Apellis Pharmaceuticals Inc share price logo

Apellis Pharmaceuticals Inc Share Price

NASDAQ: APLS

Mid Cap

$20.83

-0.64

(-2.98%)

Live

as on

Apellis Pharmaceuticals Inc Stock Performance

as on November 3, 2025 at 10:41 pm IST

  • Day's Low

    Day's High

    $20.57
    $21.41
    downward going graph

    1.25%

    Downside

    2.78%

    Upside

    downward going graph
  • 52 Week's Low

    52 Week's High

    $16.1
    $35.72
    downward going graph

    22.71%

    Downside

    71.48%

    Upside

    downward going graph

Apellis Pharmaceuticals Inc share price movements today

Previous Close
$21.47
Open
$21.25
Volume
869.3K
Day's Low - High
$20.57 - $21.41
52 Week Low - High
$16.1 - $35.72

Apellis Pharmaceuticals Inc Historical Returns

1 Month Return
-9.79 %
3 Month Return
-6.45 %
1 Year Return
-23.27 %
3 Year Return
-64.25 %
5 Year Return
-35.85 %

Apellis Pharmaceuticals Inc Stock Fundamentals & Key Indicators

Check Apellis Pharmaceuticals Inc market cap, PE, PB, PEG ratios, dividend yield, and other key fundamental indicators.

Market Cap

$2.7B

EPS (TTM)

-0.173

Dividend Yield

0.00%

Quarterly Earnings Growth YOY

0.00%

PE Ratio (TTM)

59.64

Industry PE ratio

8.355964912280701

PEG Ratio

0

EBITDA

82.1M

Revenue (TTM)

1.0B

Profit Margin

4.43%

Return On Equity TTM

14.10%

Apellis Pharmaceuticals Inc Stock Valuation

Track how Apellis Pharmaceuticals Inc P/E has moved over time to understand its valuation trends.

Apellis Pharmaceuticals Inc in the last 5 years

  • Overview

  • Trends

Lowest (-20.71x)

December 31, 2024

Industry (8.36x)

November 3, 2025

Today (59.64x)

November 3, 2025

Highest (-4.41x)

December 31, 2021

LowHigh

Today’s Price to Earnings Ratio: 59.64x

Apellis Pharmaceuticals Inc vs Peer Comparison

Compare market cap, revenue, PE, and other key metrics of Apellis Pharmaceuticals Inc with its industry peers.

Company
Analyst View
Market Cap
5 Years Return %PE RatioProfit Margin %
BUY$2.7B-35.85%59.644.43%
BUY$40.4B478.23%-16.34-264.83%
BUY$60.2B253.38%1425.121.36%
BUY$109.1B101.56%30.3131.86%
BUY$68.5B16.98%15.6232.13%

Stock Returns calculator for Apellis Pharmaceuticals Inc Stock including INR - Dollar returns

The Apellis Pharmaceuticals Inc stock calculator helps Indian investors calculate returns based on the historical performance of the stock. Just choose your investment amount and duration to get insights and invest more confidently. See stock returns as well as the effect of dollar appreciation over different durations.

*Dollar Return is the profit earned when the US dollar rises in value compared to the Indian rupee.

Investment Value

₹1,00,000

  • 1Y

  • 3Y

  • 5Y

  • 7Y

Apellis Pharmaceuticals Inc investment value today

Current value as on today

₹80,147

Returns

₹19,853

(-19.85%)

Returns from Apellis Pharmaceuticals Inc Stock

₹25,554 (-25.55%)

Dollar Returns*

₹5,701 (+5.7%)

Analyst Recommendation on Apellis Pharmaceuticals Inc Stock

Based on 23 analysts

BUY

82.61%

Buy

17.39%

Hold

0.00%

Sell

Based on 23 analysts, 82.61% of analysts recommend a 'BUY' rating for Apellis Pharmaceuticals Inc. Average target price of $36.22

Apellis Pharmaceuticals Inc Share Price Target

Get share price movements and forecasts by analysts on Apellis Pharmaceuticals Inc.

What analysts predicted

42.49%UPSIDE

Target Price

$36.22

Current Price

$20.83

Analyzed by

23 Analysts

Target

$36.22

Apellis Pharmaceuticals Inc target price $36.22, a slight upside of 42.49% compared to current price of $20.83. According to 23 analysts rating.

Apellis Pharmaceuticals Inc Stock’s Investor Sentiment and Interest

Investment in Apellis Pharmaceuticals Inc Shares on INDmoney has grown by 306.25% over the past 30 days, indicating increased transactional activity.

Time period: to

Change:306.25% versus previous 30 day period

Search interest for Apellis Pharmaceuticals Inc Stock has increased by 100% in the last 30 days, reflecting an upward trend in search activity.

Time period: to

Change:100% versus previous 30 day period

Apellis Pharmaceuticals Inc Quarterly Profit & Loss

All numbers in Millions USD

Jun 2023
Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Total Revenue
94
110
146
172
199
196
212
166
178
177
Gross Profit
-9
87
126
151
176
163
171
132
164
153
Operating Income
-120
-148
-84
-62
-29
-47
-26
-83
-33
223
EBITDA
-114
-132
-79
-58
-27
-43
-24
-80
-30
223
Interest Expense
7
7
7
6
9
12
11
11
11
11
Depreciation
0
0
0
0
0
0
0
0
0
-
Income Before Tax
-121
-140
-87
-66
-37
-56
-36
-91
-41
216
Income Tax Expense
0
0
1
0
0
0
0
0
0
0
Net Income
-122
-140
-88
-66
-37
-57
-36
-92
-42
215
Net Profit Margin
-128.50%
-127.03%
-60.51%
-38.55%
-18.86%
-29.19%
-17.11%
-55.29%
-23.61%
121.36%

Apellis Pharmaceuticals Inc Annual Profit & Loss

All numbers in Millions USD

Dec 2015
Dec 2016
Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Total Revenue
-
-
-
-
-
250
66
75
396
781
Gross Profit
-
-
-50
-127
-288
225
61
69
338
663
Operating Income
-46
-27
-50
-127
-288
-213
-536
-594
-517
-164
EBITDA
6
-27
-50
-125
-298
-312
-731
-617
-495
-154
Interest Expense
-
-
0
2
5
29
13
32
29
40
Depreciation
-
-
0
-
0
0
1
1
1
1
Income Before Tax
-46
-27
-51
-127
-304
-343
-746
-651
-526
-196
Income Tax Expense
-26
-27
0
0
5
1
0
0
2
1
Net Income
-46
-27
-51
-127
-309
-344
-746
-652
-528
-197
Net Profit Margin
0.00%
0.00%
0.00%
0.00%
0.00%
-137.59%
-1121.27%
-864.70%
-133.29%
-25.32%

Apellis Pharmaceuticals Inc Quarterly Cash Flow

All numbers in Millions USD

Sep 2023
Dec 2023
Mar 2024
Jun 2024
Sep 2024
Dec 2024
Mar 2025
Jun 2025
Sep 2025
Net Income
-140
-88
-66
-37
-57
-36
-92
-42
215
Operating Cash Flow
-169
-97
-132
-8
34
19
-53
4
108
Investing Cash Flow
0
0
0
0
-
0
0
0
0
Financing Cash Flow
5
-3
108
42
2
-4
0
6
0
Change in Cash
-163
-101
-25
34
36
14
-52
11
109

Apellis Pharmaceuticals Inc Annual Cash Flow

All numbers in Millions USD

Dec 2016
Dec 2017
Dec 2018
Dec 2019
Dec 2020
Dec 2021
Dec 2022
Dec 2023
Dec 2024
Net Income
-27
-51
-127
-304
-344
-746
-652
-528
-197
Operating Cash Flow
-26
-46
-131
-211
-160
-563
-513
-594
-87
Investing Cash Flow
-1
-1
-1
-1
-316
247
59
0
0
Financing Cash Flow
14
197
131
388
692
392
365
394
149
Change in Cash
-11
150
0
175
215
74
-88
-200
60

Global Institutional Holdings in Apellis Pharmaceuticals Inc

Funds
Holdings
venBio Select Advisor LLC
9.68%
EcoR1 Capital, LLC
9.42%
Vanguard Group Inc
8.04%
Morgan Stanley - Brokerage Accounts
7.72%
Wellington Management Company LLP
7.11%

Insights on Apellis Pharmaceuticals Inc

Insights help you understand the recent movement of the company's critical parameters, giving you an overall view of the company.

  • imgPOSITIVE IMPACT

    Profit Spike

    img

    Netprofit is up for the last 3 quarters, -92.22M → 215.71M (in $), with an average increase of 119.2% per quarter

  • imgNO EFFECT

    Against Peers

    img

    In the last 3 years, Insmed Incorporated has given 958.0% return, outperforming this stock by 1022.2%

  • imgNO EFFECT

    Against Peers

    img

    In the last 1 year, Insmed Incorporated has given 177.5% return, outperforming this stock by 200.8%

  • imgNEGATIVE IMPACT

    Price Dip

    img

    In the last 7 days, APLS stock has moved down by -27.9%

  • imgNEGATIVE IMPACT

    Revenue Fall

    img

    Revenue is down for the last 2 quarters, 178.49M → 177.75M (in $), with an average decrease of 0.4% per quarter

About Apellis Pharmaceuticals Inc

apellis pharmaceuticals is an early stage biotechnology company applying immunotherapy to auto-immune diseases, with an initial emphasis on diseases of the lungs such as asthma and chronic obstructive pulmonary disease (copd), diseases of the retina such as age-related macular degeneration (amd), and rare hematological diseases such as paroxysmal nocturnal hemoglobinuria (pnh). apellis believes that targeting a key element in the immune system called the complement system can have profound disease modifying benefits. we call this approach complement immunotherapy.
OrganisationApellis Pharmaceuticals Inc
Headquarters100 Fifth Avenue, Waltham, MA, United States, 02451
IndustryDistribution Services
CEODr. Cedric Francois M.D., Ph.D.
E-voting on sharesClick here to vote

Key Management of Apellis Pharmaceuticals Inc

Name

Title

Dr. Cedric Francois M.D., Ph.D.

Co-Founder, President, CEO & Director

Mr. Alec Machiels J.D., MBA

Co-Founder & Director

Mr. David O. Watson Esq., J.D.

General Counsel & Secretary

Dr. Caroline R. Baumal M.D.

Chief Medical Officer

Dr. Pascal Deschatelets Ph.D.

Co-Founder & Chief Scientific Officer

Mr. James G. Chopas CPA

VP, Corporate Controller & Chief Accounting Officer

Mr. Timothy E. Sullivan

CFO & Treasurer

Ms. Meredith Kaya

Senior Vice President, Investor Relations & Strategic Finance

Ms. Kelley Boucher

Chief People Officer

Prof. Peter Hillmen M.D., Ph.D.

Head of Hematology Engagement & Member of PNH Scientific Advisory Board

FAQs

What is Apellis Pharmaceuticals Inc share price today?

Apellis Pharmaceuticals Inc share price today is $20.83 as on . Apellis Pharmaceuticals Inc share today touched a day high of $21.41 and a low of $20.57.

What is the 52 week high and 52 week low for Apellis Pharmaceuticals Inc share?

Apellis Pharmaceuticals Inc share touched a 52 week high of $35.72 on and a 52 week low of $16.1 on . Apellis Pharmaceuticals Inc stock price today i.e. is trending at $20.83,which is 41.69% down from its 52 week high and 29.38% up from its 52 week low.

What is Apellis Pharmaceuticals Inc's market capitalisation today?

Apellis Pharmaceuticals Inc market capitalisation is $0.00T as on .

How to invest in Apellis Pharmaceuticals Inc Stock (APLS) from India?

  1. Step 1: Open a free US stocks account on INDmoney App and transfer your Rupees into Dollars to your INDmoney US stocks account. For a step by step instruction, check How to Transfer Money to Your US Stocks Account .
  2. Step 2: Search for Apellis Pharmaceuticals Inc on INDmoney app. Click on Buy button. You can invest as low as $1.5 in Apellis Pharmaceuticals Inc Shares that will get you 0.0720 shares as per Apellis Pharmaceuticals Inc share price of $20.83 per share as on November 3, 2025 at 10:41 pm IST.

What is the minimum amount required to buy Apellis Pharmaceuticals Inc Stock (APLS) from India?

Indian investors can start investing in Apellis Pharmaceuticals Inc (APLS) shares with as little as ₹88.715 or $1 (as of ) using the INDmoney app.
For example: If you want to invest $10 or ₹887.15 in Apellis Pharmaceuticals Inc stock (as per the Rupee-Dollar exchange rate as on ). Based on Apellis Pharmaceuticals Inc share’s latest price of $20.83 as on November 3, 2025 at 10:41 pm IST, you will get 0.4801 shares of Apellis Pharmaceuticals Inc. Learn more about fractional shares .

What are the returns that Apellis Pharmaceuticals Inc has given to Indian investors in the last 5 years?

Apellis Pharmaceuticals Inc stock has given -35.85% share price returns and 21.02% dollar appreciation to an Indian investor in the last 5 years.
Read more about How do Currency Exchange Rates impact your returns on US Stock Investments?