income Tax Expense
-
0
2
3
7
8
-31
0
5
11
Net Income
0
15
27
45
35
38
79
51
55
54
Net Profit Margin
94.65%
91.45%
92.03%
94.57%
94.30%
92.54%
94.21%
89.81%
94.57%
94.60%

Krystal Biotech Annual Profit & Loss

All numbers in Millions USD

Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Total Revenue
-
1
-
-
-
-
50
290
389
Gross Profit
0
0
0
-1
-
-
47
270
360
Operating Income
-4
-11
-22
-32
-68
-145
-109
65
161
EBITDA
-4
-10
-18
-30
-66
-116
-91
109
196
Interest Expense
3
1
-
-
1
-
-
-
-
Depreciation
0
0
0
1
1
3
5
6
6
Income Before Tax
-7
-10
-19
-32
-69
-139
12
95
189
Income Tax Expense
-
0
-
-
-
-
1
6
-15
Net Income
-7
-10
-19
-32
-69
-139
10
89
204
Net Profit Margin
0.00%
86.27%
0.00%
0.00%
0.00%
0.00%
93.90%
93.09%
92.61%

Krystal Biotech Quarterly Cash Flow

All numbers in Millions USD

Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Dec 2025
Mar 2026
Jun 2026
Net Income
0
15
27
45
35
38
79
51
55
54
Operating Cash Flow
15
-4
58
52
30
52
39
77
80
74
Investing Cash Flow
-25
-19
-34
-83
-54
-10
-4
11
-63
-161
Financing Cash Flow
10
10
3
2
-12
1
3
15
-10
15
Change in Cash
0
-13
28
-29
-36
45
38
103
5
-73

Krystal Biotech Annual Cash Flow

All numbers in Millions USD

Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Dec 2025
Net Income
-7
-10
-19
-32
-69
-139
10
89
204
Operating Cash Flow
-3
-9
-18
-26
-47
-100
-88
123
200
Investing Cash Flow
0
-10
-4
-11
-226
-114
82
-163
-58
Financing Cash Flow
51
73
107
118
347
35
202
27
8
Change in Cash
47
54
83
80
72
-179
196
-13
151

Mutual Funds that own Krystal Biotech Stock

Check out the Mutual Funds with significant holdings in Krystal Biotech.

Funds
Holdings
Shares Held
VANGUARD INDEX FUNDS
6.97525%
2064593
Fidelity Select Portfolios
6.103354%
1806522
Fidelity Mt. Vernon Street Trust
4.069541%
1204537
SMALLCAP World Fund Inc
2.541464%
752244
Manager Directed Portfolios
1.114165%
329780

Global Institutional Holdings in Krystal Biotech

Funds
Holdings
Vanguard
8.6%
iShares
7.98%
VANGUARD INDEX FUNDS
6.98%
Fidelity Select Portfolios
6.1%
Fidelity Mt. Vernon Street Trust
4.07%

Insights on Krystal Biotech

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Best in 3 Years

    img

    In the last 3 years, KRYS has outperformed top 5 stocks with highest market-cap in its industry

  • imgPOSITIVE IMPACT

    Price Rise

    img

    In the last 1 year, KRYS stock has moved up by 112.7%

  • imgNO EFFECT

    Against Peers

    img

    In the last 1 year, Moderna, Inc. Common Stock has given 607.9% return, outperforming this stock by 495.2%

About Krystal Biotech

Krystal Biotech, Inc. is a clinical-stage biotechnology company focused on developing redosable gene therapies to address severe orphan diseases across the United States. Its most advanced therapeutic candidate, beremagene geperpavec (B-VEC), is currently undergoing Phase III clinical evaluation for the treatment of dystrophic epidermolysis bullosa. The company's pipeline also includes several other promising programs: KB105 is in Phase I/II clinical trials for patients suffering from deficient autosomal recessive congenital ichthyosis; KB301 is also in Phase I/II development, aiming to ameliorate wrinkles and other signs of aging or damaged skin. Additionally, Krystal Biotech is conducting preclinical research on KB407 for cystic fibrosis and KB104 for Netherton syndrome. In its earlier discovery phase, the company is exploring candidates such as KB5xx for chronic skin conditions and multiple KB3xx programs targeting aesthetic dermatological concerns. Krystal Biotech, Inc. was established in 2015 and is based in Pittsburgh, Pennsylvania.
OrganisationKrystal Biotech
Headquarters2100 Wharton Street, Pittsburgh, PA, 15203, US
IndustryBiotechnology
CEOKrish S. Krishnan
E-voting on sharesClick here to vote

Key Management of Krystal Biotech

Name

Title

Ms. Kathryn A. Romano CPA

Executive VP & Chief Accounting Officer

Mr. John C. Thomas

EVP, General Counsel & Corporate Secretary

Mr. John Karakkal

Vice President of North American Sales & Marketing

Dr. Stephane Paquette Ph.D.

Senior Vice President of Corporate Development

Mr. Laurent Goux

Executive VP & Head of International

Mr. Krish S. Krishnan M.B.A., M.S.

Founder, Chairman, President & CEO

Ms. Suma M. Krishnan

Founder, President of R&D and Director

Mr. Josh Suskin

Senior Director & Head of US Human Resources

Dr. David Chien M.D.

Senior Vice President of Clinical Development

Ms. Christine Wilson

Senior VP & Head of US Commercial

FAQs

What is Krystal Biotech share price today?

Krystal Biotech share price today is $348.75 as on . Krystal Biotech share today touched a day high of $352.63 and a low of $346.96.

What is the 52 week high and 52 week low for Krystal Biotech share?

Krystal Biotech share touched a 52 week high of $382.54 on and a 52 week low of $158.08 on . Krystal Biotech stock price today i.e. is trending at $348.75,which is 8.83% down from its 52 week high and 120.62% up from its 52 week low.

What is Krystal Biotech's market capitalisation today?

Krystal Biotech market capitalisation is $0.01T as on .

How to invest in Krystal Biotech Stock (KRYS) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Krystal Biotech on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Krystal Biotech Shares that will get you 0.0043 shares as per Krystal Biotech share price of $348.75 per share as on September 23, 2026 at 7:37 pm IST.

What is the minimum amount required to buy Krystal Biotech Stock (KRYS) from India?

Indian investors can start investing in Krystal Biotech (KRYS) shares with as little as ₹95.74 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹957.40 in Krystal Biotech stock (as per the Rupee-Dollar exchange rate as on ). Based on Krystal Biotech share’s latest price of $348.75 as on September 23, 2026 at 7:37 pm IST, you will get 0.0287 shares of Krystal Biotech. Learn more about fractional shares .

What are the returns that Krystal Biotech has given to Indian investors in the last 5 years?

Krystal Biotech stock has given 507.48% share price returns and 29.82% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?